Response: Clues to revising the conventional diagnostic algorithm for endometriosis

other OA: closed public-domain-us
Full text JSON View on PubMed View at publisher
AI-generated summary by claude@2026-06, 2026-06-08

This paper offers insights that could lead to improvements in the standard diagnostic process for endometriosis, based on the authors' findings.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

Full text 8,901 characters · extracted from oa-doi-fallback · click to expand
Response: Clues to revising the conventional diagnostic algorithm for endometriosis Corresponding Author Andrew Spiers Department of Obstetrics and Reproductive Medicine, Angers University Hospital, Angers, France Endometriosis Expert Center – Pays de la Loire, Angers, France Correspondence Andrew Spiers, Department of Gynecology-Obstetrics, Angers University, Hospital, 4 Rue Larrey, 49100 Angers, France. Email: [email protected] Search for more papers by this authorHorace Roman Franco-European Multidisciplinary Endometriosis Institute (IFEMEndo), Clinique Tivoli-Ducos, Bordeaux, France Search for more papers by this authorMegan Wasson Department of Gynecologic Surgery, Mayo Clinic, Phoenix, Arizona, USA Search for more papers by this authorCharles Chapron Department of Gynecology Obstetrics and Reproductive Medicine, Cochin University Hospital, Paris, France Department ‘Development, Reproduction and Cancer’, Institut Cochin, INSERM U1016, Descartes University, Paris, France Search for more papers by this authorPascal Rousset Department of Diagnostic and Interventional Imaging, Lyon Sud University Hospital, Lyon, France Search for more papers by this authorFrançois Golfier Department of Obstetrics and Reproductive Medicine, Lyon South University Hospital, Lyon, France Endometriosis Expert Center—Steering Committee of the EndAURA Network, Lyon, France Search for more papers by this authorRaffaele Fauvet Department of Obstetrics and Reproductive Medicine, Cote De Nacre University Hospital, Caen, France Search for more papers by this authorLéa Delbos Department of Obstetrics and Reproductive Medicine, Angers University Hospital, Angers, France Endometriosis Expert Center – Pays de la Loire, Angers, France Search for more papers by this authorHervé Fernandez Department of Obstetrics and Reproductive Medicine, Paris Sud University Hospital, Kremlin Bicetre APHP, Paris, France Search for more papers by this authorPhilippe Descamps Department of Obstetrics and Reproductive Medicine, Angers University Hospital, Angers, France Endometriosis Expert Center – Pays de la Loire, Angers, France Search for more papers by this authorSofiane Bendifallah Department of Surgery, American Hospital of Paris, Neuilly sur seine, France Search for more papers by this authorCorresponding Author Andrew Spiers Department of Obstetrics and Reproductive Medicine, Angers University Hospital, Angers, France Endometriosis Expert Center – Pays de la Loire, Angers, France Correspondence Andrew Spiers, Department of Gynecology-Obstetrics, Angers University, Hospital, 4 Rue Larrey, 49100 Angers, France. Email: [email protected] Search for more papers by this authorHorace Roman Franco-European Multidisciplinary Endometriosis Institute (IFEMEndo), Clinique Tivoli-Ducos, Bordeaux, France Search for more papers by this authorMegan Wasson Department of Gynecologic Surgery, Mayo Clinic, Phoenix, Arizona, USA Search for more papers by this authorCharles Chapron Department of Gynecology Obstetrics and Reproductive Medicine, Cochin University Hospital, Paris, France Department ‘Development, Reproduction and Cancer’, Institut Cochin, INSERM U1016, Descartes University, Paris, France Search for more papers by this authorPascal Rousset Department of Diagnostic and Interventional Imaging, Lyon Sud University Hospital, Lyon, France Search for more papers by this authorFrançois Golfier Department of Obstetrics and Reproductive Medicine, Lyon South University Hospital, Lyon, France Endometriosis Expert Center—Steering Committee of the EndAURA Network, Lyon, France Search for more papers by this authorRaffaele Fauvet Department of Obstetrics and Reproductive Medicine, Cote De Nacre University Hospital, Caen, France Search for more papers by this authorLéa Delbos Department of Obstetrics and Reproductive Medicine, Angers University Hospital, Angers, France Endometriosis Expert Center – Pays de la Loire, Angers, France Search for more papers by this authorHervé Fernandez Department of Obstetrics and Reproductive Medicine, Paris Sud University Hospital, Kremlin Bicetre APHP, Paris, France Search for more papers by this authorPhilippe Descamps Department of Obstetrics and Reproductive Medicine, Angers University Hospital, Angers, France Endometriosis Expert Center – Pays de la Loire, Angers, France Search for more papers by this authorSofiane Bendifallah Department of Surgery, American Hospital of Paris, Neuilly sur seine, France Search for more papers by this authorDATA AVAILABILITY STATEMENT Data sharing is not applicable to this article as no new data were created or analyzed in this study. REFERENCES - 1Spiers A, Roman H, Wasson M, et al. Clues to revising the conventional diagnostic algorithm for endometriosis. Int J Gynaecol Obstet. 2025; 168(1): 101-111. doi:10.1002/ijgo.15840 - 2Bendifallah S, Puchar A, Suisse S, et al. Machine learning algorithms as new screening approach for patients with endometriosis. Sci Rep. 2022; 12: 639. doi:10.1038/s41598-021-04637-2 - 3Chapron C, Lafay-Pillet M-C, Santulli P, et al. A new validated screening method for endometriosis diagnosis based on patient questionnaires. EClinicalMedicine. 2022; 44:101263. doi:10.1016/j.eclinm.2021.101263 - 4Becker CM, Bokor A, Heikinheimo O, et al. ESHRE guideline: endometriosis. Human Reproduction Open. 2022; 2:hoac009. doi:10.1093/hropen/hoac009 10.1093/hropen/hoac009Google Scholar - 5Howard FM. An evidence-based medicine approach to the treatment of endometriosis-associated chronic pelvic pain: placebo-controlled studies. J Am Assoc Gynecol Laparosc. 2000; 7(4): 477-488. doi:10.1016/s1074-3804(05)60360-x - 6Guo S-W. Recurrence of endometriosis and its control. Hum Reprod Update. 2009; 15(4): 441-461. doi:10.1093/humupd/dmp007 - 7Brown J, Crawford TJ, Allen C, Hopewell S, Prentice A, Cochrane Gynaecology and Fertility Group. Nonsteroidal anti-inflammatory drugs for pain in women with endometriosis. Cochrane Database Syst Rev. 2017; 1(1):CD004753. doi:10.1002/14651858.CD004753.pub4 - 8Chapron C, Marcellin L, Borghese B, Santulli P. Rethinking mechanisms, diagnosis and management of endometriosis. Nat Rev Endocrinol. 2019; 15(11): 666-682. doi:10.1038/s41574-019-0245-z - 9Bendifallah S, Dabi Y, Suisse S, et al. Validation of a salivary miRNA signature of endometriosis – interim data. NEJM Evidence. 2023; 2,7:EVIDoa2200282. doi:10.1056/EVIDoa2200282 10.1056/EVIDoa2200282Google Scholar - 10Ferrier C, Bendifallah S, Suisse S, et al. Saliva microRNA signature to diagnose endometriosis: a cost-effectiveness evaluation of the Endotest®. BJOG. 2023; 130(4): 396-406. doi:10.1111/1471-0528.17348 - 11Bendifallah S, Roman H, Suisse S, et al. Validation of a saliva micro-RNA signature for endometriosis. NEJM Evidence. 2025; 4:EVIDoa2400195. doi:10.1056/EVIDoa2400195 - 12 ClinicalTrials.gov [Internet]. Interest of Salivary Signature of Endometriosis in the Healthcare Pathway of Adolescent: The ADOmiARN Study. Bethesda, MD: National Library of Medicine (US). Identifier NCT05928442, July 3, 2023. Accessed April 26, 2026. https://clinicaltrials.gov/study/NCT05928442 - 13 ClinicalTrials.gov [Internet]. Impact of Ziwig Endotest® on the Management of Patients With Clinical Symptoms of Endometriosis Inconsistent With Their Imaging Work-up: ENDOBEST. Bethesda, MD: National Library of Medicine (US). Identifier NCT06794424. Accessed April 26, 2026. https://clinicaltrials.gov/study/NCT06794424 Article Metrics Total unique accesses to an article’s full text in HTML or PDF/ePDF format.More metric information Scite metrics Explore this article's citation statements on scite.ai Share QR Code Generating QR code QR code copied to clipboard! Something went wrong while generating your QR code. Please try again in a moment. If the issue persists, refresh the page or contact support. Export citation Unable to load citation data. Please try again in a moment. How to cite Elkins, L. J., & Spiegelman, M. (2021). pyUserCalc: A revised Jupyter notebook calculator for uranium-series disequilibria in basalts. Earth and Space Science, 8, e2020EA001619. https://doi.org/10.1029/2020EA001619 Download Citation If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your manager software from the list below and click on download. This feature enables you to download the bibliographic information (also called citation data, header data, or metadata) for the articles on our site. Citation manager file format Use the dropdown list to choose how to format the bibliographic data you're harvesting. Several citation manager formats are available, including EndNote and BibTex. You can then copy the formatted citation (as displayed) or download it as file, to your device. If the RefWorks format is chosen, the 'Download' button will be replaced with an option to directly export to RefWorks

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

Ask this paper AI returns verbatim quotes from the full text · source: oa-doi-fallback

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Condition tags

endometriosis

Citation neighborhood (no data yet)

We don't have any in-corpus citations linked to this paper yet. This is a recent paper (2026) — citers typically take a year or two to land, and the OpenAlex reference graph may still be filling in.

Source provenance

europepmc
last seen: 2026-06-04T01:30:01.192114+00:00
pubmed
last seen: 2026-05-31T00:30:09.580481+00:00
unpaywall
last seen: 2026-05-11T08:34:28.763810+00:00
License: public-domain-us · commercial use OK · attribution required
Courtesy of the U.S. National Library of Medicine