PROGESTERONE ANTAGONISTS SUCH AS CDB-4124 IN THE TREATMENT OF ENDOMETRIOSIS, UTERINE FIBROIDS, DYSMENORRHEA, BREAST CANCER, ETC.

2011
OA: closed
⚙ AI-generated summary by qwen3.7-flash, 2026-09-08 ⓘ

This invention discloses methods for treating estrogen-dependent conditions, including endometriosis and uterine fibroids, using progesterone receptor antagonists like CDB-4124 to suppress endometrial proliferation and alleviate associated pain.

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Abstract

The present invention relates to methods of administering compositions comprising a progesterone receptor antagonist for use in treating estrogen-dependent conditions. The invention is also directed to methods for treating pain associated with endometriosis. The compositions may be administered to females with endometriosis as well as to females undergoing estrogen and/or selective estrogen receptor modulator (SERM) therapy. In certain embodiments, the invention provides a method for suppressing endometrial proliferation.

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europepmc
last seen: 2026-10-09T06:09:53.026058+00:00