Ultrasound assessment of the endometric in postmenopausal asymptomatic women using hormonal substitutions

In: Geburtshilfe und Frauenheilkunde · 2022 · vol. 82(10) , pp. e56 · doi:10.1055/s-0042-1756775 · W4307688890
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AI-generated summary by claude@2026-06, 2026-06-10

This study aimed to use ultrasound to detect endometrial pathology in asymptomatic postmenopausal women undergoing hormone replacement therapy with Timbolone.

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AI-generated deep summary by claude@2026-06, 2026-06-10

This retrospective study evaluated endometrial thickness in 850 asymptomatic postmenopausal women (48–58 years; 2–3 years since menopause) undergoing annual preventive gynecologic examinations while using hormone substitutions, comparing Timbolone versus MF11RCE-yalouronic acid with transvaginal ultrasound. Endometrial thickness ≤6 mm was treated as normal, and women with thickness >6 mm were referred for diagnostic fractional abrasion combined with hysteroscopy. The authors reported that 33.6% had thickness <6 mm, 12.26% were between 5–7 mm, and 4.13% were ≥8 mm, and they found no statistically significant difference in thickness between the hormone groups. The study’s limitation is that it focused on thickness measurements and comparative ultrasound outcomes without providing detailed diagnostic pathology results in the provided text. Relevance to endometriosis: the paper is not centrally about endometriosis or adenomyosis; it was included in the corpus via a keyword match related to endometrial assessment in endometrial pathology risk contexts.

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Abstract

Aim The observed steady increase in morbidity, mortality and incidence of endometrial cancer has aroused the interest of many researchers to find methods for early diagnosis of endometrial neoplasms. The purpose of this study is the early detection of endometrial pathology in postmenopausal women (PMW) without clinical symptoms with hormone replacement therapy (Timbolone, MF11RCE-yalouronyc acid).

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