Case Report of a 47-Year-Old Long COVID Patient Diagnosed With Alzheimer's Disease

Abstract A 47-year-old female patient was diagnosed with Alzheimer disease (AD) based on positive Amyloid-PET and Tau-PET imaging results, coupled with increased levels of plasma biomarkers (Aβ42/Aβ40, pTau181, and pTau217). In this report, we characterized this unusual AD case by integrating data from various diagnostic methods, including PET, MRI imaging, genetic testing, plasma biomarker testing, etc, to contribute to future research and guide clinical practice. Given that this case emerged after the peak of the COVID-19 pandemic, we suggest that the AD cases analogous to this one be categorized under a distinct subset within the long COVID syndromes, termed AD-like COVID syndromes.