Clinical Features of Patients Without Fever Infected by SARS-CoV-2: an Observational Study

Abstract Objective: A large number of patients had infected by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). We aimed to clarify the clinical features of the patients without fever infected by SARS-CoV-2.Methods: This is a retrospective and single-center study. We collected and analyzed the data of demographic, clinical presentation, laboratory tests, radiological results, treatment, and complications. The patients with fever and without fever were compared.Results: 113 patients were enrolled in the study, 36 (31.9%) patients without fever on admission. Among the patients without fever, the mean age was 41 years (IQR, 30-53; Range, 8-82years) and 18 (50%) were male. The median from the onset of illness to the first admission was 3.0 days. None of the patients without fever had complications and received high-flow oxygen therapy or invasive ventilation. As of Feb 22, 2020, 8 patients (22.2%) were discharged, and the remaining patients were still hospitalized. Conclusions: Out of 113 patients with SARS-COV-2 infection, patients without fever accounted for 31.9% in total. The clinical prognosis of patients without fever may be better than those of patients with fever on admission.