TreeN93: a non-parametric distance-based method for inferring viral transmission clusters

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Abstract

Summary Highly-used methods for identifying transmission clusters of rapidly-evolving pathogens from molecular data require a user-determined distance threshold. The choice of threshold is often motivated by epidemiological information known a priori, which may be unfeasible for epidemics without rich epidemiological information. TreeN93 is a fully non-parametric distance-based method for transmission cluster identification that scales polynomially. Availability and implementation TreeN93 is implemented in Python 3 and is freely available at https://github.com/niemasd/TreeN93/ . Contact [email protected]

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last seen: 2026-05-19T01:45:01.086888+00:00