Exacerbation of endometriosis due to regulatory T cell dysfunction

佑輝子 田中
· W7146124553
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This study investigated how regulatory T cell dysfunction exacerbates endometriosis, observing this phenomenon in the context of the WEKO3 research context.

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This thesis investigates the role of regulatory T cells in the progression of endometriosis, specifically examining how their dysfunction contributes to disease exacerbation. The research utilizes a mouse model of endometriosis to analyze immune responses and lesion growth under conditions of impaired regulatory T cell activity. Key findings indicate that compromised regulatory T cell function leads to increased inflammation and more severe endometriotic lesions compared to controls with intact immune regulation. This paper is centrally about endometriosis — specifically the immunological mechanisms involving regulatory T cell dysfunction that drive lesion severity.

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WEKO3 アイテム Exacerbation of endometriosis due to regulatory T cell dysfunction https://kpu-m.repo.nii.ac.jp/records/2172 https://kpu-m.repo.nii.ac.jp/records/2172dc7fc564-fbc4-4c6d-94df-f7814aea41c4 | 名前 / ファイル | ライセンス | アクション | |---|---|---| | 論文要旨 (76.6 kB) | | | | 審査要旨 (151.9 kB) | | | アイテムタイプ | 学位論文 / Thesis or Dissertation(1) | ||||||||| |---|---|---|---|---|---|---|---|---|---|---| | 公開日 | 2018-08-08 | ||||||||| | タイトル | |||||||||| | タイトル | Exacerbation of endometriosis due to regulatory T cell dysfunction | ||||||||| | 言語 | en | ||||||||| | 言語 | |||||||||| | 言語 | eng | ||||||||| | 資源タイプ | |||||||||| | 資源タイプ | thesis | ||||||||| | その他（別言語等）のタイトル | |||||||||| | ja | |||||||||| | 制御性Ｔ細胞の機能不全が子宮内膜症を悪化させる | |||||||||| | 著者 | 田中, 佑輝子 × 田中, 佑輝子 | ||||||||| | 学位名 | |||||||||| | 学位名 | 博士（医学） | ||||||||| | 学位授与機関 | |||||||||| | 学位授与機関名 | 京都府立医科大学 | ||||||||| | 学位授与年度 | |||||||||| | 内容記述タイプ | Other | ||||||||| | 内容記述 | 平成29年度 | ||||||||| | 学位授与年月日 | |||||||||| | 学位授与年月日 | 2017-12-14 | ||||||||| | 学位授与番号 | |||||||||| | 学位授与番号 | 甲第1681号 | ||||||||| | 関連サイト | |||||||||| | 識別子タイプ | DOI | ||||||||| | 関連識別子 | https://doi.org/10.1210/jc.2017-00052 | ||||||||| | 関連名称 | リンク | ||||||||| | 研究科目 | |||||||||| | 主題Scheme | Other | ||||||||| | 主題 | 女性生涯医科学 |

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