Roadmap on biomaterials for women’s health

Kaitlin C. Fogg, Ning-Hsuan Tseng, Shelly R. Peyton, Pieper Holeman, Shannon Mc Loughlin, John P. Fisher, Allison Sutton, Ariella Shikanov, Juan S. Gnecco, Katrina Knight, Emily M. Slaby, Jessica D. Weaver, Nicole N. Hashemi, Yali Zhang, Michael House, Brandon J. Vogt, Brian A. Aguado, John C Bradford, Jennifer L. Robinson, Patricia K. Thomas, Anthony G Lau, Michelle L. Oyen
In: Journal of Physics: Materials · 2022 · vol. 6(1) , pp. 012501 · doi:10.1088/2515-7639/ac90ee · PMID:42220979 · PMC13218746 · W4295132168
article OA: gold CC0 ⤵ 3 in-corpus citations
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

This roadmap reviews biomaterial applications for women's health, covering conditions unique to females, those disproportionately affecting them, and sex differences in non-reproductive tissues, for both in vivo and in vitro research.

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Abstract

Abstract The application of engineering tools and techniques to studying women’s health, including biomaterials-based approaches, is a research field experiencing robust growth. Biomaterials are natural or synthetic materials used to repair or replace damaged tissues or organs or replicate an organ’s physiological function. However, in addition to in vivo applications, there has been substantial recent interest in biomaterials for in vitro systems. Such artificial tissues and organs are employed in drug discovery, functional cell biological investigations, and basic research that would be ethically impossible to conduct in living women. This Roadmap is a collection of 11 sections written by leading and up-and-coming experts in this field who review and discuss four aspects of biomaterials for women’s health. These include conditions that disproportionately but not exclusively affect women (e.g. breast cancer), conditions unique to female reproductive organs, in both non-pregnant and pregnant states, and sex differences in non-reproductive tissues (e.g. the cardiovascular system). There is a strong need to develop this exciting field, with the potential to materially influence women’s lives worldwide.

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