An Interesting Case of Sister Mary Joseph's Nodule Revealed by 18F-FDG PET.

Oueriagli SN, Sahel OA, Benameur Y, Doudouh A
Indian journal of nuclear medicine : IJNM : the official journal of the Society of Nuclear Medicine, India · 2025 · doi:10.4103/ijnm.ijnm_34_25 · PMID:41064210 · PMC12503169
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Abstract

The Sister Mary Joseph's nodule is a rare umbilical metastatic lesion, occurring in 1%-3% of abdominopelvic adenocarcinomas. It represents the visible tip of the iceberg, and its presence is associated with a poor prognosis. We report the case of a 61-year-old postmenopausal female patient with rectosigmoid adenocarcinoma. An 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET) scan revealed, in addition to a large sigmoid mass, multiple hypermetabolic lumbo-aortic lymphadenopathies, secondary hypermetabolic pulmonary and hepatic nodules, and a large subcutaneous umbilical nodule consistent with a Sister Marie Joseph's nodule. This case supports the systematic use of 18F-FDG PET in oncologic evaluations involving suspicious umbilical nodules.
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Authorship

S. O. N. Design: S. O. N., O. A. S., Y. B., A. D., Data Collection or Processing: S. N. O., Analysis or Interpretation: S. N. O, A. D., Literature Search: S. N. O, O. A. S, Writing: S. N. O.

Declaration

The authors certify that they have obtained all appropriate patient consent forms. In the form, the patient has given her consent for her images and other clinical information to be reported in the journal. The patient understands that her name and initials will not be published and due efforts will be made to conceal identity, but anonymity cannot be guaranteed.

Coi Statement

There are no conflicts of interest.

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