Persistent Müllerian Duct Syndrome in Miniature Schnauzer

Diana Alexandra Rios Castro, Carlos Alberto Carlos Alberto, Nicolas Enriquez Montenegro, Sofia Juliana Merchancano Bravo, José Mauricio Quintero P, Ruben Serna M, Alba Lucia Romero Rivas, Tatiana Gabriela Paz Calvache, Alexander Portillo Gomez, Angie Matabajoy Suarez
In: Revista MVZ Córdoba · 2026 · vol. 31(1) , pp. e3691 · doi:10.21897/rmvz.3691 · W7140198313
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⚙ AI-generated summary by claude@2026-08, 2026-08-02 ⓘ

Three male Miniature Schnauzers diagnosed with Persistent Müllerian Duct Syndrome also presented with intratubular seminoma or Sertoli cell tumors and cystic endometrial hyperplasia with pyometra.

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Abstract

Persistent Müllerian duct syndrome (PMDS) is a rare condition reported in domestic animals, but it is more commonly observed in Miniature Schnauzer dogs due to its inheritance as an autosomal recessive trait. This genetic condition allows male animals to develop anatomical segments of the female reproductive tract. In this study, three male Miniature Schnauzer dogs presented with acute abdominal pain, vomiting, and tenesmus and were admitted to the emergency service. Ultrasound evaluation and exploratory laparotomy revealed structures morphologically consistent with the uterus, uterine horns, testicular organs, and a mass, all tissues were subjected to histopathological and immunohistochemical evaluation. Based on clinical, macroscopic, and microscopic findings, PMDS was diagnosed. Additionally, intratubular seminoma was identified intra-abdominally in the first two cases, while a Sertoli cell tumor was found in the third dog. Cystic endometrial hyperplasia with concurrent pyometra was also observed in each case.

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last seen: 2026-06-04T00:00:01.174412+00:00
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