Features of pathogenesis of combination of a genital endometriosis and hypothyrosis

B. M. Lysenko
In: HEALTH OF WOMAN · 2016 · pp. 75–77 · doi:10.15574/hw.2016.115.75 · W3113080029
article OA: diamond CC0 ⤵ 1 in-corpus citation
🔓 Open OA copy Full text JSON View on OpenAlex View at publisher
⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-11 ⓘ

This study investigated the pathogenesis of external genital endometriosis combined with hypothyroidism and found that hyperproduction of thyrotropic hormone decreases follicle-stimulating hormone and increases prolactin, impairing ovarian estrogen production.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

⚙ AI-generated deep summary by claude@2026-06, 2026-06-11 · read from full text ⓘ

The paper studied features of the pathogenesis of external genital endometriosis in relation to hypothyroidism, surveying 110 women of reproductive age (20–41 years) with external genital endometriosis divided into those without thyroid pathology (n=50) and those with accompanying hypothyroidism (n=60). The findings indicated an “essential role” of endocrinologic status, describing hypothyroidism-associated hyperproduction of thyrotropic hormone that was linked to decreased follicle-stimulating hormone, increased prolactin production, and suppression of ovarian estrogen-producing function. A stated limitation is that the work is based on patient survey/group comparison without more specific methodological detail in the abstract, and the conclusions are framed around pathogenesis considerations rather than mechanistic proof. This paper is centrally about endometriosis — specifically the pathogenesis of external genital endometriosis occurring in the setting of hypothyroidism.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Abstract

The objective: to establish features of pathogenesis of an external genital endometriosis against hypothyrosis. Patients and methods. For the solution of goal we surveyed 110 patients of genesial age from 20 to 41 year with an external genital endometriosis. All women were divided into two groups. The first group included 50 patients with an external genital endometriosis without pathology of thyroid gland, the second – 60 women with an external genital endometriosis and an accompanying hypothyrosis. Results. Results of the conducted researches testify to an essential role of the endocrinologic status in pathogenesis of an external genital endometriosis against hypothyrosis. The received results specify that the hyperproduction of thyritropic hormone at patients with an external genital endometriosis at hypofunction of thyroid gland promotes decrease of level of follicle-stimulating hormone and rising of production of prolactinum that leads to depression of estrogenprodutsiruyushchy function of ovaries. Conclusions. The received results need to be considered when developing tactics of maintaining these patients. Key words: external genital endometriosis, hypothyrosis, pathogenesis.
Full text 3,068 characters · extracted from oa-html · click to expand
- Features of pathogenesis of combination of a genital endometriosis and hypothyrosis Features of pathogenesis of combination of a genital endometriosis and hypothyrosis HEALTH OF WOMAN. 2016.9(115):75–77; doi 10.15574/HW.2016.115.75 Features of pathogenesis of combination of a genital endometriosis and hypothyrosis Lysenko B. M. National Medical Academy of Postgraduate Education P. L. Shupyk, Kiev The state administration Scientific-practical center of preventive and clinical medicine The objective: to establish features of pathogenesis of an external genital endometriosis against hypothyrosis. Patients and methods. For the solution of goal we surveyed 110 patients of genesial age from 20 to 41 year with an external genital endometriosis. All women were divided into two groups. The first group included 50 patients with an external genital endometriosis without pathology of thyroid gland, the second – 60 women with an external genital endometriosis and an accompanying hypothyrosis. Results. Results of the conducted researches testify to an essential role of the endocrinologic status in pathogenesis of an external genital endometriosis against hypothyrosis. The received results specify that the hyperproduction of thyritropic hormone at patients with an external genital endometriosis at hypofunction of thyroid gland promotes decrease of level of follicle-stimulating hormone and rising of production of prolactinum that leads to depression of estrogenprodutsiruyushchy function of ovaries. Conclusions. The received results need to be considered when developing tactics of maintaining these patients. Key words: external genital endometriosis, hypothyrosis, pathogenesis. REFERENCES 1. Abdullaeva UA, Ishchenko AI, Ozgen D. 2011. Topical issues of treatment of an external genital endometriosis with chronic pelvic pains. The Russian messenger of the obstetrician – gynecologist 1:41-45. 2. Adamyan LV, Bugrova EN, Mikoyan VD. 2012. Disturbance of an electron and transport chain as implication of an oksidativny stress at endometriosis. Problems of reproduction 5:103-107. 3. Adamyan LV, Kulakov VI, Andreyeva EN. 2009. Endometriosis: The management for doctors. M, Medicine:411. 4. Aylamazyan EK, Potin VV, Tarasova MA. 2011. Genital endometriosis. Gynecology from pubertate to postmenopause. M, Medical press inform:284-302. 5. Baskakov VP, Tsvelev YuV, Cyrus EF. 2012. Endometrioidny illness. SPb.: l:452. 6. Bravermann LI. 2010. Illnesses of thyroid gland. Under L.I. Braverman's edition (The translation from English). M, Medicine:377. 7. Galkina NV, Mazurin NV, Troshin EA. 2012. A diffuse euthyroid struma (epidemiology, an etiology and a pathogenesis, a role of genetic factors in development, treatment). Endocrinology Problems: 52;4:49-56. 8. Gataulina RG. 2011. A functional condition of a thyroid gland at patients with tumorous formations of the ovaries suffering from sterility. The Messenger of obstetrics and gynecology 2:38-40. 9. Gerasimov AM. 2007. The sterility reasons at external endometriosis. Problems reproduction 3:66-69.

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

⚙ Ask this paper AI returns verbatim quotes from the full text · source: oa-html ⓘ

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Condition tags

endometriosis

Citation neighborhood (sparse)

Too few in-corpus citations on either side for a chart; here are the lists.

Cited by (1)

Cited by (1)

Source provenance

openalex
last seen: 2026-06-04T00:00:01.174412+00:00
License: CC0 · commercial use OK