Pharmaceutical care needs of patients with chronic respiratory diseases：results from a cross sectional study

Pharmaceutical care needs of patients with chronic respiratory diseases：results from a cross sectional study | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article Pharmaceutical care needs of patients with chronic respiratory diseases：results from a cross sectional study Jin Zhang, Shuiqing Zhang, Qi Lin, Yingying Li, Maobai Liu, Muying Yang This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-6702396/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract Background Chronic airway diseases (CADs) impose substantial health burdens due to poor medication adherence, inhaler misuse, and insufficient disease knowledge, which compromise disease control. Understanding patients' pharmaceutical care needs is critical to improving chronic respiratory disease management. Method A cross-sectional survey was conducted among 131 CADs patients attending a pharmaceutical outpatient clinic at a tertiary hospital in Fujian Province, China, from June to August 2024. Data were collected on patients' care priorities, communication preferences, service satisfaction, and influencing factors. Results Patients prioritized medication guidance (74.81%), disease knowledge (65.65%), and self-management skills (58.02%). Face-to-face communication (77.86%) and concise information delivery (54.96%) were preferred. Despite high satisfaction (90.08%), 54.20% held misconceptions about medication safety (e.g., accepting occasional dose skipping). Physician referrals drove service utilization (90.08%), with minimal influence from external channels like social media. Conclusion Pharmaceutical services for CADs patients should integrate technical support (e.g., inhaler training), patient education, family engagement, and multidisciplinary collaboration. Optimizing service models, enhancing public awareness, and securing policy support are essential to advancing precision pharmaceutical care. Chronic airway diseases COPD asthma pharmaceutical services medication adherence Figures Figure 1 Figure 2 Introduction Chronic airway diseases (CADs) are a group of chronic diseases characterised by airway inflammation and airflow limitation, mainly including chronic obstructive pulmonary disease (COPD) and bronchial asthma. According to the Global Burden of Disease Study, COPD has become the third leading cause of death in the world [1], and the prevalence of COPD in people over 40 years of age in China is as high as 13.7% [2], representing a large patient base and a heavy disease burden. The disease is characterised by a long disease course, recurrent acute exacerbations and the need for long-term medication, and patients must continue to use inhalers and oral medications to control symptoms and slow the decline in lung function. However, studies have shown that patients with chronic respiratory diseases generally have low medication adherence (approximately 30-50%) [3], an 80% error rate in the use of inhalers [4], and a serious lack of disease knowledge and self-management skills, leading to poor disease control, frequent acute exacerbations and increased healthcare costs. In recent years, with the deepening of the concept of 'patient-centred' medical services, pharmacy services have gradually shifted from traditional drug supply to more sophisticated and individualised medication management. Studies have shown that pharmacist-led pharmacy interventions, such as inhaler technique instruction, medication adherence education, and adverse drug reaction monitoring, can significantly improve patients' clinical outcomes [5, 6] . However, the existing pharmacy service model focuses mainly on the treatment phase of the disease and pays insufficient attention to long-term follow-up, health empowerment and the diverse needs of patients, such as psychological support and alleviation of economic burden [7] . In addition, the pharmacy service needs of patients with chronic respiratory diseases in China have not been systematically studied, and there is a mismatch between the service content and the actual needs of patients, which limits the accurate implementation of pharmacy services. Therefore, this study aims to systematically analyse the current situation and factors influencing the demand for pharmacy services among patients with chronic respiratory diseases through a cross-sectional survey, and to explore patients' core needs for medication counseling and disease management services to provide an evidence-based basis for optimising the pharmacy service model and improving patients' health outcomes. The results of this study will also help promote the prevention and treatment of chronic respiratory diseases in the framework of the "Healthy China 2030" plan, and provide a reference for the rational allocation of resources in the charging policy for pharmacy services. Methods Study design and participants This hospital-based cross-sectional study was conducted at the Affiliated Union Hospital of Fujian Medical University in Fujian Province, China, from June to August 2024. We used a self-developed questionnaire to assess the pharmaceutical care needs of patients with chronic respiratory diseases, including chronic obstructive pulmonary disease, asthma, and COPD-asthma overlap syndrome. The study protocol received ethical approval from the institutional review board. Survey instrument and implementation The "Questionnaire on Pharmaceutical Care Services for Patients with Chronic Airway Diseases" consists of three sections. Section one includes 7 questions on patients' basic information, such as age, sex, disease type, smoking status, education level, and income. Section two concerns patients' needs and preferences for pharmaceutical care services. This part is further divided into four subsections, consisting of 25 questions, such as 4 questions assessing patients' knowledge of their disease, 10 questions on content preferences, 4 on expression preferences and 7 questions about the influence of publicity, particularly how patients learned about the outpatient pharmacy. Section three includes 11 questions evaluating the pharmacy services provided by the outpatient pharmacy. The second section ( Disease and Medication Cognition and Content Preferences) and the third section use a five - point Likert - type scale (1 = strongly disagree / not interested at all, 2 = disagree / not very interested, 3 = neutral, 4 = agree / interested, 5 = strongly agree / very interested) for data collection. Detailed information can be found in the supplementary file. In this study, data were collected via paper questionnaires completed by chronic airway disease patients at our pharmacy clinic. After unified training, outpatient pharmacists distributed the questionnaires, explained their purpose to eligible patients, instructed participants to complete them upon understanding, and collected the questionnaires on-site. Statistical analysis The returned questionnaires were uniformly numbered. Two individuals entered the data. We collated all the collected data using Microsoft Excel 2019 and, after checking for errors, imported the data into SPSS 26.0 software for statistical analysis. We described the characteristics of participants, patients' pharmaceutical care service preferences, and the influence of publicity using frequencies and percentages. As for patients' knowledge of their disease and medication use, we used a bar chart for illustration. Count data were expressed as the number of cases (%). Results Characteristics of the participants In this study, 157 patients with chronic airway disease visited the pharmacy clinic between June and August 2024, of whom 131 completed the questionnaire, yielding an 83.43% response rate. The patients' ages ranged from 18 to 85 years, and the majority were male, accounting for 65.65% of the participants. The educational level of the participants was predominantly low, with 70.99% having junior high school education or below. In terms of disease distribution, COPD was the most common condition, affecting 46.56% of the patients, followed by asthma at 44.27%. Further demographic details are outlined in Table 1. Patients' knowledge of disease and medication Patients exhibited notable differences in their understanding of disease management and medication. A substantial 97.71% agreed, to some extent, that "the right medication can control symptoms well," with over half (51.91%) strongly endorsing this view. However, a significant portion (54.20%) also acknowledged that "it is OK not to take medication sometimes". Furthermore, concerns over long-term medication were prevalent, with 56.48% of patients worried about potential harm to the body and drug dependence. These findings are elaborated in Fig.1. Preferences for pharmacy services Patients' preferences for pharmacy services centred on disease knowledge, medication advice, and self-management skills. Specifically, 89.31% were highly interested in medication usage and dosage, 75.57% in the duration of medication regimen, and 70.99% in acute attack management. Additionally, over 60% of patients showed strong interest in dietary contraindications and exercise advice, indicating a significant demand for self-management knowledge. These details are illustrated in Table 2. Patients had distinct preferences regarding communication styles and adherence strategies. The majority (77.86%) favored "face-to-face communication" for disease and medication information, while 54.96% preferred pharmacists to "focus on key points" rather than detailed explanations. When it came to improving medication adherence, 44.27% found the "combination of encouragement and reminders" most effective. Interestingly, 56.49% did not object to "stern warnings," indicating a tolerance for direct advice. These preferences highlight the need for personalized communication approaches in pharmacy services. (Table 3) Influence of advertising Patients' acceptance of pharmacy services was predominantly driven by recommendations from their attending physicians (90.08%), which was significantly more influential than social media recommendations (52.67%) or peer recommendations from other patients (16.03%). These latter two channels had substantially lower influence. (Figure 2) Evaluation of pharmacy services The pharmacy service received high satisfaction from patients, with 90.08% expressing satisfaction. A significant majority (81.68%) acknowledged its importance for disease management, and 83.97% indicated a willingness to continue seeking help from pharmacists. However, a small percentage of patients (3.05% to 6.11%) had reservations about the service's effectiveness. The data also showed strong patient agreement with the pharmacist's role in treatment advice and guidance (79.39%), and most patients (73.28%) felt they could apply the knowledge provided for self-management. Additionally, 80.15% believed the service improved medication adherence and treatment outcomes. (Table 4) Discussion This study revealed that while most patients acknowledge the importance of correct medication use, concerns about the safety of long-term medication use and dependence are significant. For instance, 54.20% of patients agreed to varying degrees that 'it's okay if I occasionally don’t take medication for my illness', which aligns with the low adherence reported by Vestbo et al. [3]. The issue of medication adherence in patients with chronic respiratory diseases is a complex and pervasive challenge. Studies have shown that pharmacy services can play an important role in improving patients' medication adherence [8-11] . Through pharmacy services, pharmacists can provide patients with personalised medication advice and education, which can improve patients' knowledge and understanding of medications and thus improve medication adherence [12] . In patients with chronic obstructive pulmonary disease (COPD), pharmacy service interventions have been shown to significantly improve patients' medication adherence and health-related knowledge [13-15] . Pharmacist education and management increased patients' knowledge of their disease and confidence in their medication, which contributed to reduced hospitalisation rates and improved overall health [12, 16, 17] . In addition, pharmacy services can help physicians understand patients' medication use by providing a feedback mechanism to adjust treatment regimens to improve patient adherence. Studies have shown that providing feedback to physicians on patient medication use can facilitate physician-patient communication and improve the medication management process, and although the direct impact of this feedback mechanism on medication adherence and patient health outcomes may be limited, it is potentially valuable in improving healthcare delivery processes [18] . In conclusion, improving patient knowledge and adherence to medication through pharmacy services not only improves health outcomes for patients with chronic respiratory disease, but also effectively reduces healthcare resource use and associated healthcare costs [19] . A significant proportion of patients, over 50%, express a desire for pharmacists to offer post-pharmacy health education materials. These materials, which include popular science articles, videos, and disease science brochures, can help patients enhance their health literacy, correct misconceptions, and expand their knowledge of diseases [5] . Studies have shown that the readability and understandability of patient education materials are crucial for improving patient adherence [20, 21] . Simplifying these materials is a key strategy to boost patient knowledge and adherence. For instance, a study assessing asthma patient education materials found that many were written above the recommended sixth-grade reading level, potentially hindering patients' understanding and adherence to treatment recommendations [22] . Moreover, combining audiovisual media, such as scientific videos, has proven effective in enhancing patient awareness [23-25] . Video, as an educational tool, offers the benefits of low cost and rapid dissemination, making it highly applicable for chronic disease management and learning [26] . In a randomised clinical trial, researchers compared the effects of infographics and videos on medication adherence in asthma patients and showed that both formats improved adherence, but infographics may have a longer-term advantage as they don't require devices [27] . Pharmacy service needs of patients follow a hierarchical structure. Basic needs, such as medication administration guidance, are prioritised over higher-order needs, such as drug interaction information. This is consistent with the findings of Melani et al. [4], who highlighted the "high error rate in the use of inhaler devices" among patients. Their research underscores the necessity for pharmacists to first address technical difficulties before progressively incorporating comprehensive disease management strategies. In practical terms, this stratified approach ensures that patients receive the most essential support first. By prioritising basic needs, pharmacists can correct fundamental misunderstandings and ensure proper medication use, which is vital for treatment efficacy and patient safety. Pharmacists can significantly improve treatment outcomes by spending time demonstrating correct inhaler techniques and allowing patients to practice under their supervision. Furthermore, patients' significant concerns about 'exercise advice' (60.13%) and 'diet management' (61.83%) highlight the multifaceted nature of chronic disease management [7] .The notable percentage of patients concerned about these aspects reflects growing patient recognition of health's holistic nature. Chronic disease management involves not only medication but also lifestyle adjustments to complement medical treatments. Pharmacists can collaborate with other healthcare professionals, such as dietitians and physical therapists, to develop comprehensive care plans integrating these various aspects. This multidisciplinary approach not only enhances patient satisfaction but also leads to better long-term health outcomes by addressing the full spectrum of patient needs. Patients exhibit distinct preferences regarding communication methods with pharmaceutical service providers. Our data reveal that patients favor face - to - face communication (77.86%) and targeted messaging (54.96%). This aligns with Baggott et al.'s [7] "personalized communication" concept in pharmaceutical services, which stresses adapting communication strategies to individual patients. Notably, 19.85% of patients still get information indirectly through family members, which might be due to low patient literacy or language barriers. This indicates that in pharmaceutical services, the actual situations of patients and their family members should be considered, and the "family - participatory education" concept should be explored, particularly for elderly patients or those with low education. Moreover, remote consulting via WeChat and other platforms can supplement face - to - face communication, further enhancing the accessibility and convenience of pharmaceutical services [6] . In China, pharmacy clinics are a new concept for patients, requiring a process of acceptance. Currently, patients' acceptance of pharmacy services is mainly driven by the recommendation of attending physicians, with a recommendation rate of up to 90.08%. This shows that attending physicians' opinions are crucial in patients' decision-making regarding pharmacy services. In contrast, social media's influence, at 52.67%, is relatively limited, indicating that pharmacy service promotion still heavily depends on in-hospital channels. However, with technological advancements and shifting information dissemination patterns, it is necessary to explore more effective promotion models. Future strategies could include multi-dimensional approaches. For example, joint patient education activities with community health organizations can utilize their resources and influence to reach more patients. Additionally, spreading popular science content via short - video platforms, which have a large user base and strong dissemination power, can help popularize pharmacy knowledge and services among the general public. These methods can increase the visibility of pharmacy services, improve patients' understanding and acceptance, and ultimately promote the development and application of pharmacy clinics. While patient satisfaction with current pharmacy services is high (90.08%), a notable minority (3.05% - 6.11%) express doubts regarding service effectiveness. These findings suggest that despite overall positive perceptions, there remains room for improvement and innovation pharmacy in care delivery. To address these concerns, future directions could involve exploring diversified service models supported by health insurance policies. Such models could include long-term follow-up programs to monitor patient progress and medication adherence. Additionally, health empowerment initiatives could provide patients with more knowledge and tools for self-management. Establishing a collaborative pharmacist-patient management mechanism is another valuable opportunity. This approach would facilitate active engagement between healthcare providers and patients, potentially leading to better health outcomes through personalized care plans and ongoing communication. Conclusion This cross - sectional study analysed the pharmaceutical care needs of 131 patients with chronic airway diseases (CADs) at a tertiary hospital in Fujian Province from June to August 2024. Results showed patients' core needs were medication guidance (89.31%), disease knowledge (including medication duration (75.57%) and management of acute exacerbations (70.99%)) , and self - management skills (over 60%). Most patients (77.86%) preferred face - to - face communication, and 54.96% wanted pharmacists to highlight key information. Despite 90.08% satisfaction with pharmaceutical services, many patients (56.48%) had varying degrees of concern about the long-term safety of medication. Most patients (90.08%) were driven to seek services by their physicians' recommendations, while social media had limited influence. Pharmaceutical services should prioritise technical issues like inhaler use and integrate educational materials, family involvement, and multidisciplinary resources to meet diverse needs. Future efforts should focus on optimising service models, enhancing promotion, and securing policy support to improve the precision of pharmaceutical care and support chronic respiratory disease management goals. Abbreviations CADs Chronic Airway Diseases COPD Chronic Obstructive Pulmonary Disease. Declarations Acknowledgements Not applicable. Conflicts of interest There are no conficts of interest declared. Authors’ contributions Questionnaire Design: Jin Zhang, Qi Lin, Maobai Liu, Muying Yang; Methodology: Jin Zhang, Muying Yang; Questionnaire Administration: Jin Zhang, Shuiqing Zhang, Yingying Li; Data Organization and Analysis: Jin Zhang, Shuiqing Zhang, Qi Lin; Writing - original draft preparation: Jin Zhang; Writing - review and editing: Jin Zhang, Qi Lin, Maobai Liu, Muying Yang. All authors read and approved the final manuscript. Funding Provincial key Clinical Department of Fujian Province (0802713) Availability of data and materials The datasets used and analysed during the current study are available from the corresponding author on reasonable request. Ethics approval and consent to participate First, we followed the Declaration of Helsinki Ethics Principles for Medical Research Involving Human Subjects. Second, we obtained permission to conduct this study from the Union Hospital Affiliated to Fujian Medical University ethics committee (approval number: 2021WSJK028). Finally, we obtained written informed consent from all study participants. Consent for publication Not applicable. Competing interests The authors declare that they have no competing interests. References Collaborators G C R D, Prevalence and attributable health burden of chronic respiratory diseases, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017 . Lancet Respir Med, 2020,6(8): 585-596. Wang C, Xu J, Yang L, et al., Prevalence and risk factors of chronic obstructive pulmonary disease in China (the China Pulmonary Health [CPH] study): a national cross-sectional study . Lancet, 2018,10131(391): 1706-1717. Vestbo J, Anderson J A, Calverley P M, et al., Adherence to inhaled therapy, mortality and hospital admission in COPD . Thorax, 2009,11(64): 939-43. Melani A S, Bonavia M, Cilenti V, et al., Inhaler mishandling remains common in real life and is associated with reduced disease control . Respir Med, 2011,6(105): 930-8. 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Tables Table 1 Characteristics of the participants ( n =131) Demographic characteristics Subclasses N=131 Percent (%) Age < 65 64 48.85 ≥ 65 67 51.15 Gender Male 86 65.65 Female 45 34.35 Education level primary school and below 48 36.64 Junior high school and below 45 34.35 High school and above 38 29.01 Diagnosis COPD 61 46.56 asthma 58 44.27 COPD-asthma overlap syndrome 12 9.16 Personal income per month (Yuan) 10000 6 4.58 Table 2 Pharmacy Service Content Preferences Pharmacy Service Content Very interested N(%) Somewhat interested N(%) Neutral N(%) Not very interested N(%) Not interested at all N(%) Total The etiology of my disease 63(48.09%) 35(26.72%) 25(19.08%) 6(4.58%) 2(1.53%) 131 How to manage acute exacerbations 93(70.99%) 16(12.21%) 18(13.74%) 2(1.53%) 2(1.53%) 131 The purpose of the medications prescribed by my doctor 63(48.09%) 38(29.01%) 20(15.27%) 9(6.87%) 1(0.76%) 131 The duration of my medication regimen 99(75.57%) 18(13.74%) 12(9.16%) 1(0.76%) 1(0.76%) 131 The dosage, administration, and timing of my medications 117(89.31%) 8(6.11%) 5(3.82%) 1(0.76%) 0 131 Possible drug interactions with other medications I am taking 73(55.73%) 24(18.32%) 25(19.08%) 6(4.58%) 3(2.29%) 131 Common adverse reactions of the medications 72(54.96%) 21(16.03%) 33(25.19%) 4(3.05%) 1(0.76%) 131 How to exercise in daily life 79(60.13%) 19(14.50%) 24(18.32%) 8(6.11%) 1(0.76%) 131 Dietary precautions 81(61.83%) 27(20.61%) 17(12.98%) 5(3.82%) 1(0.76%) 131 Table 3 Patients' Communication Preferences When Receiving Pharmaceutical Care Pharmacy Service Communication Preferences N=131 Percent (%) When being informed about disease and medication-related knowledge I expect pharmacists to highlight key points 72 54.96 I expect pharmacists to provide comprehensive information 59 45.04 When pharmacists inform me about disease and medication-related knowledge, I prefer Inform me indirectly via family members 26 19.85 Provide indirect information through written materials (e.g., popular science articles, videos, brochures) 66 50.38 Communicate directly via phone or WeChat 49 37.4 Inform me face-to-face 102 77.86 What communication method do you think can help you better adhere to medical advice? Provide encouragement and support 56 42.75 Emphasize the serious consequences of non-adherence 17 12.98 Combine encouragement and warnings 58 44.27 Are you uncomfortable with stern warnings? Yes, I prefer gentler suggestions 57 43.51 No, I take pharmacists' advice more seriously 74 56.49 Table 4 Evaluation of pharmacy services Item Strongly Agree N(%) Agree N(%) Neutral N(%) Disagree N(%) Strongly Disagree N(%) I am satisfied with the pharmaceutical services I have received 118(90.08%) 11(8.40%) 2(1.53%) 0 0 Pharmaceutical services are important for my disease management 107(81.68%) 19(14.50%) 5(3.82%) 0 0 I am willing to accept treatment advice and guidance from pharmacists 10(79.39%) 19(14.50%) 6(4.58%) 2(1.53%) 0 I can master disease and medication knowledge provided by pharmacists and apply it to daily self-management 96(73.28%) 24(18.32%) 9(6.87%) 2(1.53%) 0 Pharmaceutical services enhance my understanding of my disease 103(78.63%) 21(16.03%) 7(5.34%) 0 0 Pharmaceutical services help resolve medication confusion and prevent medication errors 106(80.92%) 21(16.03%) 4(3.05%) 0 0 Pharmacist supervision and guidance improve my medication adherence (timely, as prescribed), enhancing treatment effectiveness 105(80.15%) 19(14.50%) 5(3.82% 2(1.53%) 0 I would seek pharmacist help again for future medication issues 110(83.97%) 13(9.92%) 5(3.82%) 3(2.29%) 0 I would recommend pharmacists to others if needed 101(77.10%) 18(13.74%) 8(6.11%) 4(3.05%) 0 I am willing to accept pharmaceutical services during hospitalization if offered by pharmacists 104(79.39%) 14(10.69%) 10(7.63%) 2(1.53%) 1(0.76%) I am willing to pay 30 RMB per visit for pharmacy clinic services (covered by health insurance) 108(82.44%) 10(7.63%) 5(3.82%) 6(4.58%) 2(1.53%) Additional Declarations No competing interests reported. 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00:38:08","currentVersionCode":1,"declarations":"","doi":"10.21203/rs.3.rs-6702396/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-6702396/v1","draftVersion":[],"editorialEvents":[],"editorialNote":"","failedWorkflow":false,"files":[{"id":84304349,"identity":"df9c34f7-34f5-4c12-ac32-334bafa21811","added_by":"auto","created_at":"2025-06-10 11:23:04","extension":"png","order_by":1,"title":"Figure 1","display":"","copyAsset":false,"role":"figure","size":59630,"visible":true,"origin":"","legend":"\u003cp\u003ePatients' knowledge of disease and medication (\u003cem\u003en\u003c/em\u003e=131)\u003c/p\u003e","description":"","filename":"1.png","url":"https://assets-eu.researchsquare.com/files/rs-6702396/v1/592bd8e661fd7869c3bd134a.png"},{"id":84304341,"identity":"db08c6aa-544e-4e18-9d2e-c5f423bbf893","added_by":"auto","created_at":"2025-06-10 11:23:03","extension":"png","order_by":2,"title":"Figure 2","display":"","copyAsset":false,"role":"figure","size":51397,"visible":true,"origin":"","legend":"\u003cp\u003eInfluence of advertising\u003c/p\u003e","description":"","filename":"2.png","url":"https://assets-eu.researchsquare.com/files/rs-6702396/v1/cf7a585a3fb6080fc12677da.png"},{"id":109704690,"identity":"de928c26-3e24-42c0-aecb-407620744c89","added_by":"auto","created_at":"2026-05-21 11:26:11","extension":"pdf","order_by":0,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":361682,"visible":true,"origin":"","legend":"","description":"","filename":"manuscript.pdf","url":"https://assets-eu.researchsquare.com/files/rs-6702396/v1/82c439f7-3a97-453f-8426-e91497af9d13.pdf"},{"id":84304364,"identity":"866411cd-898b-4998-88fd-418ad6339afc","added_by":"auto","created_at":"2025-06-10 11:23:04","extension":"docx","order_by":0,"title":"","display":"","copyAsset":false,"role":"supplement","size":22697,"visible":true,"origin":"","legend":"","description":"","filename":"supplementaryfileQuestionnaire.docx","url":"https://assets-eu.researchsquare.com/files/rs-6702396/v1/a22f2afd14db223274d3427c.docx"}],"financialInterests":"No competing interests reported.","formattedTitle":"Pharmaceutical care needs of patients with chronic respiratory diseases：results from a cross sectional study","fulltext":[{"header":"Introduction","content":"\u003cp\u003eChronic airway diseases (CADs) are a group of chronic diseases characterised by airway inflammation and airflow limitation, mainly including chronic obstructive pulmonary disease (COPD) and bronchial asthma. According to the Global Burden of Disease Study, COPD has become the third leading cause of death in the world [1], and the prevalence of COPD in people over 40 years of age in China is as high as 13.7% [2], representing a large patient base and a heavy disease burden. The disease is characterised by a long disease course, recurrent acute exacerbations and the need for long-term medication, and patients must continue to use inhalers and oral medications to control symptoms and slow the decline in lung function. However, studies have shown that patients with chronic respiratory diseases generally have low medication adherence (approximately 30-50%) [3], an 80% error rate in the use of inhalers [4], and a serious lack of disease knowledge and self-management skills, leading to poor disease control, frequent acute exacerbations and increased healthcare costs.\u003c/p\u003e\n\u003cp\u003eIn recent years, with the deepening of the concept of \u0026apos;patient-centred\u0026apos; medical services, pharmacy services have gradually shifted from traditional drug supply to more sophisticated and individualised medication management. Studies have shown that pharmacist-led pharmacy interventions, such as inhaler technique instruction, medication adherence education, and adverse drug reaction monitoring, can significantly improve patients\u0026apos; clinical outcomes \u003csup\u003e[5, 6]\u003c/sup\u003e. However, the existing pharmacy service model focuses mainly on the treatment phase of the disease and pays insufficient attention to long-term follow-up, health empowerment and the diverse needs of patients, such as psychological support and alleviation of economic burden\u003csup\u003e[7]\u003c/sup\u003e. In addition, the pharmacy service needs of patients with chronic respiratory diseases in China have not been systematically studied, and there is a mismatch between the service content and the actual needs of patients, which limits the accurate implementation of pharmacy services.\u003c/p\u003e\n\u003cp\u003eTherefore, this study aims to systematically analyse the current situation and factors influencing the demand for pharmacy services among patients with chronic respiratory diseases through a cross-sectional survey, and to explore patients\u0026apos; core needs for medication counseling and disease management services to provide an evidence-based basis for optimising the pharmacy service model and improving patients\u0026apos; health outcomes. The results of this study will also help promote the prevention and treatment of chronic respiratory diseases in the framework of the \u0026quot;Healthy China 2030\u0026quot; plan, and provide a reference for the rational allocation of resources in the charging policy for pharmacy services.\u003c/p\u003e"},{"header":"Methods","content":"\u003cp\u003e\u003cstrong\u003eStudy design and participants\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThis hospital-based cross-sectional study was conducted at the Affiliated Union Hospital of Fujian Medical University in Fujian Province, China, from June to August 2024. We used a self-developed questionnaire to assess the pharmaceutical care needs of patients with chronic respiratory diseases, including chronic obstructive pulmonary disease, asthma, and COPD-asthma overlap syndrome. The study protocol received ethical approval from the institutional review board.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eSurvey instrument and implementation\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThe \u0026quot;Questionnaire on Pharmaceutical Care Services for Patients with Chronic Airway Diseases\u0026quot; consists of three sections. Section one includes 7 questions on patients\u0026apos; basic information, such as age, sex, disease type, smoking status, education level, and income. Section two concerns patients\u0026apos; needs and preferences for pharmaceutical care services. This part is further divided into four subsections, consisting of 25 questions, such as 4 questions assessing patients\u0026apos; knowledge of their disease, 10 questions on content preferences, 4 on expression preferences and 7 questions about the influence of publicity, particularly how patients learned about the outpatient pharmacy. Section three includes 11 questions evaluating the pharmacy services provided by the outpatient pharmacy. The second section ( Disease and Medication Cognition and Content Preferences) and the third section use a five - point Likert - type scale (1 = strongly disagree / not interested at all, 2 = disagree / not very interested, 3 = neutral, 4 = agree / interested, 5 = strongly agree / very interested) for data collection. Detailed information can be found in the supplementary file.\u003c/p\u003e\n\u003cp\u003eIn this study, data were collected via paper questionnaires completed by chronic airway disease patients at our pharmacy clinic. After unified training, outpatient pharmacists distributed the questionnaires, explained their purpose to eligible patients, instructed participants to complete them upon understanding, and collected the questionnaires on-site.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eStatistical analysis\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThe returned questionnaires were uniformly numbered. Two individuals entered the data. We collated all the collected data using Microsoft Excel 2019 and, after checking for errors, imported the data into SPSS 26.0 software for statistical analysis. We described the characteristics of participants, patients\u0026apos; pharmaceutical care service preferences, and the influence of publicity using frequencies and percentages. As for patients\u0026apos; knowledge of their disease and medication use, we used a bar chart for illustration. Count data were expressed as the number of cases (%). \u003c/p\u003e"},{"header":"Results","content":"\u003cp\u003e\u003cstrong\u003eCharacteristics of the participants\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eIn this study, 157 patients with chronic airway disease visited the pharmacy clinic between June and August 2024, of whom 131 completed the questionnaire, yielding an 83.43% response rate. The patients\u0026apos; ages ranged from 18 to 85 years, and the majority were male, accounting for 65.65% of the participants. The educational level of the participants was predominantly low, with 70.99% having junior high school education or below. In terms of disease distribution, COPD was the most common condition, affecting 46.56% of the patients, followed by asthma at 44.27%. Further demographic details are outlined in Table 1.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003ePatients\u0026apos; knowledge of disease and medication\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003ePatients exhibited notable differences in their understanding of disease management and medication. A substantial 97.71% agreed, to some extent, that \u0026quot;the right medication can control symptoms well,\u0026quot; with over half (51.91%) strongly endorsing this view. However, a significant portion (54.20%) also acknowledged that \u0026quot;it is OK not to take medication sometimes\u0026quot;. Furthermore, concerns over long-term medication were prevalent, with 56.48% of patients worried about potential harm to the body and drug dependence. These findings are elaborated in Fig.1.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003ePreferences for pharmacy services\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003ePatients\u0026apos; preferences for pharmacy services centred on disease knowledge, medication advice, and self-management skills. Specifically, 89.31% were highly interested in medication usage and dosage, 75.57% in the duration of medication regimen, and 70.99% in acute attack management. Additionally, over 60% of patients showed strong interest in dietary contraindications and\u0026nbsp;exercise advice, indicating a significant demand for self-management knowledge. These details are illustrated in Table 2.\u003c/p\u003e\n\u003cp\u003ePatients had distinct preferences regarding communication styles and adherence strategies. The majority (77.86%) favored \u0026quot;face-to-face communication\u0026quot; for disease and medication information, while 54.96% preferred pharmacists to \u0026quot;focus on key points\u0026quot; rather than detailed explanations. When it came to improving medication adherence, 44.27% found the \u0026quot;combination of encouragement and reminders\u0026quot; most effective. Interestingly, 56.49% did not object to \u0026quot;stern warnings,\u0026quot; indicating a tolerance for direct advice. These preferences highlight the need for personalized communication approaches in pharmacy services. (Table 3)\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eInfluence of advertising\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003ePatients\u0026apos; acceptance of pharmacy services was predominantly driven by recommendations from their attending physicians (90.08%), which was significantly more influential than social media recommendations (52.67%) or peer recommendations from other patients (16.03%). These latter two channels had substantially lower influence. (Figure 2)\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eEvaluation of pharmacy services\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThe pharmacy service received high satisfaction from patients, with 90.08% expressing satisfaction. A significant majority (81.68%) acknowledged its importance for disease management, and 83.97% indicated a willingness to continue seeking help from pharmacists. However, a small percentage of patients (3.05% to 6.11%) had reservations about the service\u0026apos;s effectiveness. The data also showed strong patient agreement with the pharmacist\u0026apos;s role in treatment advice and guidance (79.39%), and most patients (73.28%) felt they could apply the knowledge provided for self-management. Additionally, 80.15% believed the service improved medication adherence and treatment outcomes. (Table 4)\u003c/p\u003e"},{"header":"Discussion","content":"\u003cp\u003eThis study revealed that while most patients acknowledge the importance of correct medication use, concerns about the safety of long-term medication use and dependence are significant. For instance, 54.20% of patients agreed to varying degrees that 'it's okay if I occasionally don’t take medication for my illness', which aligns with the low adherence reported by Vestbo et al. [3]. The issue of medication adherence in patients with chronic respiratory diseases is a complex and pervasive challenge. Studies have shown that pharmacy services can play an important role in improving patients' medication adherence \u003csup\u003e[8-11]\u003c/sup\u003e. Through pharmacy services, pharmacists can provide patients with personalised medication advice and education, which can improve patients' knowledge and understanding of medications and thus improve medication adherence \u003csup\u003e[12]\u003c/sup\u003e. In patients with chronic obstructive pulmonary disease (COPD), pharmacy service interventions have been shown to significantly improve patients' medication adherence and health-related knowledge \u003csup\u003e[13-15]\u003c/sup\u003e. Pharmacist education and management increased patients' knowledge of their disease and confidence in their medication, which contributed to reduced hospitalisation rates and improved overall health \u003csup\u003e[12, 16, 17]\u003c/sup\u003e. In addition, pharmacy services can help physicians understand patients' medication use by providing a feedback mechanism to adjust treatment regimens to improve patient adherence. Studies have shown that providing feedback to physicians on patient medication use can facilitate physician-patient communication and improve the medication management process, and although the direct impact of this feedback mechanism on medication adherence and patient health outcomes may be limited, it is potentially valuable in improving healthcare delivery processes \u003csup\u003e[18]\u003c/sup\u003e. In conclusion, improving patient knowledge and adherence to medication through pharmacy services not only improves health outcomes for patients with chronic respiratory disease, but also effectively reduces healthcare resource use and associated healthcare costs \u003csup\u003e[19]\u003c/sup\u003e.\u003c/p\u003e\n\u003cp\u003eA significant proportion of patients, over 50%, express a desire for pharmacists to offer post-pharmacy health education materials. These materials, which include popular science articles, videos, and disease science brochures, can help patients enhance their health literacy, correct misconceptions, and expand their knowledge of diseases \u003csup\u003e[5]\u003c/sup\u003e. Studies have shown that the readability and understandability of patient education materials are crucial for improving patient adherence \u003csup\u003e[20, 21]\u003c/sup\u003e. Simplifying these materials is a key strategy to boost patient knowledge and adherence. For instance, a study assessing asthma patient education materials found that many were written above the recommended sixth-grade reading level, potentially hindering patients' understanding and adherence to treatment recommendations \u003csup\u003e[22]\u003c/sup\u003e. Moreover, combining audiovisual media, such as scientific videos, has proven effective in enhancing patient awareness \u003csup\u003e[23-25]\u003c/sup\u003e. Video, as an educational tool, offers the benefits of low cost and rapid dissemination, making it highly applicable for chronic disease management and learning \u003csup\u003e[26]\u003c/sup\u003e. In a randomised clinical trial, researchers compared the effects of infographics and videos on medication adherence in asthma patients and showed that both formats improved adherence, but infographics may have a longer-term advantage as they don't require devices \u003csup\u003e[27]\u003c/sup\u003e.\u003c/p\u003e\n\u003cp\u003ePharmacy service needs of patients follow a hierarchical structure. Basic needs, such as \u0026nbsp; medication administration guidance, are prioritised over higher-order needs, such as drug interaction information. This is consistent with the findings of Melani et al. [4], who highlighted the \"high error rate in the use of inhaler devices\" among patients. Their research underscores the necessity for pharmacists to first address technical difficulties before progressively incorporating comprehensive disease management strategies. In practical terms, this stratified approach ensures that patients receive the most essential support first. By prioritising basic needs, pharmacists can correct fundamental misunderstandings and ensure proper medication use, which is vital for treatment efficacy and patient safety. Pharmacists can significantly improve treatment outcomes by spending time demonstrating correct inhaler techniques and allowing patients to practice under their supervision. Furthermore, patients' significant concerns about 'exercise advice' (60.13%) and 'diet management' (61.83%) highlight the multifaceted nature of chronic disease management \u003csup\u003e[7]\u003c/sup\u003e.The notable percentage of patients concerned about these aspects reflects growing patient recognition of health's holistic nature. \u0026nbsp;Chronic disease management involves not only medication but also lifestyle adjustments to complement medical treatments. Pharmacists can collaborate with other healthcare professionals, such as dietitians and physical therapists, to develop comprehensive care plans integrating these various aspects. This multidisciplinary approach not only enhances patient satisfaction but also leads to better long-term health outcomes by addressing the full spectrum of patient needs.\u003c/p\u003e\n\u003cp\u003ePatients exhibit distinct preferences regarding communication methods with pharmaceutical service providers. Our data reveal that patients favor face - to - face communication (77.86%) and targeted messaging (54.96%). This aligns with Baggott et al.'s \u003csup\u003e[7]\u003c/sup\u003e \"personalized communication\" concept in pharmaceutical services, which stresses adapting communication strategies to individual patients. Notably, 19.85% of patients still get information indirectly through family members, which might be due to low patient literacy or language barriers. This indicates that in pharmaceutical services, the actual situations of patients and their family members should be considered, and the \"family - participatory education\" concept should be explored, particularly for elderly patients or those with low education. Moreover, remote consulting via WeChat and other platforms can supplement face - to - face communication, further enhancing the accessibility and convenience of pharmaceutical services \u003csup\u003e[6]\u003c/sup\u003e.\u003c/p\u003e\n\u003cp\u003eIn China, pharmacy clinics are a new concept for patients, requiring a process of acceptance. Currently, patients' acceptance of pharmacy services is mainly driven by the recommendation of attending physicians, with a recommendation rate of up to 90.08%. This shows that attending physicians' opinions are crucial in patients' decision-making regarding pharmacy services. In contrast, social media's influence, at 52.67%, is relatively limited, indicating that pharmacy service promotion still heavily depends on in-hospital channels. However, with technological advancements and shifting information dissemination patterns, it is necessary to explore more effective promotion models. Future strategies could include multi-dimensional approaches. For example, joint patient education activities with community health organizations can utilize their resources and influence to reach more patients. Additionally, spreading popular science content via short - video platforms, which have a large user base and strong dissemination power, can help popularize pharmacy knowledge and services among the general public. These methods can increase the visibility of pharmacy services, improve patients' understanding and acceptance, and ultimately promote the development and application of pharmacy clinics.\u003c/p\u003e\n\u003cp\u003eWhile patient satisfaction with current pharmacy services is high (90.08%), a notable minority (3.05% - 6.11%) express doubts regarding service effectiveness. These findings suggest that despite overall positive perceptions, there remains room for improvement and innovation pharmacy in care delivery. To address these concerns, future directions could involve exploring diversified service models supported by health insurance policies. Such models could include long-term follow-up programs to monitor patient progress and medication adherence. Additionally, health empowerment initiatives could provide patients with more knowledge and tools for self-management. Establishing a collaborative pharmacist-patient management mechanism is another valuable opportunity. This approach would facilitate active engagement between healthcare providers and patients, potentially leading to better health outcomes through personalized care plans and ongoing communication.\u003c/p\u003e"},{"header":"Conclusion","content":"\u003cp\u003eThis cross - sectional study analysed the pharmaceutical care needs of 131 patients with chronic airway diseases (CADs) at a tertiary hospital in Fujian Province from June to August 2024.\u0026nbsp;Results showed patients' core needs were medication guidance (89.31%),\u0026nbsp;disease knowledge (including medication duration (75.57%) and management of acute exacerbations (70.99%)) , and self - management skills (over 60%).\u0026nbsp;Most patients (77.86%) preferred face - to - face communication, and 54.96% wanted pharmacists to highlight key information.\u0026nbsp;Despite 90.08% satisfaction with pharmaceutical services, many patients (56.48%) had varying degrees of concern about the long-term safety of medication. Most patients (90.08%) were driven to seek services by their physicians' recommendations, while social media had limited influence.\u0026nbsp;Pharmaceutical services should prioritise technical issues like inhaler use and integrate educational materials, family involvement, and multidisciplinary resources to meet diverse needs.\u0026nbsp;Future efforts should focus on optimising service models, enhancing promotion, and securing policy support to improve the precision of pharmaceutical care and support chronic respiratory disease management goals.\u003c/p\u003e"},{"header":"Abbreviations","content":"\u003cdiv class=\"DefinitionList\"\u003e \u003cdiv class=\"DefinitionListEntry\"\u003e \u003cdiv class=\"Term\"\u003eCADs\u003c/div\u003e \u003cdiv class=\"Description\"\u003e \u003cp\u003eChronic Airway Diseases\u003c/p\u003e \u003c/div\u003e \u003c/div\u003e \u003cdiv class=\"DefinitionListEntry\"\u003e \u003cdiv class=\"Term\"\u003eCOPD\u003c/div\u003e \u003cdiv class=\"Description\"\u003e \u003cp\u003eChronic Obstructive Pulmonary Disease.\u003c/p\u003e \u003c/div\u003e \u003c/div\u003e \u003c/div\u003e"},{"header":"Declarations","content":"\u003cp\u003e\u003cstrong\u003eAcknowledgements\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eNot applicable.\u0026nbsp;\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eConflicts of interest\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThere are no conficts of interest declared.\u0026nbsp;\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eAuthors\u0026rsquo; contributions\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eQuestionnaire Design: Jin Zhang, Qi Lin, Maobai Liu, Muying Yang; Methodology: Jin Zhang, Muying Yang; Questionnaire Administration: Jin Zhang, Shuiqing Zhang, Yingying Li; Data Organization and Analysis: Jin Zhang, Shuiqing Zhang, Qi Lin; Writing - original draft preparation: Jin Zhang; Writing - review and editing: Jin Zhang, Qi Lin, Maobai Liu, Muying Yang. All authors read and approved the final manuscript.\u0026nbsp;\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eFunding\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eProvincial key Clinical Department of Fujian Province (0802713)\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eAvailability of data and materials\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThe datasets used and analysed during the current study are available from the corresponding author on reasonable request.\u0026nbsp;\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eEthics approval and consent to participate\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eFirst, we followed the Declaration of Helsinki Ethics Principles for Medical Research Involving Human Subjects. Second, we obtained permission to conduct this study from the Union Hospital Affiliated to Fujian Medical University ethics committee (approval number: 2021WSJK028). Finally, we obtained written informed consent from all study participants.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eConsent for publication\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eNot applicable.\u0026nbsp;\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eCompeting interests\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThe authors declare that they have no competing interests.\u0026nbsp;\u003c/p\u003e"},{"header":"References","content":"\u003col\u003e\n \u003cli\u003eCollaborators G C R D, Prevalence and attributable health burden of chronic respiratory diseases, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017\u003cem\u003e.\u003c/em\u003e Lancet Respir Med, 2020,6(8): 585-596.\u003c/li\u003e\n \u003cli\u003eWang C, Xu J, Yang L, et al., Prevalence and risk factors of chronic obstructive pulmonary disease in China (the China Pulmonary Health [CPH] study): a national cross-sectional study\u003cem\u003e.\u003c/em\u003e Lancet, 2018,10131(391): 1706-1717.\u003c/li\u003e\n \u003cli\u003eVestbo J, Anderson J A, Calverley P M, et al., Adherence to inhaled therapy, mortality and hospital admission in COPD\u003cem\u003e.\u003c/em\u003e Thorax, 2009,11(64): 939-43.\u003c/li\u003e\n \u003cli\u003eMelani A S, Bonavia M, Cilenti V, et al., Inhaler mishandling remains common in real life and is associated with reduced disease control\u003cem\u003e.\u003c/em\u003e Respir Med, 2011,6(105): 930-8.\u003c/li\u003e\n \u003cli\u003eGangadharan A, Thomas D S, Harshida, et al., The Role of Clinical Pharmacist in Enhancement of Medication Adherence and Quality of Life in Bronchial Asthma and Chronic Obstructive Pulmonary Disease\u003cem\u003e.\u003c/em\u003e Journal of Drug Delivery \u0026amp; Therapeutics, 2021,11):\u003c/li\u003e\n \u003cli\u003eZhang J, Lin Q, Liu M, et al., SWOT Analysis of Chronic Airway Disease Management in Drug Treatment Clinic in the Context of Medical Insurance Payment Reform\u003cem\u003e.\u003c/em\u003e Chin J Mod Appl Pharm, 2024,10(41): 1422-1427.\u003c/li\u003e\n \u003cli\u003eBaggott C, Chan A, Hurford S, et al., Patient preferences for asthma management: a qualitative study\u003cem\u003e.\u003c/em\u003e BMJ open, 2020,8(10): e037491.\u003c/li\u003e\n \u003cli\u003eKini V and Ho P M, Interventions to Improve Medication Adherence: A Review\u003cem\u003e.\u003c/em\u003e Jama, 2018,23(320): 2461-2473.\u003c/li\u003e\n \u003cli\u003eViswanathan M, Golin C E, Jones C D, et al., Interventions to improve adherence to self-administered medications for chronic diseases in the United States: a systematic review\u003cem\u003e.\u003c/em\u003e Ann Intern Med, 2012,11(157): 785-95.\u003c/li\u003e\n \u003cli\u003eZobell J T, Schwab E, Collingridge D S, et al., Impact of pharmacy services on cystic fibrosis medication adherence\u003cem\u003e.\u003c/em\u003e Pediatr Pulmonol, 2017,8(52): 1006-1012.\u003c/li\u003e\n \u003cli\u003eHesso I, Gebara S N and Kayyali R, Impact of community pharmacists in COPD management: Inhalation technique and medication adherence\u003cem\u003e.\u003c/em\u003e Respir Med, 2016,118): 22-30.\u003c/li\u003e\n \u003cli\u003eJarab A S, Alqudah S G, Khdour M, et al., Impact of pharmaceutical care on health outcomes in patients with COPD\u003cem\u003e.\u003c/em\u003e Int J Clin Pharm, 2012,1(34): 53-62.\u003c/li\u003e\n \u003cli\u003eJia X, Zhou S, Luo D, et al., Effect of pharmacist-led interventions on medication adherence and inhalation technique in adult patients with asthma or COPD: A systematic review and meta-analysis\u003cem\u003e.\u003c/em\u003e J Clin Pharm Ther, 2020,5(45): 904-917.\u003c/li\u003e\n \u003cli\u003eMilosavljevic A, Aspden T and Harrison J, Community pharmacist-led interventions and their impact on patients\u0026apos; medication adherence and other health outcomes: a systematic review\u003cem\u003e.\u003c/em\u003e Int J Pharm Pract, 2018,5(26): 387-397.\u003c/li\u003e\n \u003cli\u003eApikoglu-Rabus S, Yesilyaprak G and Izzettin F V, Drug-related problems and pharmacist interventions in a cohort of patients with asthma and chronic obstructive pulmonary disease\u003cem\u003e.\u003c/em\u003e Respir Med, 2016,120): 109-115.\u003c/li\u003e\n \u003cli\u003eAlabkal R M, Medlinskiene K, Silcock J, et al., Impact of Pharmacist-Led Interventions to Improve Clinical Outcomes for Adults With Type 2 Diabetes at Risk of Developing Cardiovascular Disease: A Systematic Review and Meta-analysis\u003cem\u003e.\u003c/em\u003e J Pharm Pract, 2023,4(36): 888-899.\u003c/li\u003e\n \u003cli\u003eNewman T V, San-Juan-Rodriguez A, Parekh N, et al., Impact of community pharmacist-led interventions in chronic disease management on clinical, utilization, and economic outcomes: An umbrella review\u003cem\u003e.\u003c/em\u003e Res Social Adm Pharm, 2020,9(16): 1155-1165.\u003c/li\u003e\n \u003cli\u003eZaugg V, Korb-Savoldelli V, Durieux P, et al., Providing physicians with feedback on medication adherence for people with chronic diseases taking long-term medication\u003cem\u003e.\u003c/em\u003e Cochrane Database Syst Rev, 2018,1(1): Cd012042.\u003c/li\u003e\n \u003cli\u003ede Bittner M R and Zaghab R W, Improving the lives of patients with chronic diseases: pharmacists as a solution\u003cem\u003e.\u003c/em\u003e J Health Care Poor Underserved, 2011,2(22): 429-36.\u003c/li\u003e\n \u003cli\u003eReligioni U, Barrios-Rodr\u0026iacute;guez R, Requena P, et al., Enhancing Therapy Adherence: Impact on Clinical Outcomes, Healthcare Costs, and Patient Quality of Life\u003cem\u003e.\u003c/em\u003e Medicina (Kaunas), 2025,1(61):\u003c/li\u003e\n \u003cli\u003eMart\u0026iacute;nez-Riera J R, Aviles Gonzalez C I, Zambrano Bermeo R N, et al., Educational Strategies to Promote Adherence to Treatment in Patients with Cardiovascular Disease\u003cem\u003e.\u003c/em\u003e Int J Environ Res Public Health, 2022,16(19):\u003c/li\u003e\n \u003cli\u003ePhua C Y, Zheng L, Tan N C, et al., Review of the quality of printed patient education materials on asthma available in primary care in Singapore\u003cem\u003e.\u003c/em\u003e J Asthma, 2020,7(57): 787-798.\u003c/li\u003e\n \u003cli\u003eMonteiro Grilo A, Ferreira A C, Pedro Ramos M, et al., Effectiveness of educational videos on patient\u0026apos;s preparation for diagnostic procedures: Systematic review and Meta-Analysis\u003cem\u003e.\u003c/em\u003e Prev Med Rep, 2022,28): 101895.\u003c/li\u003e\n \u003cli\u003eCiciriello S, Johnston R V, Osborne R H, et al., Multimedia educational interventions for consumers about prescribed and over-the-counter medications\u003cem\u003e.\u003c/em\u003e Cochrane Database Syst Rev, 2013,4(2013): Cd008416.\u003c/li\u003e\n \u003cli\u003eMoe-Byrne T, Evans E, Benhebil N, et al., The effectiveness of video animations as information tools for patients and the general public: A systematic review\u003cem\u003e.\u003c/em\u003e Front Digit Health, 2022,4): 1010779.\u003c/li\u003e\n \u003cli\u003eNavarro O, Escriv\u0026aacute; M, Faubel R, et al., Empowering Patients Living With Chronic Conditions Using Video as an Educational Tool: Scoping Review\u003cem\u003e.\u003c/em\u003e J Med Internet Res, 2021,7(23): e26427.\u003c/li\u003e\n \u003cli\u003eEbrahimabadi M, Rezaei K, Moini A, et al., Infographics or video; which one is more effective in asthmatic patients\u0026apos; health? a randomized clinical trial\u003cem\u003e.\u003c/em\u003e J Asthma, 2019,12(56): 1306-1313.\u003c/li\u003e\n\u003c/ol\u003e"},{"header":"Tables","content":"\u003cp\u003e\u003cstrong\u003eTable 1\u003c/strong\u003e Characteristics of the participants (\u003cem\u003en\u003c/em\u003e=131)\u003c/p\u003e\n\u003ctable border=\"1\" cellspacing=\"0\" cellpadding=\"0\" width=\"658\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 211px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eDemographic characteristics\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 198px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eSubclasses\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 124px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eN=131\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 124px;\"\u003e\n \u003cp\u003e\u003cstrong\u003ePercent (%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd rowspan=\"2\" style=\"width: 211px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eAge\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 198px;\"\u003e\n \u003cp\u003e\u0026lt; 65\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 124px;\"\u003e\n \u003cp\u003e64\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 124px;\"\u003e\n \u003cp\u003e48.85\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 198px;\"\u003e\n \u003cp\u003e\u0026ge; 65\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 124px;\"\u003e\n \u003cp\u003e67\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 124px;\"\u003e\n \u003cp\u003e51.15\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd rowspan=\"2\" style=\"width: 211px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eGender\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 198px;\"\u003e\n \u003cp\u003eMale\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 124px;\"\u003e\n \u003cp\u003e86\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 124px;\"\u003e\n \u003cp\u003e65.65\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 198px;\"\u003e\n \u003cp\u003eFemale\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 124px;\"\u003e\n \u003cp\u003e45\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 124px;\"\u003e\n \u003cp\u003e34.35\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd rowspan=\"3\" style=\"width: 211px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eEducation level\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 198px;\"\u003e\n \u003cp\u003eprimary school and below\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 124px;\"\u003e\n \u003cp\u003e48\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 124px;\"\u003e\n \u003cp\u003e36.64\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 198px;\"\u003e\n \u003cp\u003eJunior high school and below\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 124px;\"\u003e\n \u003cp\u003e45\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 124px;\"\u003e\n \u003cp\u003e34.35\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 198px;\"\u003e\n \u003cp\u003eHigh school and above\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 124px;\"\u003e\n \u003cp\u003e38\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 124px;\"\u003e\n \u003cp\u003e29.01\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd rowspan=\"3\" style=\"width: 211px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eDiagnosis\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 198px;\"\u003e\n \u003cp\u003eCOPD\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 124px;\"\u003e\n \u003cp\u003e61\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 124px;\"\u003e\n \u003cp\u003e46.56\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 198px;\"\u003e\n \u003cp\u003easthma\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 124px;\"\u003e\n \u003cp\u003e58\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 124px;\"\u003e\n \u003cp\u003e44.27\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 198px;\"\u003e\n \u003cp\u003eCOPD-asthma overlap syndrome\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 124px;\"\u003e\n \u003cp\u003e12\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 124px;\"\u003e\n \u003cp\u003e9.16\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd rowspan=\"5\" style=\"width: 211px;\"\u003e\n \u003cp\u003e\u003cstrong\u003ePersonal income per month (Yuan)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 198px;\"\u003e\n \u003cp\u003e\u0026lt; 1000\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 124px;\"\u003e\n \u003cp\u003e49\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 124px;\"\u003e\n \u003cp\u003e37.40\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 198px;\"\u003e\n \u003cp\u003e1000-2999\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 124px;\"\u003e\n \u003cp\u003e29\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 124px;\"\u003e\n \u003cp\u003e22.14\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 198px;\"\u003e\n \u003cp\u003e3000-4999\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 124px;\"\u003e\n \u003cp\u003e27\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 124px;\"\u003e\n \u003cp\u003e20.61\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 198px;\"\u003e\n \u003cp\u003e5000-10000\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 124px;\"\u003e\n \u003cp\u003e20\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 124px;\"\u003e\n \u003cp\u003e15.27\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 198px;\"\u003e\n \u003cp\u003e\u0026gt; 10000\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 124px;\"\u003e\n \u003cp\u003e6\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 124px;\"\u003e\n \u003cp\u003e4.58\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp\u003e\u003cstrong\u003eTable 2\u003c/strong\u003e Pharmacy Service Content Preferences\u003c/p\u003e\n\u003cdiv align=\"Left\"\u003e\n \u003ctable border=\"1\" cellspacing=\"0\" cellpadding=\"0\" width=\"761\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 194px;\"\u003e\n \u003cp\u003e\u003cstrong\u003ePharmacy Service Content\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eVery interested\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003eN(%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eSomewhat interested\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003eN(%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eNeutral\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003eN(%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eNot very interested\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003eN(%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eNot interested at all\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003eN(%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 67px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eTotal\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 194px;\"\u003e\n \u003cp\u003eThe etiology of my disease\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e63(48.09%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e35(26.72%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e25(19.08%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e6(4.58%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e2(1.53%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 67px;\"\u003e\n \u003cp\u003e131\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 194px;\"\u003e\n \u003cp\u003eHow to manage acute exacerbations\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e93(70.99%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e16(12.21%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e18(13.74%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e2(1.53%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e2(1.53%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 67px;\"\u003e\n \u003cp\u003e131\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 194px;\"\u003e\n \u003cp\u003eThe purpose of the medications prescribed by my doctor\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e63(48.09%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e38(29.01%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e20(15.27%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e9(6.87%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e1(0.76%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 67px;\"\u003e\n \u003cp\u003e131\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 194px;\"\u003e\n \u003cp\u003eThe duration of my medication regimen\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e99(75.57%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e18(13.74%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e12(9.16%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e1(0.76%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e1(0.76%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 67px;\"\u003e\n \u003cp\u003e131\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 194px;\"\u003e\n \u003cp\u003eThe dosage, administration, and timing of my medications\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e117(89.31%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e8(6.11%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e5(3.82%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e1(0.76%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 67px;\"\u003e\n \u003cp\u003e131\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 194px;\"\u003e\n \u003cp\u003ePossible drug interactions with other medications I am taking\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e73(55.73%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e24(18.32%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e25(19.08%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e6(4.58%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e3(2.29%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 67px;\"\u003e\n \u003cp\u003e131\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 194px;\"\u003e\n \u003cp\u003eCommon adverse reactions of the medications\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e72(54.96%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e21(16.03%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e33(25.19%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e4(3.05%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e1(0.76%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 67px;\"\u003e\n \u003cp\u003e131\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 194px;\"\u003e\n \u003cp\u003eHow to exercise in daily life\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e79(60.13%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e19(14.50%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e24(18.32%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e8(6.11%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e1(0.76%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 67px;\"\u003e\n \u003cp\u003e131\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 194px;\"\u003e\n \u003cp\u003eDietary precautions\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e81(61.83%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e27(20.61%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e17(12.98%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e5(3.82%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 87px;\"\u003e\n \u003cp\u003e1(0.76%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 67px;\"\u003e\n \u003cp\u003e131\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n \u003c/table\u003e\n\u003c/div\u003e\n\u003cp\u003e\u003cstrong\u003eTable 3\u003c/strong\u003e Patients\u0026apos; Communication Preferences When Receiving Pharmaceutical Care\u003c/p\u003e\n\u003ctable border=\"0\" cellspacing=\"0\" cellpadding=\"0\" width=\"694\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 522px;\"\u003e\n \u003cp\u003e\u003cstrong\u003ePharmacy Service Communication Preferences\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 81px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eN=131\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92px;\"\u003e\n \u003cp\u003e\u003cstrong\u003ePercent (%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd colspan=\"3\" style=\"width: 694px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eWhen being informed about disease and medication-related knowledge\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 522px;\"\u003e\n \u003cp\u003eI expect pharmacists to highlight key points\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 81px;\"\u003e\n \u003cp\u003e72\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92px;\"\u003e\n \u003cp\u003e54.96\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 522px;\"\u003e\n \u003cp\u003eI expect pharmacists to provide comprehensive information\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 81px;\"\u003e\n \u003cp\u003e59\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92px;\"\u003e\n \u003cp\u003e45.04\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd colspan=\"3\" style=\"width: 694px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eWhen pharmacists inform me about disease and medication-related knowledge, I prefer\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 522px;\"\u003e\n \u003cp\u003eInform me indirectly via family members\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 81px;\"\u003e\n \u003cp\u003e26\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92px;\"\u003e\n \u003cp\u003e19.85\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 522px;\"\u003e\n \u003cp\u003eProvide indirect information through written materials (e.g., popular science articles,\u0026nbsp;\u003c/p\u003e\n \u003cp\u003evideos, brochures)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 81px;\"\u003e\n \u003cp\u003e66\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92px;\"\u003e\n \u003cp\u003e50.38\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 522px;\"\u003e\n \u003cp\u003eCommunicate directly via phone or WeChat\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 81px;\"\u003e\n \u003cp\u003e49\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92px;\"\u003e\n \u003cp\u003e37.4\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 522px;\"\u003e\n \u003cp\u003eInform me face-to-face\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 81px;\"\u003e\n \u003cp\u003e102\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92px;\"\u003e\n \u003cp\u003e77.86\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd colspan=\"3\" style=\"width: 694px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eWhat communication method do you think can help you better adhere to medical advice?\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 522px;\"\u003e\n \u003cp\u003eProvide encouragement and support\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 81px;\"\u003e\n \u003cp\u003e56\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92px;\"\u003e\n \u003cp\u003e42.75\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 522px;\"\u003e\n \u003cp\u003eEmphasize the serious consequences of non-adherence\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 81px;\"\u003e\n \u003cp\u003e17\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92px;\"\u003e\n \u003cp\u003e12.98\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 522px;\"\u003e\n \u003cp\u003eCombine encouragement and warnings\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 81px;\"\u003e\n \u003cp\u003e58\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92px;\"\u003e\n \u003cp\u003e44.27\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd colspan=\"3\" style=\"width: 694px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eAre you uncomfortable with stern warnings?\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 522px;\"\u003e\n \u003cp\u003eYes, I prefer gentler suggestions\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 81px;\"\u003e\n \u003cp\u003e57\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92px;\"\u003e\n \u003cp\u003e43.51\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 522px;\"\u003e\n \u003cp\u003eNo, I take pharmacists\u0026apos; advice more seriously\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 81px;\"\u003e\n \u003cp\u003e74\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 92px;\"\u003e\n \u003cp\u003e56.49\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp\u003e\u003cstrong\u003eTable 4\u0026nbsp;\u003c/strong\u003eEvaluation of pharmacy services\u003c/p\u003e\n\u003cdiv align=\"Left\"\u003e\n \u003ctable border=\"1\" cellspacing=\"0\" cellpadding=\"0\" width=\"728\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 276px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eItem\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eStrongly Agree\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003eN(%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eAgree\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003eN(%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eNeutral\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003eN(%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eDisagree\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003eN(%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eStrongly Disagree\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003eN(%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 276px;\"\u003e\n \u003cp\u003eI am satisfied with the pharmaceutical services I have received\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e118(90.08%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e11(8.40%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e2(1.53%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 276px;\"\u003e\n \u003cp\u003ePharmaceutical services are important for my disease management\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e107(81.68%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e19(14.50%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e5(3.82%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 276px;\"\u003e\n \u003cp\u003eI am willing to accept treatment advice and guidance from pharmacists\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e10(79.39%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e19(14.50%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e6(4.58%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e2(1.53%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 276px;\"\u003e\n \u003cp\u003eI can master disease and medication knowledge provided by pharmacists and apply it to daily self-management\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e96(73.28%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e24(18.32%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e9(6.87%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e2(1.53%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 276px;\"\u003e\n \u003cp\u003ePharmaceutical services enhance my understanding of my disease\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e103(78.63%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e21(16.03%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e7(5.34%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 276px;\"\u003e\n \u003cp\u003ePharmaceutical services help resolve medication confusion and prevent medication errors\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e106(80.92%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e21(16.03%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e4(3.05%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 276px;\"\u003e\n \u003cp\u003ePharmacist supervision and guidance improve my medication adherence (timely, as prescribed), enhancing treatment effectiveness\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e105(80.15%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e19(14.50%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e5(3.82%\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e2(1.53%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 276px;\"\u003e\n \u003cp\u003eI would seek pharmacist help again for future medication issues\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e110(83.97%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e13(9.92%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e5(3.82%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e3(2.29%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 276px;\"\u003e\n \u003cp\u003eI would recommend pharmacists to others if needed\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e101(77.10%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e18(13.74%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e8(6.11%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e4(3.05%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 276px;\"\u003e\n \u003cp\u003eI am willing to accept pharmaceutical services during hospitalization if offered by pharmacists\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e104(79.39%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e14(10.69%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e10(7.63%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e2(1.53%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e1(0.76%)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd style=\"width: 276px;\"\u003e\n \u003cp\u003eI am willing to pay 30 RMB per visit for pharmacy clinic services (covered by health insurance)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e108(82.44%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e10(7.63%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e5(3.82%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e6(4.58%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd style=\"width: 68px;\"\u003e\n \u003cp\u003e2(1.53%)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n \u003c/table\u003e\n\u003c/div\u003e"}],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":true,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":true,"highlight":"","institution":"","isAcceptedByJournal":false,"isAuthorSuppliedPdf":false,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":false,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"Chronic airway diseases, COPD, asthma, pharmaceutical services, medication adherence","lastPublishedDoi":"10.21203/rs.3.rs-6702396/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-6702396/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003e\u003cstrong\u003eBackground\u003c/strong\u003e Chronic airway diseases (CADs) impose substantial health burdens due to poor medication adherence, inhaler misuse, and insufficient disease knowledge, which compromise disease control. Understanding patients' pharmaceutical care needs is critical to improving chronic respiratory disease management.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eMethod\u003c/strong\u003e A cross-sectional survey was conducted among 131 CADs patients attending a pharmaceutical outpatient clinic at a tertiary hospital in Fujian Province, China, from June to August 2024. Data were collected on patients' care priorities, communication preferences, service satisfaction, and influencing factors.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eResults\u003c/strong\u003e Patients prioritized medication guidance (74.81%), disease knowledge (65.65%), and self-management skills (58.02%). Face-to-face communication (77.86%) and concise information delivery (54.96%) were preferred. Despite high satisfaction (90.08%), 54.20% held misconceptions about medication safety (e.g., accepting occasional dose skipping). Physician referrals drove service utilization (90.08%), with minimal influence from external channels like social media.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eConclusion\u003c/strong\u003e Pharmaceutical services for CADs patients should integrate technical support (e.g., inhaler training), patient education, family engagement, and multidisciplinary collaboration. Optimizing service models, enhancing public awareness, and securing policy support are essential to advancing precision pharmaceutical care.\u003c/p\u003e","manuscriptTitle":"Pharmaceutical care needs of patients with chronic respiratory diseases：results from a cross sectional study","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2025-06-10 11:22:56","doi":"10.21203/rs.3.rs-6702396/v1","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"9aa12cfa-4a02-4392-b945-707b19eb0393","owner":[],"postedDate":"June 10th, 2025","published":true,"recentEditorialEvents":[{"type":"decision","content":"Rejected","date":"2026-05-21T11:16:31+00:00","index":"","fulltext":""}],"rejectedJournal":[],"revision":"","amendment":"","status":"posted","subjectAreas":[],"tags":[],"updatedAt":"2026-05-21T11:25:50+00:00","versionOfRecord":[],"versionCreatedAt":"2025-06-10 11:22:56","video":"","vorDoi":"","vorDoiUrl":"","workflowStages":[]},"version":"v1","identity":"rs-6702396","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-6702396","identity":"rs-6702396","version":["v1"]},"buildId":"8U1c8b4HqxoKbykW_rLl7","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}