The ability of phase angle to predict death risk factors in maintenance hemodialysis patients

Objectives: To investigate the ability of phase angle and body composition to predict the death risk factors of maintenance hemodialysis (MHD) patients. Methods: We studied the cause of death in 43 MHD patients treated at our hemodialysis center between January 2016 and December 2021 and compared them with the 71 patients who survived. Body composition was measured using direct segmental multi­frequency bioelectrical impedance to obtain phase angle, fat-free mass(FFM), extracellular water/total body water(ECW/TBW), and waist circumference (WC). Laboratory test data were collected. Phase angle cut-off value associated variables were calculated using ROC analysis. The ability of body composition variables to predict death risk factors in MHD patients was evaluated. Results: : The most common cause of death was cardiovascular disease. ROC curve analysis showed that the optimal cut-off values for phase angle as death risk factors in MHD patients was 4.50°. Moreover, in MHD patients, lower phase angle, aging and hypoproteinemia are death risk factors. Conclusion: Cardiovascular disease is the most common cause of death in MHD patients. Lower phase angle, aging, and hypoproteinemia can indicate risk of death in MHD patients. The potential mechanism of lower phase angle to predict the prognosis of MHD patients.