The Prevalence of Helicobacter Pylori Infection and the Associated Demographic and Histopathological Characteristics as seen in Patients Diagnosed with Chronic Gastritis in Uganda.

The Prevalence of Helicobacter Pylori Infection and the Associated Demographic and Histopathological Characteristics as seen in Patients Diagnosed with Chronic Gastritis in Uganda. | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article The Prevalence of Helicobacter Pylori Infection and the Associated Demographic and Histopathological Characteristics as seen in Patients Diagnosed with Chronic Gastritis in Uganda. Okello Malcom Mark, Musoke Sharrif, Omega Phillip, Asiimwe Ivan, and 7 more This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-7371222/v1 This work is licensed under a CC BY 4.0 License Status: Under Review Version 1 posted 15 You are reading this latest preprint version Abstract Background: Chronic gastritis is marked by persistent stomach mucosal inflammation due to a variety of etiologies but more commonly driven by Helicobacter pylori ( H. pylori ) infection, affecting over half the global population and increasing gastric cancer risk. This study investigated H. pylori prevalence, its demographic and histopathological associations among chronic gastritis patients in Uganda. Methods: A cross-sectional laboratory study analyzed 150 formalin-fixed paraffin-embedded tissue blocks from chronic gastritis patients using H&E and modified Giemsa stains. Data was analyzed with STATA version 17, determining prevalence through proportions, assessing associations using Chi-square tests and Fisher exact test, and conducting multivariate analysis with logistic regression. Significance was set at p≤0.05 with 95% confidence intervals. Results: The study included 150 patients (male-to-female ratio 1.5:1; mean age 48 years, SD=17, range 12–89). H. pylori prevalence was 29.3%. Significant associations were observed with age (p=0.033), chronic inflammation (p=0.009), neutrophil activity (p<0.001), and intestinal metaplasia (p=0.045), but not sex (p=0.796). Multivariate analysis confirmed associations with severe chronic inflammation, neutrophil activity, and intestinal metaplasia, highlighting H. pylori ’s role in disease severity. Conclusion: H. pylori infection, with a 29.3% prevalence, significantly contributes to chronic gastritis in Uganda. Its associations with age, chronic inflammation, neutrophil activity, and intestinal metaplasia emphasize the need for targeted eradication programs, particularly for adults, to prevent progression to severe gastric pathology, regardless of sex. Helicobacter pylori chronic gastritis prevalence histopathology Uganda 1. Background Chronic gastritis is a persistent inflammatory condition of the gastric mucosa, primarily characterized by infiltration of lymphocytes, plasma cells, and, less commonly, granulocytes (1). This histopathological profile leads to a wide range of clinical outcomes, from mild abdominal discomfort to severe complications such as peptic ulcers, gastric atrophy, intestinal metaplasia, gastric adenocarcinoma, and mucosa-associated lymphoid tissue (MALT) lymphoma(2-4). Affecting over half of the global population, chronic gastritis represents a major public health burden, particularly in regions with limited healthcare infrastructure (5). The leading cause of chronic gastritis is Helicobacter pylori ( H. pylori ), a Gram-negative, spiral-shaped, motile bacterium uniquely adapted to thrive in the stomach’s acidic, microaerophilic environment (6). Through mechanisms such as urease enzyme secretion, which neutralizes gastric acid, and multiple flagella that enable motility, H. pylori effectively colonizes the gastric mucosa (7). Its prevalence is alarmingly high in developing countries, where inadequate sanitation and healthcare access facilitate its spread (3). In Africa, infection rates often exceed 70%, driven by early childhood acquisition, including mother-to-child transmission (8, 9). Socioeconomic challenges, such as poor hygiene and limited healthcare resources, further exacerbate infection rates in low-income regions compared to developed nations (10, 11). In Uganda, high rates of H. pylori infection have been documented, with studies reporting positive stool antigen tests among patients in Kampala, yet detailed insights into associated demographic and histopathological characteristics remain scarce (12). Chronic gastritis driven by H. pylori significantly increases the risk of severe gastrointestinal complications. Approximately 10% of affected individuals develop peptic ulcer disease, while 1–3% progress to gastric cancers, including adenocarcinoma, due to the bacterium’s carcinogenic properties . Classified as a Group 1 carcinogen by the International Agency for Research on Cancer (IARC), H. pylori is a key contributor to gastric cancer development (6, 13). The global rise in antibiotic resistance further complicates treatment, amplifying morbidity and mortality (14). In resource-constrained settings like Uganda, where H. pylori prevalence is high, understanding its epidemiology and histopathological impact is essential for designing effective prevention and treatment strategies. This study aimed to determine the prevalence of H. pylori infection and characterize its associated demographic and histopathological features among patients diagnosed with chronic gastritis in Uganda. 2. Methods 2.1 Study Design and Setting This study was a cross-sectional, laboratory-based investigation with a retrospective approach, aimed at determining the prevalence of Helicobacter pylori ( H. pylori ) infection and characterizing its associated demographic and histopathological features in patients diagnosed with chronic gastritis in Uganda. The study was conducted at the pathology departments of Mulago National Referral Hospital (MNRH), Makerere University, and the Uganda Cancer Institute (UCI) in Kampala, Uganda’s capital city. These national reference centers provide diagnostic cytology, histopathology, and autopsy services, processing approximately 20,000 tissue biopsies annually, including around 50 formalin-fixed paraffin-embedded (FFPE) blocks diagnosed with chronic gastritis per year. 2.2 Study Population The study population comprised FFPE tissue blocks from patients with a histologically confirmed diagnosis of chronic gastritis, archived at the pathology departments of MNRH, Makerere University, and UCI between September 2018 and August 2021. A total of 150 blocks were included, representing patients aged 5 years and older, with request forms documenting age and sex. Inclusion Criteria FFPE tissue blocks with histologically confirmed chronic gastritis and accompanying request forms specifying age and sex. Blocks from patients aged 5 years and older. Exclusion Criteria Blocks with inadequate or depleted tissue. Blocks diagnosed with gastric carcinoma or mucosa-associated lymphoid tissue (MALT) lymphoma. Extensively damaged blocks. Blocks with incomplete patient information (e.g., missing age or sex). Blocks with extensive necrosis. 2.3 Sample Size Calculation The sample size was calculated using the Kish-Leslie formula (Kish, 1965): Where: N = Sample size Z= Standard normal deviation at a 95% confidence interval, corresponding to 1.96 P = Estimated proportion of H. pylori infection in chronic gastritis cases (set at 0.5 due to unknown prevalence in Uganda) E = Margin of error accepted in this study, set at 5% (0.05). Due to the limited availability of 150 eligible FFPE blocks, all were analyzed. While this sample size is below the calculated 384, it was deemed sufficient for exploratory analysis given the constrained population. 2.4 Sample Collection and Processing 2.4.1 Sample Collection FFPE tissue blocks were retrieved from the archives of MNRH, Makerere University, and UCI pathology departments. Blocks were selected based on a histological diagnosis of chronic gastritis from September 2018 to August 2021. Each block was uniquely labeled to ensure accurate identification. 2.4.2 Sample Processing Two 4-micrometer sections were cut from each FFPE block using standard histological techniques ( Supplement 1 ). One section was stained with hematoxylin and eosin (H&E) to confirm the chronic gastritis diagnosis ( Supplement 2 ). The second section was stained with modified Giemsa to detect H. pylori , identified by its purple or pink spiral/curved morphology against a blue background ( Supplement 3 ). Staining was performed by the principal investigator (PI) with assistance from a qualified laboratory technician, following standardized protocols. 2.4.3 Histopathological Evaluation H&E-Stained Slides were examined using light microscope grading; chronic inflammation, neutrophil activity, glandular atrophy, and intestinal metaplasia using the Modified Sydney System (1) on a scale of 0 (none) to 3 (severe) (S4). Intestinal metaplasia was identified by goblet and absorptive cells, and H. pylori density was quantified based on bacterial presence on the surface epithelium. Supervising pathologists confirmed the findings. Modified Giemsa-Stained Slides: The PI evaluated slides under oil immersion (100x magnification) for H. pylori . Supervising pathologists verified results. Digital images were captured using a Nikon Eclipse Ci-L multi-header microscope for documentation. 2.5 Data Collection Data were collected using paper-based forms ( Supplement 5 ), with each block assigned a unique case number to ensure confidentiality. Patient names and biopsy numbers were excluded. The PI recorded histopathological findings ( H. pylori presence, density, and characteristics such as chronic inflammation, neutrophil activity, glandular atrophy, and intestinal metaplasia) and demographic data (age, sex). Supervising pathologists independently reviewed the slides, and discrepancies were resolved via collaborative review on a multi-header microscope. 2.6 Statistical Analysis Data were entered into Microsoft Excel, cleaned, and transferred to Stata version 17.0 (StataCorp) for analysis. Normality was assessed using the Shapiro-Wilk test. A qualified biostatistician conducted the analysis. The prevalence of H. pylori infection was calculated as a proportion. Continuous variables (e.g., H. pylori density) were summarized as means with standard deviations (SD). Categorical variables (e.g., chronic inflammation severity, neutrophil activity, glandular atrophy, intestinal metaplasia, sex, age, and H. pylori presence) were reported as frequencies and percentages in tables. Chi-square tests with p-values evaluated associations between H. pylori infection and independent variables (demographic and histopathological characteristics). Bivariate logistic regression calculated crude odds ratios (ORs). Multivariate logistic regression included all variables to compute adjusted ORs and assess confounding, defined as a >10% change between crude and adjusted ORs for significant variables. Statistical significance was set at a 95% confidence interval and p ≤ 0.05. Results were presented using descriptive text and tables. 2.7 Quality Control Standard operating procedures were adhered to throughout the study. Slides were carefully mounted to prevent detachment or artifacts. H&E and modified Giemsa staining followed standardized protocols ( Supplement 2 and Supplement 3 ), with positive and negative controls (known H. pylori -positive and -negative cases) included in each batch to ensure accuracy. Staining quality was assessed for clarity, uniformity, and absence of artifacts. Issues prompted repeat staining with fresh reagents. The PI and two supervising pathologists, blinded to age and sex, independently reviewed slides to minimize bias. Discrepancies were resolved collaboratively. Data analysis was supported by an experienced biostatistician to ensure accuracy. 3. Results 3.1 Demographic and Histopathological Characteristics of Patients A total of 150 formalin-fixed paraffin-embedded (FFPE) tissue specimens from patients diagnosed with chronic gastritis were analyzed. The patients ranged in age from 12 to 89 years, with a mean age of 48 years (standard deviation [SD] = 17 years) and a median age of 47 years (interquartile range [IQR] = 38–58 years). Males comprised 60% (n=90) of the study population, while females accounted for 40% (n=60), as shown in Table 1 . Histopathological characteristics, assessed using the Modified Sydney System, included chronic inflammation, neutrophil activity, glandular atrophy, intestinal metaplasia, and dysplasia. Chronic inflammation was predominantly moderate (55.3%, n=83), while neutrophil activity was mild in 25.3% (n=38) of cases, with 40.0% (n=60) showing no activity. Glandular atrophy was absent in 67.3% (n=101) of cases, and intestinal metaplasia was absent in 92.7% (n=139). H. pylori infection density was moderate in 17.3% (n=26) of cases, with 70.7% (n=106) showing no infection. Dysplasia, observed in a subset of cases, was mild in most instances. These findings are summarized in Table 2 . Representative photomicrographs of histopathological findings are presented as Plate 1 , Plate 2 , Plate 3 , Plate 4 , Plate 5 , Plate 6 and Plate 7 : 3.2 Prevalence and Density of H. pylori Infection Of the 150 patients, 44 (29.3%) tested positive for H. pylori infection, yielding a prevalence of 29.3%. Among those with H. pylori infection, the density was mild in 8.7% (n=13), moderate in 17.3% (n=26), and severe in 3.3% (n=5). 3.3 Association Between H. pylori Infection Density and Histopathological Features A strong correlation was observed between H. pylori infection density and histopathological characteristics, including chronic inflammation (p<0.001), neutrophil activity (p<0.001), glandular atrophy (p=0.009), and intestinal metaplasia (p<0.001). These associations, assessed using Chi-square tests, are detailed in Table 3 . 3.4 Association Between H. pylori Infection and Age A statistically significant association was found between H. pylori infection and age groups (p=0.032). The infection was most prevalent in the 19–59 years age group (34.8%, n=39), compared to 15.2% (n=5) in those ≥60 years and 0% (n=0) in the 5–18 years group as shown in Table 4 . 3.5 Association Between H. pylori Infection and Sex No statistically significant association was observed between H. pylori infection and sex (p=0.796). Infection rates were slightly higher in males (30.0%, n=27) than in females (26.7%, n=16), but the difference was not significant as shown in Table 5 . 3.6 Factors Associated with H. pylori Infection 3.6.1 Bivariate Analysis Bivariate logistic regression revealed significant associations between Helicobacter pylori infection and several factors. Compared to the 19–59 years age group, patients aged 60 years and older had lower odds of infection (crude odds ratio [OR]=0.33, p=0.033). The odds of infection were slightly lower in females compared to males (crude OR=0.85, p=0.658), but this difference was not statistically significant. The odds of H. pylori infection increased significantly with moderate chronic inflammation (crude OR=9.8, p=0.030) and severe chronic inflammation (crude OR=494, p<0.001) compared to mild inflammation, mild to severe neutrophil activity (crude OR=25.4, p<0.001) compared to no activity, mild to severe glandular atrophy (crude OR=4.5, p<0.001) compared to no atrophy, and mild intestinal metaplasia (crude OR=13.4, p=0.001) compared to no metaplasia, as summarized in Table 6 . 3.6.2 Multivariate Logistic Regression Analysis Multivariate logistic regression, adjusting for all variables, identified independent factors associated with Helicobacter pylori infection, as summarized in Table 7 . The adjusted odds ratios (AORs) were 215 (95% confidence interval [CI]: 14.45–3221.87, p<0.001) for severe chronic inflammation compared to mild inflammation, 12.6 (95% CI: 1.87–84.35, p=0.009) for mild to severe neutrophil activity compared to no activity, and 11.6 (95% CI: 1.05–126.69, p=0.045) for mild intestinal metaplasia compared to no metaplasia. Age, sex, and glandular atrophy were not significantly associated with H. pylori infection in the multivariate model. 4. Discussion This study examined the prevalence of Helicobacter pylori (H. pylori) infection and its associated demographic and histopathological characteristics among 150 patients with chronic gastritis in Uganda, offering valuable insights into its epidemiology in a resource-limited setting. The findings revealed a prevalence of 29.3% for H. pylori infection, with generally mild bacterial density, aligning closely with global estimates, such as 34.7% reported in a prior study (15), but exceeding the 16.8% observed in Italy (16). However, this prevalence is notably lower than the 40–70% reported in other African regions (15, 17, 18). A global analysis across 111 countries documented a 15.9% decline in H. pylori prevalence over recent decades, particularly in adults in Africa (19) Several factors may explain this lower prevalence in Uganda. Enhanced public health measures, including improved sanitation, access to clean water, and better hygiene practices, likely reduced H. pylori transmission, especially in urbanizing areas. Geographical variations in diet, population density, sanitation, and education may also contribute (15). Additionally, prior antibiotic use, common for various infections in Uganda, may have partially or fully eradicated H. pylori in some patients (19, 20). Antibiotics can also alter H. pylori morphology, complicating microscopic detection despite its presence (21) A statistically significant association emerged between H. pylori infection density and the severity of histopathological features, including chronic inflammation, neutrophil activity, glandular atrophy, and intestinal metaplasia (all p<0.05). Patients with moderate to severe H. pylori infection exhibited a higher prevalence of severe chronic inflammation, consistent with prior research (22, 23). The predominance of T-cell-mediated mononuclear infiltrates, influenced by host immune status, supports a dose-response relationship where higher bacterial density correlates with increased histopathological severity (24). These findings echo studies from Egypt, Iran, Japan, and the United States, which link higher H. pylori loads to robust immune responses, persistent mucosal inflammation, glandular damage, atrophy, and intestinal metaplasia (4, 22-24). Most patients in this study had mild H. pylori infection but moderate chronic inflammation, while those with moderate to severe infection predominantly showed severe inflammation. Proinflammatory cytokines, such as IL-8, drive neutrophil recruitment, contributing to this progression (4). Neutrophilic infiltration, a hallmark of active gastritis, was strongly associated with high-density H. pylori infection, reflecting host responses to virulent factors like VacA and CagA, which exert cytotoxic effects on epithelial cells (2, 4). The significant association with intestinal metaplasia suggests that high H. pylori density promotes precancerous changes, increasing risks for gastric neoplasia (25, 26). The study identified a statistically significant association between H. pylori infection and age groups (p=0.032), with the highest prevalence among adults aged 19–59 years (34.8%), followed by those aged 60 years and older (15.2%), and none in children aged 5–18 years, contrasting with studies finding no age association (27, 28). Higher prevalence in adults may reflect cumulative exposure, lifestyle factors, occupational risks, or limited healthcare access (29). Lower prevalence in older adults could result from spontaneous clearance, prior antibiotic treatment, or age-related mucosal atrophy reducing bacterial colonization. The absence of infection in children, unlike studies reporting significant pediatric prevalence (30, 31), may stem from their underrepresentation in the sample, possibly due to fewer pediatric endoscopies, or prior antibiotic exposure (32). These results suggest H. pylori acquisition often occurs in childhood but persists and is most detectable in adulthood (12), supporting targeted screening for adults aged 19–59 years to prevent chronic gastritis and its complications. A slightly higher H. pylori prevalence was observed in males (30.0%) compared to females (26.7%), though not statistically significant (p=0.796), aligning with studies reporting similar trends (12, 33, 34). Male predominance may arise from lifestyle behaviors, such as eating in less hygienic settings, or exposure to risk factors like alcohol and tobacco (11, 15, 20, 35). This trend appeared only in adults, reinforcing the role of adult-specific exposures (36). The lack of statistical significance, consistent with other studies (15, 37), suggests minimal sex-based differences, indicating that sex-specific interventions may not be necessary. Limitations This study faced limitations that may affect its findings. The cross-sectional design precluded establishing causality, such as whether severe H. pylori infection drives severe inflammation. Histological detection risked missing low-density infections, potentially leading to misdiagnosis. Additionally, H. pylori ’s coccoid form under environmental stress hinders accurate identification. Prior use of antibiotics or proton pump inhibitors, common in Uganda, likely altered bacterial visibility, underestimating prevalence. Although standardized protocols and expert review reduced errors, longitudinal studies with molecular detection and detailed treatment histories could better elucidate H. pylori ’s role in chronic gastritis in Uganda. 5. Conclusion This study found a 29.3% prevalence of Helicobacter pylori infection in Ugandan chronic gastritis patients, mostly with mild density. Infection density significantly correlated with age, severe inflammation, neutrophil activity, glandular atrophy, and intestinal metaplasia, but not sex, highlighting the need for targeted screening and eradication efforts. List of abbreviations FFPE: Formalin fixed and paraffin-Embedded. H&E: Hematoxylin and Eosin H. pylori: Helicobacter pylori. IARC: International Agency for Research on Cancer MNRH: Mulago National Referral Hospital S: Supplementary file SBSREC: School of Biomedical Sciences Research and Ethics Committee. UCI: Uganda Cancer Institute. Declarations Ethics approval and consent to participate Ethical approval (SBS-2024-593) was granted by the School of Biomedical Sciences Research and Ethics Committee (SBS-REC) to conduct this study at the Departments of Pathology, Makerere University College of Health Sciences, Mulago National Referral Hospital, and the Uganda Cancer Institute ( Supplement 6 ). Additionally, a waiver of informed consent was obtained ( Supplement 7 ), ensuring compliance with ethical standards for the use of archived formalin-fixed paraffin-embedded tissue samples. Availability of data and materials The data supporting the findings of this study are available upon request from the corresponding author. Competing interests The authors declare that they have no competing interests. Funding This study received no external funding. Authors' contributions O.M.M. conceptualized and designed the study, collected and managed data, conducted the analysis, and drafted and revised the manuscript. O.P., A.I., B.E.C., W.E.F., M.A., B.M., M.S., L.R., B.P., and K.S. contributed to the study’s conceptualization, design, data collection, analysis, and manuscript revisions. B.M. critically proofread and edited the final manuscript. M.A., B.P., and K.S. provided project supervision. All authors reviewed and approved the final manuscript for submission. Acknowledgements The authors express sincere gratitude to the laboratory staff at the Department of Pathology, Makerere University, Mulago National Referral Hospital, and the Uganda Cancer Institute for their invaluable technical expertise and support throughout the study. References Dixon MF, Genta RM, Yardley JH, Correa P. Classification and grading of gastritis: the updated Sydney system. The American journal of surgical pathology. 1996;20(10):1161-81. Watari J, Chen N, Amenta PS, Fukui H, Oshima T, Tomita T, et al. Helicobacter pylori associated chronic gastritis, clinical syndromes, precancerous lesions, and pathogenesis of gastric cancer development. World Journal of Gastroenterology: WJG. 2014;20(18):5461. Sipponen P, Kosunen T, Valle J, Riihelä M, Seppälä K. Helicobacter pylori infection and chronic gastritis in gastric cancer. Journal of clinical pathology. 1992;45(4):319-23. Figueiredo C, Machado JC, Yamaoka Y. Pathogenesis of Helicobacter pylori infection. 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Cancer causes & control. 2008;19:869-77. De Martel C, Parsonnet J. Helicobacter pylori infection and gender: a meta-analysis of population-based prevalence surveys. Digestive diseases and sciences. 2006;51:2292-301. Khalifa MM, Sharaf RR, Aziz RK. Helicobacter pylori: a poor man's gut pathogen? Gut pathogens. 2010;2:1-12. Tables Table 1 : Summary demographic characteristics of patients with chronic gastritis Characteristics Frequency (n) Proportion (%) Age 5-18years 5 3.3 19-59years 112 74.7 ≥60 years 33 20.0 Sex Male 90 60.0 Female 60 40.0 Table 2 : Summary histologic characteristics of patients with chronic gastritis Characteristics Frequency (n) Proportion (%) Chronic inflammation Mild 39 26.0 Moderate 83 55.3 Severe 28 18.7 Neutrophil activity None Mild 60 38 40.0 25.3 Moderate Severe 42 10 28.0 6.7 Glandular atrophy None 101 67.3 Mild Moderate Severe 34 12 3 22.7 8.0 2.0 Intestinal metaplasia None 139 92.7 Mild 11 7.3 H. Pylori infection None Mild Moderate 106 13 26 70.7 8.7 17.3 Severe 5 3.3 Table 3 : Association of H. pylori density and histopathological characteristics of chronic gastritis. Histopathology H. pylori density Chi Square test p-Value Characteristic Category None. Freq. (%) Mild. Freq. (%) Moderate and severe. Freq (%) Chronic Inflammation Mild 2 (66.7) 0 (0.0) 1 (33.3) 59.8 <0.001 Moderate 99 (85.3) 7 (6.0) 10 (8.6) Severe 5 (16.1) 6 (19.4) 20 (64.5) Neutrophil Activity None 46 (95.8) 0 (0.0) 2 (4.2) 28.1 <0.001 Mild 59 (60.2) 13 (13.3) 26 (26.5) Moderate 1 (33.3) 0 (0.0) 2 (66.7) Severe 0 (0.0) 0 (0.0) 1 (100.0) Glandular Atrophy None 41 (67.2) 5 (8.2) 15 (24.6) 17.1 0.009 Mild 60 (75.9) 4 (5.1) 15 (19.0) Moderate 4 (44.4) 4 (44.4) 1 (11.1) Severe 1 (100.0) 0 (0.0) 0 (0.0) Intestinal Metaplasia None 104 (74.8) 10 (7.2) 25 (18.0) 16.0 <0.001 Mild 2 (18.2) 3 (27.3) 6 (54.5) Table 4 : The association between H. pylori infection and age groups. H. pylori infection Age groups Chi-square 5 – 18 (n=5) 19 – 59 (n=112) ≥ 60 (n=33 ) Present 0 (0.0) 39 (34.8%) 5 (15.2%) 6.9 Absent 5 (100.0) 73 (65.2) 28 (84.8%) p-Value 0.032 Table 5 : The association between H. pylori infection and sex. H. pylori infection Sex Chi- Square Male (n= 90) Female (n=60 ) Present 27 (30.0%) 16 (26.7%) 0.067 Absent 63 (70.0%) 44 (73.3%) p-Value 0.796 Table 6 : Bivariable analysis of factors associated with presence of H. pylori infection density in chronic gastritis. Table 7 : Multivariate analysis of factors associated with H. Pylori infection density in Chronic gastritis Characteristics (%) Crude Odds ratio Adjusted Odds ratio (95% CI) P-value Age 19-59 years (34.8) 1 ≥60 years (15.2) 0.33 Sex Male (60.0) 1 1 Female (40.0) 0.8 0.4 (0.56-9.40) 0.247 Chronic inflammation Mild (26.0) 1 1 Moderate (55.3) 9.8 2.5 (0.27-23.25) 0.414 Severe (18.7) 494 215 (14.45-3221.87) <0.001 Neutrophil activity None (40.0) 1 1 Mild to severe (60.0) 25.4 12.6 (1.87-84.35) 0.009 Glandular atrophy None (67.3) 1 1 Mild to severe (32.7) 4.5 0.96 (0.30-3.18) 0.966 Intestinal metaplasia None (92.7) 1 1 Mild (7.3) 13.4 11.6 (1.05-126.69) 0.045 Additional Declarations No competing interests reported. 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This histopathological profile leads to a wide range of clinical outcomes, from mild abdominal discomfort to severe complications such as peptic ulcers, gastric atrophy, intestinal metaplasia, gastric adenocarcinoma, and mucosa-associated lymphoid tissue (MALT) lymphoma(2-4). Affecting over half of the global population, chronic gastritis represents a major public health burden, particularly in regions with limited healthcare infrastructure (5).\u003c/p\u003e\n\u003cp\u003eThe leading cause of chronic gastritis is \u003cem\u003eHelicobacter pylori\u003c/em\u003e (\u003cem\u003eH. pylori\u003c/em\u003e), a Gram-negative, spiral-shaped, motile bacterium uniquely adapted to thrive in the stomach\u0026rsquo;s acidic, microaerophilic environment (6). Through mechanisms such as urease enzyme secretion, which neutralizes gastric acid, and multiple flagella that enable motility, \u003cem\u003eH. pylori\u003c/em\u003e effectively colonizes the gastric mucosa (7). Its prevalence is alarmingly high in developing countries, where inadequate sanitation and healthcare access facilitate its spread (3). In Africa, infection rates often exceed 70%, driven by early childhood acquisition, including mother-to-child transmission (8, 9). Socioeconomic challenges, such as poor hygiene and limited healthcare resources, further exacerbate infection rates in low-income regions compared to developed nations (10, 11). In Uganda, high rates of \u003cem\u003eH. pylori\u003c/em\u003e infection have been documented, with studies reporting positive stool antigen tests among patients in Kampala, yet detailed insights into associated demographic and histopathological characteristics remain scarce (12).\u003c/p\u003e\n\u003cp\u003eChronic gastritis driven by \u003cem\u003eH. pylori\u003c/em\u003e significantly increases the risk of severe gastrointestinal complications. Approximately 10% of affected individuals develop peptic ulcer disease, while 1\u0026ndash;3% progress to gastric cancers, including adenocarcinoma, due to the bacterium\u0026rsquo;s carcinogenic properties . Classified as a Group 1 carcinogen by the International Agency for Research on Cancer (IARC), \u003cem\u003eH. pylori\u003c/em\u003e is a key contributor to gastric cancer development (6, 13). The global rise in antibiotic resistance further complicates treatment, amplifying morbidity and mortality (14).\u003c/p\u003e\n\u003cp\u003eIn resource-constrained settings like Uganda, where \u003cem\u003eH. pylori\u003c/em\u003e prevalence is high, understanding its epidemiology and histopathological impact is essential for designing effective prevention and treatment strategies. This study aimed to determine the prevalence of \u003cem\u003eH. pylori\u003c/em\u003e infection and characterize its associated demographic and histopathological features among patients diagnosed with chronic gastritis in Uganda.\u003c/p\u003e"},{"header":"2.\tMethods","content":"\u003cp\u003e\u003cstrong\u003e2.1 Study Design and Setting\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThis study was a cross-sectional, laboratory-based investigation with a retrospective approach, aimed at determining the prevalence of \u003cem\u003eHelicobacter pylori\u003c/em\u003e (\u003cem\u003eH. pylori\u003c/em\u003e) infection and characterizing its associated demographic and histopathological features in patients diagnosed with chronic gastritis in Uganda. The study was conducted at the pathology departments of Mulago National Referral Hospital (MNRH), Makerere University, and the Uganda Cancer Institute (UCI) in Kampala, Uganda\u0026rsquo;s capital city. These national reference centers provide diagnostic cytology, histopathology, and autopsy services, processing approximately 20,000 tissue biopsies annually, including around 50 formalin-fixed paraffin-embedded (FFPE) blocks diagnosed with chronic gastritis per year.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e2.2 Study Population\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThe study population comprised FFPE tissue blocks from patients with a histologically confirmed diagnosis of chronic gastritis, archived at the pathology departments of MNRH, Makerere University, and UCI between September 2018 and August 2021. A total of 150 blocks were included, representing patients aged 5 years and older, with request forms documenting age and sex.\u003c/p\u003e\n\u003cp\u003e\u003cem\u003eInclusion Criteria\u003c/em\u003e\u003c/p\u003e\n\u003col\u003e\n \u003cli\u003eFFPE tissue blocks with histologically confirmed chronic gastritis and accompanying request forms specifying age and sex.\u003c/li\u003e\n \u003cli\u003eBlocks from patients aged 5 years and older.\u003c/li\u003e\n\u003c/ol\u003e\n\u003cp\u003e\u003cem\u003eExclusion Criteria\u003c/em\u003e\u003c/p\u003e\n\u003col class=\"decimal_type\"\u003e\n \u003cli\u003eBlocks with inadequate or depleted tissue.\u003c/li\u003e\n \u003cli\u003eBlocks diagnosed with gastric carcinoma or mucosa-associated lymphoid tissue (MALT) lymphoma.\u003c/li\u003e\n \u003cli\u003eExtensively damaged blocks.\u003c/li\u003e\n \u003cli\u003eBlocks with incomplete patient information (e.g., missing age or sex).\u003c/li\u003e\n \u003cli\u003eBlocks with extensive necrosis.\u003c/li\u003e\n\u003c/ol\u003e\n\u003cp\u003e\u003cstrong\u003e2.3 Sample Size Calculation\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThe sample size was calculated using the Kish-Leslie formula (Kish, 1965):\u0026nbsp;\u003c/p\u003e\n\u003cp\u003e\u003cimg width=\"134\" height=\"41\" src=\"data:image/png;base64,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\" alt=\"image\"\u003e\u003c/p\u003e\n\u003cp\u003eWhere:\u003c/p\u003e\n\u003col\u003e\n \u003cli\u003eN = Sample size\u003c/li\u003e\n \u003cli\u003eZ= Standard normal deviation at a 95% confidence interval, corresponding to 1.96\u003c/li\u003e\n \u003cli\u003eP = Estimated proportion of \u003cem\u003eH. pylori\u003c/em\u003e infection in chronic gastritis cases (set at 0.5 due to unknown prevalence in Uganda)\u003c/li\u003e\n \u003cli\u003eE = Margin of error accepted in this study, set at 5% (0.05).\u003c/li\u003e\n\u003c/ol\u003e\n\u003cp\u003eDue to the limited availability of 150 eligible FFPE blocks, all were analyzed. While this sample size is below the calculated 384, it was deemed sufficient for exploratory analysis given the constrained population.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e2.4 Sample Collection and Processing\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e2.4.1 Sample Collection\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eFFPE tissue blocks were retrieved from the archives of MNRH, Makerere University, and UCI pathology departments. Blocks were selected based on a histological diagnosis of chronic gastritis from September 2018 to August 2021. Each block was uniquely labeled to ensure accurate identification.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e2.4.2 Sample Processing\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eTwo 4-micrometer sections were cut from each FFPE block using standard histological techniques (\u003cstrong\u003eSupplement 1\u003c/strong\u003e). One section was stained with hematoxylin and eosin (H\u0026amp;E) to confirm the chronic gastritis diagnosis (\u003cstrong\u003eSupplement 2\u003c/strong\u003e). The second section was stained with modified Giemsa to detect \u003cem\u003eH. pylori\u003c/em\u003e, identified by its purple or pink spiral/curved morphology against a blue background (\u003cstrong\u003eSupplement 3\u003c/strong\u003e). Staining was performed by the principal investigator (PI) with assistance from a qualified laboratory technician, following standardized protocols.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e2.4.3 Histopathological Evaluation\u003c/strong\u003e\u003c/p\u003e\n\u003col class=\"decimal_type\"\u003e\n \u003cli\u003eH\u0026amp;E-Stained Slides were examined using light microscope grading; chronic inflammation, neutrophil activity, glandular atrophy, and intestinal metaplasia using the Modified Sydney System (1) on a scale of 0 (none) to 3 (severe) (S4). Intestinal metaplasia was identified by goblet and absorptive cells, and \u003cem\u003eH. pylori\u003c/em\u003e density was quantified based on bacterial presence on the surface epithelium. Supervising pathologists confirmed the findings.\u003c/li\u003e\n \u003cli\u003eModified Giemsa-Stained Slides: The PI evaluated slides under oil immersion (100x magnification) for \u003cem\u003eH. pylori\u003c/em\u003e. Supervising pathologists verified results. Digital images were captured using a Nikon Eclipse Ci-L multi-header microscope for documentation.\u003c/li\u003e\n\u003c/ol\u003e\n\u003cp\u003e\u003cstrong\u003e2.5 Data Collection\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eData were collected using paper-based forms (\u003cstrong\u003eSupplement 5\u003c/strong\u003e), with each block assigned a unique case number to ensure confidentiality. Patient names and biopsy numbers were excluded. The PI recorded histopathological findings (\u003cem\u003eH. pylori\u003c/em\u003e presence, density, and characteristics such as chronic inflammation, neutrophil activity, glandular atrophy, and intestinal metaplasia) and demographic data (age, sex). Supervising pathologists independently reviewed the slides, and discrepancies were resolved via collaborative review on a multi-header microscope.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e2.6 Statistical Analysis\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eData were entered into Microsoft Excel, cleaned, and transferred to Stata version 17.0 (StataCorp) for analysis. Normality was assessed using the Shapiro-Wilk test. A qualified biostatistician conducted the analysis. The prevalence of \u003cem\u003eH. pylori\u003c/em\u003e infection was calculated as a proportion. Continuous variables (e.g., \u003cem\u003eH. pylori\u003c/em\u003e density) were summarized as means with standard deviations (SD). Categorical variables (e.g., chronic inflammation severity, neutrophil activity, glandular atrophy, intestinal metaplasia, sex, age, and \u003cem\u003eH. pylori\u003c/em\u003e presence) were reported as frequencies and percentages in tables.\u003c/p\u003e\n\u003cp\u003eChi-square tests with p-values evaluated associations between \u003cem\u003eH. pylori\u003c/em\u003e infection and independent variables (demographic and histopathological characteristics). Bivariate logistic regression calculated crude odds ratios (ORs). Multivariate logistic regression included all variables to compute adjusted ORs and assess confounding, defined as a \u0026gt;10% change between crude and adjusted ORs for significant variables. Statistical significance was set at a 95% confidence interval and p \u0026le; 0.05. Results were presented using descriptive text and tables.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e2.7 Quality Control\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eStandard operating procedures were adhered to throughout the study. Slides were carefully mounted to prevent detachment or artifacts. H\u0026amp;E and modified Giemsa staining followed standardized protocols (\u003cstrong\u003eSupplement 2\u003c/strong\u003e and \u003cstrong\u003eSupplement 3\u003c/strong\u003e), with positive and negative controls (known \u003cem\u003eH. pylori\u003c/em\u003e-positive and -negative cases) included in each batch to ensure accuracy. Staining quality was assessed for clarity, uniformity, and absence of artifacts. Issues prompted repeat staining with fresh reagents. The PI and two supervising pathologists, blinded to age and sex, independently reviewed slides to minimize bias. Discrepancies were resolved collaboratively. Data analysis was supported by an experienced biostatistician to ensure accuracy.\u003c/p\u003e"},{"header":"3.\tResults","content":"\u003cp\u003e\u003cstrong\u003e3.1 Demographic and Histopathological Characteristics of Patients\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eA total of 150 formalin-fixed paraffin-embedded (FFPE) tissue specimens from patients diagnosed with chronic gastritis were analyzed. The patients ranged in age from 12 to 89 years, with a mean age of 48 years (standard deviation [SD] = 17 years) and a median age of 47 years (interquartile range [IQR] = 38\u0026ndash;58 years). Males comprised 60% (n=90) of the study population, while females accounted for 40% (n=60), as shown in\u0026nbsp;\u003cstrong\u003e\u003cem\u003eTable 1\u003c/em\u003e\u003c/strong\u003e.\u003c/p\u003e\n\u003cp\u003eHistopathological characteristics, assessed using the Modified Sydney System, included chronic inflammation, neutrophil activity, glandular atrophy, intestinal metaplasia, and dysplasia. Chronic inflammation was predominantly moderate (55.3%, n=83), while neutrophil activity was mild in 25.3% (n=38) of cases, with 40.0% (n=60) showing no activity. Glandular atrophy was absent in 67.3% (n=101) of cases, and intestinal metaplasia was absent in 92.7% (n=139). \u003cem\u003eH. pylori\u003c/em\u003e infection density was moderate in 17.3% (n=26) of cases, with 70.7% (n=106) showing no infection. Dysplasia, observed in a subset of cases, was mild in most instances. These findings are summarized in\u0026nbsp;\u003cstrong\u003eTable 2\u003c/strong\u003e. Representative photomicrographs of histopathological findings are presented as \u0026nbsp;\u003cstrong\u003ePlate 1\u003c/strong\u003e,\u0026nbsp;\u003cstrong\u003ePlate 2\u003c/strong\u003e,\u0026nbsp;\u003cstrong\u003ePlate 3\u003c/strong\u003e,\u0026nbsp;\u003cstrong\u003ePlate 4\u003c/strong\u003e,\u0026nbsp;\u003cstrong\u003ePlate 5\u003c/strong\u003e,\u0026nbsp;\u003cstrong\u003ePlate 6\u003c/strong\u003e and\u0026nbsp;\u003cstrong\u003ePlate 7\u003c/strong\u003e:\u0026nbsp;\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e3.2 Prevalence and Density of H. pylori Infection\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eOf the 150 patients, 44 (29.3%) tested positive for \u003cem\u003eH. pylori\u003c/em\u003e infection, yielding a prevalence of 29.3%. Among those with \u003cem\u003eH. pylori\u003c/em\u003e infection, the density was mild in 8.7% (n=13), moderate in 17.3% (n=26), and severe in 3.3% (n=5).\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e3.3 Association Between H. pylori Infection Density and Histopathological Features\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eA strong correlation was observed between \u003cem\u003eH. pylori\u003c/em\u003e infection density and histopathological characteristics, including chronic inflammation (p\u0026lt;0.001), neutrophil activity (p\u0026lt;0.001), glandular atrophy (p=0.009), and intestinal metaplasia (p\u0026lt;0.001). These associations, assessed using Chi-square tests, are detailed in\u0026nbsp;\u003cstrong\u003eTable 3\u003c/strong\u003e.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e3.4 Association Between H. pylori Infection and Age\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eA statistically significant association was found between \u003cem\u003eH. pylori\u003c/em\u003e infection and age groups (p=0.032). The infection was most prevalent in the 19\u0026ndash;59 years age group (34.8%, n=39), compared to 15.2% (n=5) in those \u0026ge;60 years and 0% (n=0) in the 5\u0026ndash;18 years group as shown in\u0026nbsp;\u003cstrong\u003eTable 4\u003c/strong\u003e.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e3.5 Association Between \u003cem\u003eH. pylori\u003c/em\u003e Infection and Sex\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eNo statistically significant association was observed between \u003cem\u003eH. pylori\u003c/em\u003e infection and sex (p=0.796). Infection rates were slightly higher in males (30.0%, n=27) than in females (26.7%, n=16), but the difference was not significant as shown in\u0026nbsp;\u003cstrong\u003eTable 5\u003c/strong\u003e.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e3.6 Factors Associated with \u003cem\u003eH. pylori\u003c/em\u003e Infection\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e3.6.1 Bivariate Analysis\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eBivariate logistic regression revealed significant associations between \u003cem\u003eHelicobacter pylori\u003c/em\u003e infection and several factors. Compared to the 19\u0026ndash;59 years age group, patients aged 60 years and older had lower odds of infection (crude odds ratio [OR]=0.33, p=0.033). The odds of infection were slightly lower in females compared to males (crude OR=0.85, p=0.658), but this difference was not statistically significant. The odds of \u003cem\u003eH. pylori\u003c/em\u003e infection increased significantly with moderate chronic inflammation (crude OR=9.8, p=0.030) and severe chronic inflammation (crude OR=494, p\u0026lt;0.001) compared to mild inflammation, mild to severe neutrophil activity (crude OR=25.4, p\u0026lt;0.001) compared to no activity, mild to severe glandular atrophy (crude OR=4.5, p\u0026lt;0.001) compared to no atrophy, and mild intestinal metaplasia (crude OR=13.4, p=0.001) compared to no metaplasia, as summarized in\u0026nbsp;\u003cstrong\u003eTable 6\u003c/strong\u003e.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e3.6.2 Multivariate Logistic Regression Analysis\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eMultivariate logistic regression, adjusting for all variables, identified independent factors associated with \u003cem\u003eHelicobacter pylori\u003c/em\u003e infection, as summarized in\u0026nbsp;\u003cstrong\u003eTable 7\u003c/strong\u003e. The adjusted odds ratios (AORs) were 215 (95% confidence interval [CI]: 14.45\u0026ndash;3221.87, p\u0026lt;0.001) for severe chronic inflammation compared to mild inflammation, 12.6 (95% CI: 1.87\u0026ndash;84.35, p=0.009) for mild to severe neutrophil activity compared to no activity, and 11.6 (95% CI: 1.05\u0026ndash;126.69, p=0.045) for mild intestinal metaplasia compared to no metaplasia. Age, sex, and glandular atrophy were not significantly associated with \u003cem\u003eH. pylori\u003c/em\u003e infection in the multivariate model.\u003c/p\u003e"},{"header":"4. Discussion","content":"\u003cp\u003eThis study examined the prevalence of Helicobacter pylori (H. pylori) infection and its associated demographic and histopathological characteristics among 150 patients with chronic gastritis in Uganda, offering valuable insights into its epidemiology in a resource-limited setting. The findings revealed a prevalence of 29.3% for H. pylori infection, with generally mild bacterial density, aligning closely with global estimates, such as 34.7% reported in a prior study (15), but exceeding the 16.8% observed in Italy (16). However, this prevalence is notably lower than the 40\u0026ndash;70% reported in other African regions (15, 17, 18).\u0026nbsp;A global analysis across 111 countries documented a 15.9% decline in H. pylori prevalence over recent decades, particularly in adults in Africa (19)\u0026nbsp; Several factors may explain this lower prevalence in Uganda. Enhanced public health measures, including improved sanitation, access to clean water, and better hygiene practices, likely reduced H. pylori transmission, especially in urbanizing areas. Geographical variations in diet, population density, sanitation, and education may also contribute (15). Additionally, prior antibiotic use, common for various infections in Uganda, may have partially or fully eradicated H. pylori in some patients (19, 20). Antibiotics can also alter H. pylori morphology, complicating microscopic detection despite its presence (21)\u003c/p\u003e\n\u003cp\u003eA statistically significant association emerged between H. pylori infection density and the severity of histopathological features, including chronic inflammation, neutrophil activity, glandular atrophy, and intestinal metaplasia (all p\u0026lt;0.05). Patients with moderate to severe H. pylori infection exhibited a higher prevalence of severe chronic inflammation, consistent with prior research (22, 23). The predominance of T-cell-mediated mononuclear infiltrates, influenced by host immune status, supports a dose-response relationship where higher bacterial density correlates with increased histopathological severity (24). These findings echo studies from Egypt, Iran, Japan, and the United States, which link higher H. pylori loads to robust immune responses, persistent mucosal inflammation, glandular damage, atrophy, and intestinal metaplasia (4, 22-24). Most patients in this study had mild H. pylori infection but moderate chronic inflammation, while those with moderate to severe infection predominantly showed severe inflammation. Proinflammatory cytokines, such as IL-8, drive neutrophil recruitment, contributing to this progression (4). Neutrophilic infiltration, a hallmark of active gastritis, was strongly associated with high-density H. pylori infection, reflecting host responses to virulent factors like VacA and CagA, which exert cytotoxic effects on epithelial cells (2, 4). The significant association with intestinal metaplasia suggests that high H. pylori density promotes precancerous changes, increasing risks for gastric neoplasia (25, 26).\u003c/p\u003e\n\u003cp\u003eThe study identified a statistically significant association between H. pylori infection and age groups (p=0.032), with the highest prevalence among adults aged 19\u0026ndash;59 years (34.8%), followed by those aged 60 years and older (15.2%), and none in children aged 5\u0026ndash;18 years, contrasting with studies finding no age association (27, 28). Higher prevalence in adults may reflect cumulative exposure, lifestyle factors, occupational risks, or limited healthcare access (29). Lower prevalence in older adults could result from spontaneous clearance, prior antibiotic treatment, or age-related mucosal atrophy reducing bacterial colonization. The absence of infection in children, unlike studies reporting significant pediatric prevalence (30, 31), may stem from their underrepresentation in the sample, possibly due to fewer pediatric endoscopies, or prior antibiotic exposure (32). These results suggest H. pylori acquisition often occurs in childhood but persists and is most detectable in adulthood (12), supporting targeted screening for adults aged 19\u0026ndash;59 years to prevent chronic gastritis and its complications.\u003c/p\u003e\n\u003cp\u003eA slightly higher H. pylori prevalence was observed in males (30.0%) compared to females (26.7%), though not statistically significant (p=0.796), aligning with studies reporting similar trends (12, 33, 34). Male predominance may arise from lifestyle behaviors, such as eating in less hygienic settings, or exposure to risk factors like alcohol and tobacco (11, 15, 20, 35). This trend appeared only in adults, reinforcing the role of adult-specific exposures (36). The lack of statistical significance, consistent with other studies (15, 37), suggests minimal sex-based differences, indicating that sex-specific interventions may not be necessary.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cem\u003eLimitations\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThis study faced limitations that may affect its findings. The cross-sectional design precluded establishing causality, such as whether severe \u003cem\u003eH. pylori\u003c/em\u003e infection drives severe inflammation. Histological detection risked missing low-density infections, potentially leading to misdiagnosis. Additionally, \u003cem\u003eH. pylori\u003c/em\u003e\u0026rsquo;s coccoid form under environmental stress hinders accurate identification. Prior use of antibiotics or proton pump inhibitors, common in Uganda, likely altered bacterial visibility, underestimating prevalence. Although standardized protocols and expert review reduced errors, longitudinal studies with molecular detection and detailed treatment histories could better elucidate \u003cem\u003eH. pylori\u003c/em\u003e\u0026rsquo;s role in chronic gastritis in Uganda.\u003c/p\u003e"},{"header":"5. Conclusion","content":"\u003cp\u003eThis study found a 29.3% prevalence of \u003cem\u003eHelicobacter pylori\u003c/em\u003e infection in Ugandan chronic gastritis patients, mostly with mild density. Infection density significantly correlated with age, severe inflammation, neutrophil activity, glandular atrophy, and intestinal metaplasia, but not sex, highlighting the need for targeted screening and eradication efforts.\u003c/p\u003e"},{"header":"List of abbreviations","content":"\u003cp\u003eFFPE:\u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp;\u0026nbsp;Formalin fixed and paraffin-Embedded.\u003c/p\u003e\n\u003cp\u003eH\u0026amp;E:\u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp;\u0026nbsp;Hematoxylin and Eosin\u003c/p\u003e\n\u003cp\u003e\u003cem\u003eH. pylori:\u003c/em\u003e \u003cem\u003eHelicobacter pylori.\u003c/em\u003e\u003c/p\u003e\n\u003cp\u003eIARC:\u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp;International Agency for Research on Cancer\u0026nbsp;\u003c/p\u003e\n\u003cp\u003eMNRH:\u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp;Mulago National Referral Hospital\u003c/p\u003e\n\u003cp\u003eS:\u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp;Supplementary file\u003c/p\u003e\n\u003cp\u003eSBSREC: \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp;School of Biomedical Sciences Research and Ethics Committee.\u003c/p\u003e\n\u003cp\u003eUCI: \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp; \u0026nbsp;Uganda Cancer Institute.\u003c/p\u003e"},{"header":"Declarations","content":"\u003cp\u003e\u003cstrong\u003e\u003cem\u003eEthics approval and consent to participate\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eEthical approval (SBS-2024-593) was granted by the School of Biomedical Sciences Research and Ethics Committee (SBS-REC) to conduct this study at the Departments of Pathology, Makerere University College of Health Sciences, Mulago National Referral Hospital, and the Uganda Cancer Institute (\u003cstrong\u003eSupplement 6\u003c/strong\u003e). Additionally, a waiver of informed consent was obtained (\u003cstrong\u003eSupplement 7\u003c/strong\u003e), ensuring compliance with ethical standards for the use of archived formalin-fixed paraffin-embedded tissue samples.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cem\u003eAvailability of data and materials\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThe data supporting the findings of this study are available upon request from the corresponding author.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cem\u003eCompeting interests\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThe authors declare that they have no competing interests.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cem\u003eFunding\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThis study received no external funding.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cem\u003eAuthors\u0026apos; contributions\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eO.M.M. conceptualized and designed the study, collected and managed data, conducted the analysis, and drafted and revised the manuscript. O.P., A.I., B.E.C., W.E.F., M.A., B.M., M.S., L.R., B.P., and K.S. contributed to the study\u0026rsquo;s conceptualization, design, data collection, analysis, and manuscript revisions. B.M. critically proofread and edited the final manuscript. M.A., B.P., and K.S. provided project supervision. All authors reviewed and approved the final manuscript for submission.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003e\u003cem\u003eAcknowledgements\u003c/em\u003e\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThe authors express sincere gratitude to the laboratory staff at the Department of Pathology, Makerere University, Mulago National Referral Hospital, and the Uganda Cancer Institute for their invaluable technical expertise and support throughout the study.\u003c/p\u003e"},{"header":"References","content":"\u003col\u003e\n\u003cli\u003eDixon MF, Genta RM, Yardley JH, Correa P. Classification and grading of gastritis: the updated Sydney system. 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Journal of Tropical Medicine. 2021;2021(1):9935142.\u003c/li\u003e\n\u003cli\u003eO\u0026apos;Keefe SJ, Salvador B, Nainkin J, Majiki S, Stevens H, Atherstone A. Empiric treatment based on Helicobacter Pylori serology cannont substitute for early endoscopy in the management of dyspeptic rural black africans. South African Medical Journal. 2000;90(11).\u003c/li\u003e\n\u003cli\u003eAngol DC, Ocama P, Ayazika Kirabo T, Okeng A, Najjingo I, Bwanga F. Helicobacter pylori from peptic ulcer patients in Uganda is highly resistant to clarithromycin and fluoroquinolones: results of the GenoType HelicoDR test directly applied on stool. BioMed research international. 2017;2017(1):5430723.\u003c/li\u003e\n\u003cli\u003eZamani M, Ebrahimtabar F, Zamani V, Miller W, Alizadeh‐Navaei R, Shokri‐Shirvani J, et al. Systematic review with meta‐analysis: the worldwide prevalence of Helicobacter pylori infection. Alimentary pharmacology \u0026amp; therapeutics. 2018;47(7):868-76.\u003c/li\u003e\n\u003cli\u003eRibaldone DG, Zurlo C, Fagoonee S, Rosso C, Armandi A, Caviglia GP, et al. A Retrospective Experience of Helicobacter pylori Histology in a Large Sample of Subjects in Northern Italy. Life. 2021;11(7):650.\u003c/li\u003e\n\u003cli\u003eSmith S, Fowora M, Pellicano R. Infections with Helicobacter pylori and challenges encountered in Africa. World J Gastroenterol. 2019;25(25):3183-95.\u003c/li\u003e\n\u003cli\u003eHooi JK, Lai WY, Ng WK, Suen MM, Underwood FE, Tanyingoh D, et al. Global prevalence of Helicobacter pylori infection: systematic review and meta-analysis. Gastroenterology. 2017;153(2):420-9.\u003c/li\u003e\n\u003cli\u003eSalahi-Niri A, Nabavi-Rad A, Monaghan TM, Rokkas T, Doulberis M, Sadeghi A, et al. Global prevalence of Helicobacter pylori antibiotic resistance among children in the world health organization regions between 2000 and 2023: a systematic review and meta-analysis. BMC Medicine. 2024;22(1):598.\u003c/li\u003e\n\u003cli\u003eOling M, Odongo J, Kituuka O, Galukande M. Prevalence of Helicobacter pylori in dyspeptic patients at a tertiary hospital in a low resource setting. BMC research notes. 2015;8:1-6.\u003c/li\u003e\n\u003cli\u003eCheng T, Boneca IG. The shapeshifting Helicobacter pylori: From a corkscrew to a ball. Molecular Microbiology. 2024;121(2):260-74.\u003c/li\u003e\n\u003cli\u003eAli FA, Mahmoud SF, Said AA, Salah Elden EM. Lymphocytic infiltration in helicobacter pylori gastritis. SVU-International Journal of Medical Sciences. 2021;4(1):76-9.\u003c/li\u003e\n\u003cli\u003eGhasemi Basir HR, Ghobakhlou M, Akbari P, Dehghan A, Seif Rabiei MA. Correlation between the Intensity of Helicobacter pylori Colonization and Severity of Gastritis. Gastroenterol Res Pract. 2017;2017:8320496.\u003c/li\u003e\n\u003cli\u003eKumar S, Patel GK, Ghoshal UC. Helicobacter pylori-Induced Inflammation: Possible Factors Modulating the Risk of Gastric Cancer. Pathogens. 2021;10(9):1099.\u003c/li\u003e\n\u003cli\u003eWabinga H. Helicobacter pylori and histopathological changes of gastric mucosa in Uganda population with varying prevalence of stomach cancer. African health sciences. 2005;5(3):234-7.\u003c/li\u003e\n\u003cli\u003eWhitmire JM, Merrell DS. Helicobacter pylori Genetic Polymorphisms in Gastric Disease Development. In: Kamiya S, Backert S, editors. Helicobacter pylori in Human Diseases: Advances in Microbiology, Infectious Diseases and Public Health Volume 11. Cham: Springer International Publishing; 2019. p. 173-94.\u003c/li\u003e\n\u003cli\u003eAdlekha S, Chadha T, Krishnan P, Sumangala B. Prevalence of Helicobacter pylori infection among patients undergoing upper gastrointestinal endoscopy in a medical college hospital in Kerala, India. Annals of medical and health sciences research. 2013;3(4):559-63.\u003c/li\u003e\n\u003cli\u003eAlshareef SA, Hassan AA, Abdelrahman DN, AlEed A, Al-Nafeesah A, Adam I. The prevalence and associated factors of Helicobacter pylori infection among asymptomatic adolescent schoolchildren in Sudan: a cross-sectional study. BMC Pediatr. 2023;23(1):582.\u003c/li\u003e\n\u003cli\u003eChen R-x, Zhang D-y, Zhang X, Chen S, Huang S, Chen C, et al. A survey on Helicobacter pylori infection rate in Hainan Province and analysis of related risk factors. BMC Gastroenterology. 2023;23(1):338.\u003c/li\u003e\n\u003cli\u003eAitila P, Mutyaba M, Okeny S, Ndawula Kasule M, Kasule R, Ssedyabane F, et al. Prevalence and Risk Factors of Helicobacter pylori Infection among Children Aged 1 to 15 Years at Holy Innocents Children\u0026rsquo;s Hospital, Mbarara, South Western Uganda. Journal of Tropical Medicine. 2019;2019(1):9303072.\u003c/li\u003e\n\u003cli\u003eAnkarklev J, Hestvik E, Lebbad M, Lindh J, Kaddu-Mulindwa DH, Andersson JO, et al. Common coinfections of Giardia intestinalis and Helicobacter pylori in non-symptomatic Ugandan children. 2012.\u003c/li\u003e\n\u003cli\u003eDaugule I, Rowland M. Helicobacter pylori infection in children. Helicobacter. 2008;13:41-6.\u003c/li\u003e\n\u003cli\u003eIbrahim A, Morais S, Ferro A, Lunet N, Peleteiro B. Sex-differences in the prevalence of Helicobacter pylori infection in pediatric and adult populations: Systematic review and meta-analysis of 244 studies. Dig Liver Dis. 2017;49(7):742-9.\u003c/li\u003e\n\u003cli\u003eWu H-C, Tuo B-G, Wu W-M, Gao Y, Xu Q-Q, Zhao K. Prevalence of peptic ulcer in dyspeptic patients and the influence of age, sex, and Helicobacter pylori infection. Digestive diseases and sciences. 2008;53:2650-6.\u003c/li\u003e\n\u003cli\u003eEpplein M, Nomura AM, Hankin JH, Blaser MJ, Perez-Perez G, Stemmermann GN, et al. Association of Helicobacter pylori infection and diet on the risk of gastric cancer: a case\u0026ndash;control study in Hawaii. Cancer causes \u0026amp; control. 2008;19:869-77.\u003c/li\u003e\n\u003cli\u003eDe Martel C, Parsonnet J. Helicobacter pylori infection and gender: a meta-analysis of population-based prevalence surveys. Digestive diseases and sciences. 2006;51:2292-301.\u003c/li\u003e\n\u003cli\u003eKhalifa MM, Sharaf RR, Aziz RK. Helicobacter pylori: a poor man\u0026apos;s gut pathogen? Gut pathogens. 2010;2:1-12.\u003c/li\u003e\n\u003c/ol\u003e"},{"header":"Tables","content":"\u003cp\u003e\u003cstrong\u003eTable\u0026nbsp;\u003c/strong\u003e\u003cstrong\u003e1\u003c/strong\u003e\u003cstrong\u003e: Summary demographic characteristics of patients with chronic gastritis\u003c/strong\u003e\u003c/p\u003e\n\u003ctable border=\"0\" cellspacing=\"0\" cellpadding=\"0\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 47.4194%;\"\u003e\n \u003cp\u003e\u003cstrong\u003eCharacteristics\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 29.6774%;\"\u003e\n \u003cp\u003e\u003cstrong\u003eFrequency (n)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 22.9032%;\"\u003e\n \u003cp\u003e\u003cstrong\u003eProportion (%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 47.4194%;\"\u003e\n \u003cp\u003e\u003cstrong\u003eAge\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 29.6774%;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 22.9032%;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 47.4194%;\"\u003e\n \u003cp\u003e5-18years\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 29.6774%;\"\u003e\n \u003cp\u003e5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 22.9032%;\"\u003e\n \u003cp\u003e3.3\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 47.4194%;\"\u003e\n \u003cp\u003e19-59years\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 29.6774%;\"\u003e\n \u003cp\u003e112\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 22.9032%;\"\u003e\n \u003cp\u003e74.7\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 47.4194%;\"\u003e\n \u003cp\u003e\u0026ge;60 years\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 29.6774%;\"\u003e\n \u003cp\u003e33\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 22.9032%;\"\u003e\n \u003cp\u003e20.0\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 47.4194%;\"\u003e\n \u003cp\u003e\u003cstrong\u003eSex\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 29.6774%;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 22.9032%;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 47.4194%;\"\u003e\n \u003cp\u003eMale\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 29.6774%;\"\u003e\n \u003cp\u003e90\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 22.9032%;\"\u003e\n \u003cp\u003e60.0\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 47.4194%;\"\u003e\n \u003cp\u003eFemale\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 29.6774%;\"\u003e\n \u003cp\u003e60\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 22.9032%;\"\u003e\n \u003cp\u003e40.0\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp\u003e\u003cstrong\u003eTable\u0026nbsp;\u003c/strong\u003e\u003cstrong\u003e2\u003c/strong\u003e\u003cstrong\u003e: Summary histologic characteristics of patients with chronic gastritis\u003c/strong\u003e\u003c/p\u003e\n\u003ctable border=\"0\" cellspacing=\"0\" cellpadding=\"0\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 47.4194%;\"\u003e\n \u003cp\u003e\u003cstrong\u003eCharacteristics\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 29.6774%;\"\u003e\n \u003cp\u003e\u003cstrong\u003eFrequency (n)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 22.9032%;\"\u003e\n \u003cp\u003e\u003cstrong\u003eProportion (%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 47.4194%;\"\u003e\n \u003cp\u003e\u003cstrong\u003eChronic inflammation\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 29.6774%;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 22.9032%;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 47.4194%;\"\u003e\n \u003cp\u003eMild\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 29.6774%;\"\u003e\n \u003cp\u003e39\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 22.9032%;\"\u003e\n \u003cp\u003e26.0\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 47.4194%;\"\u003e\n \u003cp\u003eModerate\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 29.6774%;\"\u003e\n \u003cp\u003e83\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 22.9032%;\"\u003e\n \u003cp\u003e55.3\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 47.4194%;\"\u003e\n \u003cp\u003eSevere\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 29.6774%;\"\u003e\n \u003cp\u003e28\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 22.9032%;\"\u003e\n \u003cp\u003e18.7\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 47.4194%;\"\u003e\n \u003cp\u003e\u003cstrong\u003eNeutrophil activity\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 29.6774%;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 22.9032%;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 47.4194%;\"\u003e\n \u003cp\u003eNone\u003c/p\u003e\n \u003cp\u003eMild\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 29.6774%;\"\u003e\n \u003cp\u003e60\u003c/p\u003e\n \u003cp\u003e38\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 22.9032%;\"\u003e\n \u003cp\u003e40.0\u003c/p\u003e\n \u003cp\u003e25.3\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 47.4194%;\"\u003e\n \u003cp\u003eModerate\u0026nbsp;\u003c/p\u003e\n \u003cp\u003eSevere\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 29.6774%;\"\u003e\n \u003cp\u003e42\u003c/p\u003e\n \u003cp\u003e10\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 22.9032%;\"\u003e\n \u003cp\u003e28.0\u003c/p\u003e\n \u003cp\u003e6.7\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 47.4194%;\"\u003e\n \u003cp\u003e\u003cstrong\u003eGlandular atrophy\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 29.6774%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 22.9032%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 47.4194%;\"\u003e\n \u003cp\u003eNone\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 29.6774%;\"\u003e\n \u003cp\u003e101\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 22.9032%;\"\u003e\n \u003cp\u003e67.3\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 47.4194%;\"\u003e\n \u003cp\u003eMild\u003c/p\u003e\n \u003cp\u003eModerate\u0026nbsp;\u003c/p\u003e\n \u003cp\u003eSevere\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 29.6774%;\"\u003e\n \u003cp\u003e34\u003c/p\u003e\n \u003cp\u003e12\u003c/p\u003e\n \u003cp\u003e3\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 22.9032%;\"\u003e\n \u003cp\u003e22.7\u003c/p\u003e\n \u003cp\u003e8.0\u003c/p\u003e\n \u003cp\u003e2.0\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 47.4194%;\"\u003e\n \u003cp\u003e\u003cstrong\u003eIntestinal metaplasia\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 29.6774%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 22.9032%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 47.4194%;\"\u003e\n \u003cp\u003eNone\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 29.6774%;\"\u003e\n \u003cp\u003e139\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 22.9032%;\"\u003e\n \u003cp\u003e92.7\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 47.4194%;\"\u003e\n \u003cp\u003eMild\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 29.6774%;\"\u003e\n \u003cp\u003e11\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 22.9032%;\"\u003e\n \u003cp\u003e7.3\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 47.4194%;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003eH. Pylori\u003c/em\u003e\u003c/strong\u003e\u003cstrong\u003e\u0026nbsp;infection\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 29.6774%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 22.9032%;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 47.4194%;\"\u003e\n \u003cp\u003eNone\u003c/p\u003e\n \u003cp\u003eMild\u0026nbsp;\u003c/p\u003e\n \u003cp\u003eModerate\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 29.6774%;\"\u003e\n \u003cp\u003e106\u003c/p\u003e\n \u003cp\u003e13\u003c/p\u003e\n \u003cp\u003e26\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 22.9032%;\"\u003e\n \u003cp\u003e70.7\u003c/p\u003e\n \u003cp\u003e8.7\u003c/p\u003e\n \u003cp\u003e17.3\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 47.4194%;\"\u003e\n \u003cp\u003eSevere\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 29.6774%;\"\u003e\n \u003cp\u003e5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 22.9032%;\"\u003e\n \u003cp\u003e3.3\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp\u003e\u0026nbsp;\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eTable\u0026nbsp;\u003c/strong\u003e\u003cstrong\u003e3\u003c/strong\u003e\u003cstrong\u003e: Association of \u003cem\u003eH. pylori\u003c/em\u003e density and histopathological characteristics of chronic gastritis.\u003c/strong\u003e\u003c/p\u003e\n\u003ctable border=\"0\" cellspacing=\"0\" cellpadding=\"0\" width=\"623\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd colspan=\"2\" valign=\"top\" style=\"width: 179px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eHistopathology\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"3\" valign=\"top\" style=\"width: 274px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u003cem\u003eH. pylori\u003c/em\u003e\u003c/strong\u003e\u003cstrong\u003e\u0026nbsp;density\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" valign=\"top\" style=\"width: 85px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eChi Square test\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" valign=\"top\" style=\"width: 85px;\"\u003e\n \u003cp\u003e\u003cstrong\u003ep-Value\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 103px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eCharacteristic\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 76px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eCategory\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 85px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eNone.\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003e\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003e\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003e\u0026nbsp;Freq.\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003e(%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 85px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eMild.\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003e\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003e\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003eFreq.\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003e(%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 104px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eModerate and severe.\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003e\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003eFreq\u003c/strong\u003e\u003c/p\u003e\n \u003cp\u003e\u003cstrong\u003e(%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd rowspan=\"3\" valign=\"top\" style=\"width: 103px;\"\u003e\n \u003cp\u003eChronic Inflammation\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 76px;\"\u003e\n \u003cp\u003eMild\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 85px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003e(66.7)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 85px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003e(0.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 104px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003e(33.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"3\" valign=\"top\" style=\"width: 85px;\"\u003e\n \u003cp\u003e59.8\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"3\" valign=\"top\" style=\"width: 85px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u0026lt;0.001\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 76px;\"\u003e\n \u003cp\u003eModerate\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 85px;\"\u003e\n \u003cp\u003e99\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003e(85.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 85px;\"\u003e\n \u003cp\u003e7\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003e(6.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 104px;\"\u003e\n \u003cp\u003e10\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003e(8.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 76px;\"\u003e\n \u003cp\u003eSevere\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 85px;\"\u003e\n \u003cp\u003e5\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003e(16.1)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 85px;\"\u003e\n \u003cp\u003e6\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003e(19.4)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 104px;\"\u003e\n \u003cp\u003e20\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003e(64.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd rowspan=\"4\" valign=\"top\" style=\"width: 103px;\"\u003e\n \u003cp\u003eNeutrophil Activity\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 76px;\"\u003e\n \u003cp\u003eNone\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 85px;\"\u003e\n \u003cp\u003e46\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003e(95.8)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 85px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003e(0.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 104px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003e(4.2)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"4\" valign=\"top\" style=\"width: 85px;\"\u003e\n \u003cp\u003e28.1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"4\" valign=\"top\" style=\"width: 85px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u0026lt;0.001\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 76px;\"\u003e\n \u003cp\u003eMild\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 85px;\"\u003e\n \u003cp\u003e59\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003e(60.2)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 85px;\"\u003e\n \u003cp\u003e13\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003e(13.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 104px;\"\u003e\n \u003cp\u003e26\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003e(26.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 76px;\"\u003e\n \u003cp\u003eModerate\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 85px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003e(33.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 85px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003e(0.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 104px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003e(66.7)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 76px;\"\u003e\n \u003cp\u003eSevere\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 85px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003e(0.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 85px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003e(0.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 104px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003e(100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd rowspan=\"4\" valign=\"top\" style=\"width: 103px;\"\u003e\n \u003cp\u003eGlandular Atrophy\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 76px;\"\u003e\n \u003cp\u003eNone\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 85px;\"\u003e\n \u003cp\u003e41\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003e(67.2)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 85px;\"\u003e\n \u003cp\u003e5\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003e(8.2)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 104px;\"\u003e\n \u003cp\u003e15\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003e(24.6)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"4\" valign=\"top\" style=\"width: 85px;\"\u003e\n \u003cp\u003e17.1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"4\" valign=\"top\" style=\"width: 85px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e0.009\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 76px;\"\u003e\n \u003cp\u003eMild\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 85px;\"\u003e\n \u003cp\u003e60\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003e(75.9)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 85px;\"\u003e\n \u003cp\u003e4\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003e(5.1)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 104px;\"\u003e\n \u003cp\u003e15\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003e(19.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 76px;\"\u003e\n \u003cp\u003eModerate\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 85px;\"\u003e\n \u003cp\u003e4\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003e(44.4)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 85px;\"\u003e\n \u003cp\u003e4\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003e(44.4)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 104px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003e(11.1)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 76px;\"\u003e\n \u003cp\u003eSevere\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 85px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003e(100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 85px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003e(0.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 104px;\"\u003e\n \u003cp\u003e0\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003e(0.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd rowspan=\"2\" valign=\"top\" style=\"width: 103px;\"\u003e\n \u003cp\u003eIntestinal Metaplasia\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 76px;\"\u003e\n \u003cp\u003eNone\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 85px;\"\u003e\n \u003cp\u003e104\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003e(74.8)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 85px;\"\u003e\n \u003cp\u003e10\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003e(7.2)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 104px;\"\u003e\n \u003cp\u003e25\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003e(18.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" valign=\"top\" style=\"width: 85px;\"\u003e\n \u003cp\u003e16.0\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" valign=\"top\" style=\"width: 85px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u0026lt;0.001\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 76px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003eMild\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 85px;\"\u003e\n \u003cp\u003e2\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003e(18.2)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 85px;\"\u003e\n \u003cp\u003e3\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003e(27.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 104px;\"\u003e\n \u003cp\u003e6\u003c/p\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003cp\u003e(54.5)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp\u003e\u0026nbsp;\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eTable\u0026nbsp;\u003c/strong\u003e\u003cstrong\u003e4\u003c/strong\u003e\u003cstrong\u003e: The association between \u003cem\u003eH. pylori\u003c/em\u003e infection and age groups.\u003c/strong\u003e\u003c/p\u003e\n\u003ctable border=\"0\" cellspacing=\"0\" cellpadding=\"0\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd rowspan=\"2\" valign=\"top\" style=\"width: 109px;\"\u003e\n \u003cp\u003e\u003cem\u003eH. pylori\u003c/em\u003e infection\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"3\" valign=\"top\" style=\"width: 363px;\"\u003e\n \u003cp\u003eAge groups\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" valign=\"top\" style=\"width: 129px;\"\u003e\n \u003cp\u003eChi-square\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 103px;\"\u003e\n \u003cp\u003e5 \u0026ndash; 18 (n=5)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 119px;\"\u003e\n \u003cp\u003e19 \u0026ndash; 59 (n=112)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 142px;\"\u003e\n \u003cp\u003e\u0026ge; 60 (n=33 )\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 109px;\"\u003e\n \u003cp\u003ePresent\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 103px;\"\u003e\n \u003cp\u003e0 (0.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 119px;\"\u003e\n \u003cp\u003e39 (34.8%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 142px;\"\u003e\n \u003cp\u003e5 (15.2%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" valign=\"top\" style=\"width: 129px;\"\u003e\n \u003cp\u003e6.9\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 109px;\"\u003e\n \u003cp\u003eAbsent\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 103px;\"\u003e\n \u003cp\u003e5 (100.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 119px;\"\u003e\n \u003cp\u003e73 (65.2)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 142px;\"\u003e\n \u003cp\u003e28 (84.8%)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 109px;\"\u003e\n \u003cp\u003ep-Value\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"3\" valign=\"top\" style=\"width: 363px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e0.032\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 129px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp\u003e\u0026nbsp;\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eTable\u0026nbsp;\u003c/strong\u003e\u003cstrong\u003e5\u003c/strong\u003e\u003cstrong\u003e: The association between \u003cem\u003eH. pylori\u003c/em\u003e infection and sex.\u003c/strong\u003e\u003c/p\u003e\n\u003ctable border=\"0\" cellspacing=\"0\" cellpadding=\"0\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd rowspan=\"2\" valign=\"top\" style=\"width: 134px;\"\u003e\n \u003cp\u003e\u003cem\u003eH. pylori\u003c/em\u003e infection\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" valign=\"top\" style=\"width: 268px;\"\u003e\n \u003cp\u003eSex\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" valign=\"top\" style=\"width: 199px;\"\u003e\n \u003cp\u003eChi- Square\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 134px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eMale (n= 90)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 134px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eFemale (n=60 )\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 134px;\"\u003e\n \u003cp\u003ePresent\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 134px;\"\u003e\n \u003cp\u003e27 (30.0%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 134px;\"\u003e\n \u003cp\u003e16 (26.7%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd rowspan=\"2\" valign=\"top\" style=\"width: 199px;\"\u003e\n \u003cp\u003e0.067\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 134px;\"\u003e\n \u003cp\u003eAbsent\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 134px;\"\u003e\n \u003cp\u003e63 (70.0%)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 134px;\"\u003e\n \u003cp\u003e44 (73.3%)\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 134px;\"\u003e\n \u003cp\u003ep-Value\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd colspan=\"2\" valign=\"top\" style=\"width: 268px;\"\u003e\n \u003cp\u003e0.796\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 199px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e\n\u003cp\u003e\u003cstrong\u003e\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eTable\u0026nbsp;\u003c/strong\u003e\u003cstrong\u003e6\u003c/strong\u003e\u003cstrong\u003e: Bivariable analysis of factors associated with presence of \u003cem\u003eH. pylori\u003c/em\u003e infection density in chronic gastritis.\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003e\u0026nbsp;\u003cimg 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\" width=\"641\" height=\"723\"\u003e\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eTable\u0026nbsp;\u003c/strong\u003e\u003cstrong\u003e7\u003c/strong\u003e\u003cstrong\u003e: Multivariate analysis of factors associated with \u003cem\u003eH. Pylori\u003c/em\u003e infection density in Chronic gastritis\u003c/strong\u003e\u003c/p\u003e\n\u003ctable border=\"0\" cellspacing=\"0\" cellpadding=\"0\" width=\"652\"\u003e\n \u003ctbody\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 182px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eCharacteristics (%)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 148px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eCrude Odds ratio\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 216px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eAdjusted Odds ratio (95% CI)\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 106px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eP-value\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 182px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eAge\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 148px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 216px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 106px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 182px;\"\u003e\n \u003cp\u003e19-59 years (34.8)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 148px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 216px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 106px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 182px;\"\u003e\n \u003cp\u003e\u0026ge;60 years (15.2)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 148px;\"\u003e\n \u003cp\u003e0.33\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 216px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 106px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 182px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eSex\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 148px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 216px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 106px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 182px;\"\u003e\n \u003cp\u003eMale (60.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 148px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 216px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 106px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 182px;\"\u003e\n \u003cp\u003eFemale (40.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 148px;\"\u003e\n \u003cp\u003e0.8\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 216px;\"\u003e\n \u003cp\u003e0.4 (0.56-9.40)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 106px;\"\u003e\n \u003cp\u003e0.247\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 182px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eChronic inflammation\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 148px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 216px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 106px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 182px;\"\u003e\n \u003cp\u003eMild (26.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 148px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 216px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 106px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 182px;\"\u003e\n \u003cp\u003eModerate (55.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 148px;\"\u003e\n \u003cp\u003e9.8\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 216px;\"\u003e\n \u003cp\u003e2.5 (0.27-23.25)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 106px;\"\u003e\n \u003cp\u003e0.414\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 182px;\"\u003e\n \u003cp\u003eSevere (18.7)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 148px;\"\u003e\n \u003cp\u003e494\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 216px;\"\u003e\n \u003cp\u003e215 (14.45-3221.87)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 106px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u0026lt;0.001\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 182px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eNeutrophil activity\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 148px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 216px;\"\u003e\u003cbr\u003e\u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 106px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 182px;\"\u003e\n \u003cp\u003eNone (40.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 148px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 216px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 106px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 182px;\"\u003e\n \u003cp\u003eMild to severe (60.0)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 148px;\"\u003e\n \u003cp\u003e25.4\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 216px;\"\u003e\n \u003cp\u003e12.6 (1.87-84.35)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 106px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e0.009\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 182px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eGlandular atrophy\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 148px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 216px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 106px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 182px;\"\u003e\n \u003cp\u003eNone (67.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 148px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 216px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 106px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 182px;\"\u003e\n \u003cp\u003eMild to severe (32.7)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 148px;\"\u003e\n \u003cp\u003e4.5\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 216px;\"\u003e\n \u003cp\u003e0.96 (0.30-3.18)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 106px;\"\u003e\n \u003cp\u003e0.966\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 182px;\"\u003e\n \u003cp\u003e\u003cstrong\u003eIntestinal metaplasia\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 148px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 216px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 106px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 182px;\"\u003e\n \u003cp\u003eNone \u0026nbsp; \u0026nbsp; (92.7)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 148px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 216px;\"\u003e\n \u003cp\u003e1\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 106px;\"\u003e\n \u003cp\u003e\u0026nbsp;\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003ctr\u003e\n \u003ctd valign=\"top\" style=\"width: 182px;\"\u003e\n \u003cp\u003eMild (7.3)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 148px;\"\u003e\n \u003cp\u003e13.4\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 216px;\"\u003e\n \u003cp\u003e11.6 (1.05-126.69)\u003c/p\u003e\n \u003c/td\u003e\n \u003ctd valign=\"top\" style=\"width: 106px;\"\u003e\n \u003cp\u003e\u003cstrong\u003e0.045\u003c/strong\u003e\u003c/p\u003e\n \u003c/td\u003e\n \u003c/tr\u003e\n \u003c/tbody\u003e\n\u003c/table\u003e"}],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":true,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":false,"highlight":"","institution":"","isAcceptedByJournal":false,"isAuthorSuppliedPdf":false,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":false,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"gut-pathogens","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":false,"externalIdentity":"gutp","sideBox":"Learn more about [Gut Pathogens](http://gutpathogens.biomedcentral.com/)","snPcode":"13099","submissionUrl":"https://submission.nature.com/new-submission/13099/3","title":"Gut Pathogens","twitterHandle":"@GutPathogens","acdcEnabled":true,"dfaEnabled":true,"editorialSystem":"em","reportingPortfolio":"BMC/SO AJ","inReviewEnabled":true,"inReviewRevisionsEnabled":true},"keywords":"Helicobacter pylori, chronic gastritis, prevalence, histopathology, Uganda","lastPublishedDoi":"10.21203/rs.3.rs-7371222/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-7371222/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003e\u003cstrong\u003eBackground: \u003c/strong\u003eChronic gastritis is marked by persistent stomach mucosal inflammation due to a variety of etiologies but more commonly driven by \u003cem\u003eHelicobacter pylori\u003c/em\u003e (\u003cem\u003eH. pylori\u003c/em\u003e) infection, affecting over half the global population and increasing gastric cancer risk. This study investigated \u003cem\u003eH. pylori\u003c/em\u003e prevalence, its demographic and histopathological associations among chronic gastritis patients in Uganda.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eMethods: \u003c/strong\u003eA cross-sectional laboratory study analyzed 150 formalin-fixed paraffin-embedded tissue blocks from chronic gastritis patients using H\u0026amp;E and modified Giemsa stains. Data was analyzed with STATA version 17, determining prevalence through proportions, assessing associations using Chi-square tests and Fisher exact test, and conducting multivariate analysis with logistic regression. Significance was set at p≤0.05 with 95% confidence intervals.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eResults: \u003c/strong\u003eThe study included 150 patients (male-to-female ratio 1.5:1; mean age 48 years, SD=17, range 12–89). \u003cem\u003eH. pylori\u003c/em\u003e prevalence was 29.3%. Significant associations were observed with age (p=0.033), chronic inflammation (p=0.009), neutrophil activity (p\u0026lt;0.001), and intestinal metaplasia (p=0.045), but not sex (p=0.796). Multivariate analysis confirmed associations with severe chronic inflammation, neutrophil activity, and intestinal metaplasia, highlighting \u003cem\u003eH. pylori\u003c/em\u003e’s role in disease severity.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eConclusion: \u003c/strong\u003e\u003cem\u003eH. pylori\u003c/em\u003e infection, with a 29.3% prevalence, significantly contributes to chronic gastritis in Uganda. Its associations with age, chronic inflammation, neutrophil activity, and intestinal metaplasia emphasize the need for targeted eradication programs, particularly for adults, to prevent progression to severe gastric pathology, regardless of sex.\u003c/p\u003e","manuscriptTitle":"The Prevalence of Helicobacter Pylori Infection and the Associated Demographic and Histopathological Characteristics as seen in Patients Diagnosed with Chronic Gastritis in Uganda.","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2025-09-02 06:36:31","doi":"10.21203/rs.3.rs-7371222/v1","editorialEvents":[{"type":"communityComments","content":0},{"type":"decision","content":"Revision requested","date":"2025-10-21T01:24:32+00:00","index":"","fulltext":""},{"type":"editorInvitedReview","content":"","date":"2025-10-05T20:18:23+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"63500865893827993104346473456435028100","date":"2025-09-24T12:56:44+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"270146282083759482050895405869831892009","date":"2025-09-21T10:05:33+00:00","index":"hide","fulltext":""},{"type":"editorInvitedReview","content":"","date":"2025-09-20T18:27:29+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"155320004946047558556453371465696572321","date":"2025-09-19T09:16:14+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"76328131210433197357154686753956941005","date":"2025-09-19T08:58:01+00:00","index":"hide","fulltext":""},{"type":"editorInvitedReview","content":"","date":"2025-09-14T17:48:15+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"316370537195402553997544508473396936408","date":"2025-08-28T11:22:37+00:00","index":"hide","fulltext":""},{"type":"editorInvitedReview","content":"","date":"2025-08-25T16:36:32+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"85040216611215615703400585123771671064","date":"2025-08-25T14:44:00+00:00","index":"hide","fulltext":""},{"type":"reviewersInvited","content":"","date":"2025-08-25T02:42:39+00:00","index":"","fulltext":""},{"type":"editorAssigned","content":"","date":"2025-08-19T15:50:02+00:00","index":"","fulltext":""},{"type":"checksComplete","content":"","date":"2025-08-19T15:48:42+00:00","index":"","fulltext":""},{"type":"submitted","content":"Gut Pathogens","date":"2025-08-14T07:50:16+00:00","index":"","fulltext":""}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"gut-pathogens","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":false,"externalIdentity":"gutp","sideBox":"Learn more about [Gut Pathogens](http://gutpathogens.biomedcentral.com/)","snPcode":"13099","submissionUrl":"https://submission.nature.com/new-submission/13099/3","title":"Gut Pathogens","twitterHandle":"@GutPathogens","acdcEnabled":true,"dfaEnabled":true,"editorialSystem":"em","reportingPortfolio":"BMC/SO AJ","inReviewEnabled":true,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"281d2451-c791-4704-8720-75cdd1f83153","owner":[],"postedDate":"September 2nd, 2025","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"under-review","subjectAreas":[],"tags":[],"updatedAt":"2026-05-24T06:23:17+00:00","versionOfRecord":[],"versionCreatedAt":"2025-09-02 06:36:31","video":"","vorDoi":"","vorDoiUrl":"","workflowStages":[]},"version":"v1","identity":"rs-7371222","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-7371222","identity":"rs-7371222","version":["v1"]},"buildId":"8U1c8b4HqxoKbykW_rLl7","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}