Accumulated reserves hold back age-related neural compensation in speech-in-noise perception

Accumulated reserves hold back age-related neural compensation in speech-in-noise perception | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Article Accumulated reserves hold back age-related neural compensation in speech-in-noise perception Claude Alain, Lei Zhang, Bernhard Ross, Yi Du This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-4559256/v1 This work is licensed under a CC BY 4.0 License Status: Under Review Version 1 posted You are reading this latest preprint version Abstract Recruitment of neural activity or functional connectivity is commonly observed in older adults but poorly understood. We measured brain activity with fMRI during speech-in-noise tasks and assessed whether accumulated reserve accrued through musical training bolsters or holds back age-related neural compensation. Older musicians exhibited less upregulation of task-induced functional connectivity than older non-musicians in dorsal regions, which predicted better behavioral performance in older musicians. The findings suggest that accumulated reserve may hold back neural recruitment. Besides functional connectivity strength, we also found that older musicians showed more youth-like fine spatial patterns of functional connectivity than older non-musicians. However, benefits from visual lip movements were not specific to either hypothesis. Aligning with enhanced benefits in behavioral performance, older musicians showed more extensive functional connectivity enhancement, specifically in the right hemisphere, than older non-musicians. Our findings enlightened the intricate interplay between accumulated reserve and age-related neural compensation during speech in noise perception. Biological sciences/Psychology/Human behaviour Biological sciences/Neuroscience/Cognitive ageing Biological sciences/Neuroscience/Cognitive neuroscience/Perception Biological sciences/Neuroscience/Sensory processing Full Text Additional Declarations There is NO Competing Interest. Supplementary Files Supplementarymaterial.docx Accumulated reserves hold back age-related neural compensation in speech-in-noise perception Cite Share Download PDF Status: Under Review Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. 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Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-4559256","acceptedTermsAndConditions":true,"allowDirectSubmit":false,"archivedVersions":[],"articleType":"Article","associatedPublications":[],"authors":[{"id":316430880,"identity":"cf9efc3c-16e5-4be3-b049-dd33b3e92a4c","order_by":0,"name":"Claude 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