Effectiveness of Prone Positioning on Oxygenation in Ventilated Neonates – A Randomised Control Trial

Effectiveness of Prone Positioning on Oxygenation in Ventilated Neonates – A Randomised Control Trial | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Article Effectiveness of Prone Positioning on Oxygenation in Ventilated Neonates – A Randomised Control Trial Abhijit Diwate, Subhash Khatri, Abhijit Shinde, Siddharth jain, and 2 more This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-5948449/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract Background : Proper positioning and the integration of chest physiotherapy (CPT) have emerged as beneficial supportive strategies in respiratory management of ventilated newborns. This study was designed to evaluate the effect of CPT and prone positioning on short term oxygen requirement in ventilated newborns. Methods : Eighty ventilated neonates fitting in inclusion criteria were randomly divided into the Experimental group (CPT and Prone Positioning) and the Control group (CPT). Seventy-four completed the study protocol (i.e.37 in each group). Outcomes were Arterial Oxygen Saturation (SpO2), Partial Pressure of Arterial Oxygen (PaO2), and Fraction of Inspired Oxygen (FiO2). Outcomes were recorded twice daily for 3 days. Result : Oxygenation was found to be significantly higher in the subjects who received prone positioning along with CPT when compared with subjects who were treated with CPT alone. Conclusion : CPT is useful adjunct therapy to prone positioning for mechanically ventilated newborns. Health sciences/Medical research/Outcomes research Health sciences/Medical research/Translational research Chest Physiotherapy Positioning Ventilated neonates Prone Full Text Additional Declarations There is NO conflict of interest to disclose. Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-5948449","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Article","associatedPublications":[],"authors":[{"id":453279052,"identity":"b54f0109-c90d-4b57-8826-148c99c0ae5b","order_by":0,"name":"Abhijit Diwate","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAA9ElEQVRIiWNgGAWjYDACCR6GAxIGDIxtYF4FEDMzNxCjxQCkhbGB4QxICyNhLUBgAFLG2ACxi4AW/tm9Bw9YFPyR7ZNIfv7g47zaaP52oJYfFdtwW3LnXALIYcZtEmmGjTO3Hc+dcRhoW8+Z27ituZFjANKS2CadYNjMu+1YbgNQCzNjG24t8ggt6R+b/845ljufkBYDhJYcw2bGhprcDYS0GN45A9JibNwm/6ZwZs+xA7kbgVoO4vOL3O0e488Sf+Rk5/cc3/DhR01d7rzzhw8++FGBx/tAwCyBYB8GkwfwqgcCxg8Idh0hxaNgFIyCUTACAQDWpGFzDBwmSQAAAABJRU5ErkJggg==","orcid":"","institution":"Dr. Vithalrao Vikhe Patil Foundation’s College of Physiotherapy","correspondingAuthor":true,"prefix":"","firstName":"Abhijit","middleName":"","lastName":"Diwate","suffix":""},{"id":453279053,"identity":"7cd991cb-1e19-4889-aafd-47bfa12a401f","order_by":1,"name":"Subhash Khatri","email":"","orcid":"","institution":"Sankalchand Patel University","correspondingAuthor":false,"prefix":"","firstName":"Subhash","middleName":"","lastName":"Khatri","suffix":""},{"id":453279054,"identity":"7703b008-4775-42a9-80c4-5d75e37982d9","order_by":2,"name":"Abhijit Shinde","email":"","orcid":"https://orcid.org/0000-0001-6142-8260","institution":"Dr. Vithalrao Vikhe Patil Foundation's College of Physiotherapy","correspondingAuthor":false,"prefix":"","firstName":"Abhijit","middleName":"","lastName":"Shinde","suffix":""},{"id":453279055,"identity":"f316f959-afec-42f0-83d7-186187c360fe","order_by":3,"name":"Siddharth jain","email":"","orcid":"","institution":"Corewell Health Dearborn hospital","correspondingAuthor":false,"prefix":"","firstName":"Siddharth","middleName":"","lastName":"jain","suffix":""},{"id":453279056,"identity":"04de08bd-de72-4e39-be91-b79cdc820a2d","order_by":4,"name":"Abhijit D. 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This study was designed to evaluate the effect of CPT and prone positioning on short term oxygen requirement in ventilated newborns.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eMethods\u003c/strong\u003e: Eighty ventilated neonates fitting in inclusion criteria were randomly divided into the Experimental group (CPT and Prone Positioning) and the Control group (CPT). Seventy-four completed the study protocol (i.e.37 in each group). Outcomes were Arterial Oxygen Saturation (SpO2), Partial Pressure of Arterial Oxygen (PaO2), and Fraction of Inspired Oxygen (FiO2). Outcomes were recorded twice daily for 3 days.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eResult\u003c/strong\u003e: Oxygenation was found to be significantly higher in the subjects who received prone positioning along with CPT when compared with subjects who were treated with CPT alone.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eConclusion\u003c/strong\u003e: CPT is useful adjunct therapy to prone positioning for mechanically ventilated newborns.\u003c/p\u003e","manuscriptTitle":"Effectiveness of Prone Positioning on Oxygenation in Ventilated Neonates – A Randomised Control Trial","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2025-05-12 12:49:23","doi":"10.21203/rs.3.rs-5948449/v1","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"87d7e941-54a6-4a66-ac53-a99c3d4460e5","owner":[],"postedDate":"May 12th, 2025","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"posted","subjectAreas":[{"id":48402244,"name":"Health sciences/Medical research/Outcomes research"},{"id":48402245,"name":"Health sciences/Medical research/Translational research"}],"tags":[],"updatedAt":"2025-07-31T13:40:28+00:00","versionOfRecord":[],"versionCreatedAt":"2025-05-12 12:49:23","video":"","vorDoi":"","vorDoiUrl":"","workflowStages":[]},"version":"v1","identity":"rs-5948449","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-5948449","identity":"rs-5948449","version":["v1"]},"buildId":"8U1c8b4HqxoKbykW_rLl7","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}