Endometriosis Should Be Suppressed for 6–12 Weeks before Frozen Embryo Transfer
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Abstract
Endometriosis-associated infertility is a common indication for in vitro fertilisation (IVF) treatment. There is great controversy regarding the outcome of IVF in such patients. Possibly inferior results compared with other indications for IVF are likely based on reduced oocyte and embryo quality and not adverse endometrial receptivity. Such knowledge is based on IVF crossover studies with donor oocytes and patient’s own oocytes to women with and without endometriosis. Embryos that are frozen and later thawed for transfer to the uterus are selected among the best embryos in a fresh cycle. Transfer of such embryos is as successful in endometriosis as in other causes of infertility whatever endometrial preparation is used. Thus, long-term suppression of endometriosis with GnRH agonists in frozen embryo transfer is unnecessary and may possibly be harmful due to induction of endometritis.
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References (7)
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- Long-term GnRH agonist therapy before in vitro fertilisation (IVF) for improving fertility outcomes in women with endometriosis via openalex
- W2165754964 via openalex
- W6684429272 via openalex
- W6757729189 via openalex
- W2903585683 via openalex
- W2318998837 via openalex
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