Endometriosis-associated intestinal tumors: a new challenge in clinical practice

Marta Merayo Álvarez, Daniel Fernández Martínez, José Antonio Álvarez Pérez, Guillermo Mendoza Pacas, José Electo Granero Trancón, Luis Joaquín Flórez García
Revista espanola de enfermedades digestivas · 2021 · vol. 113(11) , pp. 801–802 · doi:10.17235/reed.2021.8140/2021 · PMID:34423648
Case report OA: closed public-domain-us
Full text JSON View on PubMed View at publisher
⚙ AI-generated summary by qwen3.7-flash, 2026-10-02 ⓘ

This case report describes a 66-year-old woman with an endometriosis-associated presacral tumor causing sigmoid stricture, presenting with melena and constipation.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

⚙ AI-generated deep summary by qwen3.7-flash, 2026-09-07 · read from full text ⓘ

This letter describes the case of a 66-year-old female presenting with headache, diaphoresis, constipation, and melena, who was found to have a presacral mass infiltrating the sigmoid colon. Diagnostic imaging and scintigraphy identified an extrinsic stricture while ruling out paraganglioma, leading to a surgical proposal. The authors cite several prior reports of malignant degeneration in rectal endometriosis, including adenocarcinoma and clear cell carcinoma, to highlight this as a rare but significant clinical challenge. This paper is centrally about endometriosis — specifically discussing the risk of malignant transformation within intestinal endometriotic lesions.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Abstract

A 66-year-old female consulted due to headache associated with diaphoresis, constipation, and melena. A urinalysis revealed elevated metanephrines, and colonoscopy identified an extrinsic sigmoid stricture. CT and MRI showed a presacral mass infiltrating the sigma. Scintigraphy and SPECT ruled out a diagnosis of paraganglioma. Based on these findings, the patient was proposed to undergo surgery.
Full text 4,609 characters · extracted from oa-doi-fallback · 2 sections · click to expand

Abstract

A 66-year-old female consulted due to headache associated with diaphoresis, constipation, and melena. A urinalysis revealed elevated metanephrines, and colonoscopy identified an extrinsic sigmoid stricture. CT and MRI showed a presacral mass infiltrating the sigma. Scintigraphy and SPECT ruled out a diagnosis of paraganglioma. Based on these findings, the patient was proposed to undergo surgery. New comment Comments No comments for this article

References

1. Hoang CD, Boettcher AK, Jessurun J, et al. An Unusual Rectosigmoid Mass: Endometrioid Adenocareinoma Arising in Colonic Endometriosis: Case Report and Literature Review. Am Surg 2005;71(8):694-7. 2. Li N, Zhou W, Zhao L, et al. Endometriosis-associated recto-sigmoid cancer: a case report. BMC Cancer 2018;18(1):905. DOI: 10.1186/s12885-018-4797-4 3. García-Marín JA, Pellicer-Franco EM, Soria-Aledo V, et al. Malignant degeneration of rectal endometriosis. Rev Esp Enferm Dig 2015;107(12):761-3. DOI: 10.17235/reed.2015.3648/2014 4. Okazawa Y, Takahashi R, Mizukoshi K, et al. A case of clear cell adenocarcinoma arising from endometriosis of the rectum treated by laparoscopic surgery. Int J Surg Case Rep 2014;5(12):979-83. DOI: 10.1016/j.ijscr.2014.10.034 5. Benoit L, Arnould L, Cheynel N, et al. Malignant extraovarian endometriosis: A review. Eur J Surg Oncol EJSO 2006;32(1):6-11. DOI: 10.1016/j.ejso.2005.08.011 Related articles Digestive Diseases Image Uncommon gastric hernia in a parastomal defect DOI: 10.17235/reed.2024.10747/2024 Letter Burkitt’s lymphoma in the adult as an unusual cause of large bowel obstruction DOI: 10.17235/reed.2022.9306/2022 Digestive Diseases Image Cyclic hematochezia in a young woman with appendiceal endometriosis DOI: 10.17235/reed.2022.9257/2022 Letter Large bowel obstruction secondary to a simple renal cyst: an exceptional complication DOI: 10.17235/reed.2022.8623/2022 Digestive Diseases Image DOI: 10.17235/reed.2021.8459/2021 Letter Ileal endometriosis in a patient with Crohn’s disease: a diagnostic challenge DOI: 10.17235/reed.2021.8187/2021 Letter Spontaneous intramural small-bowel hematoma: a cause of acute abdomen in anticoagulated patients DOI: 10.17235/reed.2021.7640/2020 Letter Appendicular invagination as a rare manifestation of endometriosis DOI: 10.17235/reed.2020.7002/2020 Digestive Diseases Image Waugh’s syndrome: a rare cause of bowel obstruction in adults DOI: 10.17235/reed.2020.6977/2020 Letter Laparoscopic management of a small bowel obstruction caused by an endometriotic focus DOI: 10.17235/reed.2019.6220/2019 Letter DOI: 10.17235/reed.2018.5732/2018 Letter to the Editor Bowel obstruction secondary to deep infiltrating endometriosis of the ileum DOI: 10.17235/reed.2018.5364/2017 Letter to the Editor Ileocecal endometriosis as an infrequent cause of intussusception DOI: 10.17235/reed.2017.5183/2017 Letter to the Editor Symptomatic retention of the Agile® patency capsule DOI: 10.17235/reed.2017.4691/2016 Letter to the Editor DOI: 10.17235/reed.2016.4393/2016 Digestive Diseases Image Gallstone ileus presenting as obstructive gangrenous appendicitis Original Small bowel obstruction due to laparoscopic barbed sutures: An unknown complication? DOI: 10.17235/reed.2015.3863/2015 Citation tools Merayo Álvarez M, Fernández Martínez D, Álvarez Pérez J, Mendoza Pacas G, Granero Trancón J, Flórez García L, et all. Endometriosis-associated intestinal tumors: a new challenge in clinical practice. 8140/2021 Download the citation for this article by clicking on one of the following citation managers: Metrics Publication history Received: 07/06/2021 Accepted: 03/07/2021 Online First: 23/08/2021 Published: 05/11/2021 Article revision time: 23 days Article Online First time: 77 days Article editing time: 151 days Share This article hasn't been rated yet. Reader rating: Valora este artículo: Submit a manuscript Journal info Articles Submit a manuscript Journal info Articles Submit a manuscript The Spanish Journal of Gastroenterology is the official organ of the Sociedad Española de Patología Digestiva, the Sociedad Española de Endoscopia Digestiva and the Asociación Española de Ecografía Digestiva Cookie policy Privacy Policy Legal Notice © Copyright 2026 y Creative Commons. The Spanish Journal of Gastroenterology

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

⚙ Ask this paper AI returns verbatim quotes from the full text · source: oa-doi-fallback ⓘ

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Condition tags

endometriosis

MeSH descriptors

Endometriosis Endometriosis Endometriosis Endometriosis Endometriosis Intestinal Neoplasms Intestinal Neoplasms Aged Aged Colon, Sigmoid Colon, Sigmoid Constipation Constipation Constriction, Pathologic Constriction, Pathologic Female Female Humans Humans

Citation neighborhood (no data yet)

We don't have any in-corpus citations linked to this paper yet. The paper's references may be in our DB but unresolved to ``paper_id`` (resolution happens at ingest when the cited DOI matches a row we already have). Run the cross-source citation reconcile pass to retry.

Source provenance

europepmc
last seen: 2026-10-24T06:12:55.650802+00:00
pubmed
last seen: 2026-10-08T21:32:14.907849+00:00
unpaywall
last seen: 2026-10-24T06:30:43.844863+00:00
License: public-domain-us · commercial use OK · attribution required
Courtesy of the U.S. National Library of Medicine