Correlation, clinicopathological and imaging analysis of radial scar and breast cancer

Background: To analyze the imaging and clinicopathological manifestations of radial scars, and to evaluate the pathological escalation rate. Methods A retrospective analysis of 63 cases of breast biopsy with radioactive scar in the Breast Surgery Department of Xiamen Maternal and Child Health Hospital from January 1, 2011 to January 1, 2016, 34 patients underwent further surgical resection after puncture; 29 patients did not undergo surgery after puncture, and these patients were followed up. Radiographic, clinical, and pathological findings were statistically analyzed and escalation rates were calculated. Results Of the 63 RS cases, 34 (54%) underwent routine surgical resection. In the surgical resection group, 2 (5.9%) cases were pathologically upgraded to malignant after operation. Twenty-nine (46%) cases underwent follow-up observation, and 1 (3.4%) case was upgraded to malignant. Compared with the observation group, the age of onset, menopausal status, smoking, family history of breast cancer, symptoms, ultrasound lesion diameter, ultrasound and mammography BI-RADS grade were not statistically significant between the surgical resection group and the observation group (all P  > 0.05). The incidence of high-risk lesions of radial scar in the surgical resection group was significantly higher than that in the observation group ( P  = 0.02). Conclusions The escalation rate of malignant lesions in RS is low, and surgical resection is recommended when needle biopsy is associated with high-risk breast lesions.