The impact of gut microbiota, inflammation and oxidative stress on endometriosis, pain, quality of life and condition of patients’ health

Anna Hanslik, Magdalena Mendak, Agata Białek, Monika Klimczak, Aleksandra Woskowska, Magdalena Domisiewicz
In: Quality in Sport · 2025 · vol. 43 , pp. 61444 · doi:10.12775/qs.2025.43.61444 · W4412186695
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This study investigates the roles of gut microbiota, inflammation, and oxidative stress in endometriosis, its associated pain, and the overall health and quality of life of affected patients.

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⚙ AI-generated deep summary by claude@2026-07, 2026-07-16 · read from full text ⓘ

This paper examines the role of gut microbiota, inflammation, and oxidative stress in endometriosis, focusing on how these factors relate to pain, quality of life, and patients’ health status. It presents endometriosis as a systemic inflammatory disease affecting 5–10% of reproductive-age women and notes that laparoscopy is still needed for diagnosis, contributing to underdiagnosis and undertreatment. A key emphasis is that gut microbiome alterations and related inflammatory and oxidative stress mechanisms are recent areas of investigation, though the provided text does not describe specific study design, participant data, measurements, or results. This paper is centrally about endometriosis — specifically, it frames gut microbiota, inflammation, and oxidative stress as linked to endometriosis-associated pain and quality of life.

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Abstract

Endometriosis is a chronic complex, systemic inflammatory disease which affects 5-10% of reproductive-age women. There is a need for a surgical laparoscopy to establish the correct diagnosis, which means that the disease is still underdiagnosed and leads to undertreated patients’ health condition. Scientists are trying to find other factors causing and exacerbating this disease. Some of them like gut microbiome, inflammation and oxidative stress associated with endometriosis are recent discoveries.
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The impact of gut microbiota, inflammation and oxidative stress on endometriosis, pain, quality of life and condition of patients’ health DOI: https://doi.org/10.12775/QS.2025.43.61444Keywords Endometriosis, Inflammation, Oxidative Stress, Microbiome, Gut microbiome, Microbiota, Gut Microbiota, chronic pelvic painAbstract Endometriosis is a chronic complex, systemic inflammatory disease which affects 5-10% of reproductive-age women. There is a need for a surgical laparoscopy to establish the correct diagnosis, which means that the disease is still underdiagnosed and leads to undertreated patients’ health condition. Scientists are trying to find other factors causing and exacerbating this disease. Some of them like gut microbiome, inflammation and oxidative stress associated with endometriosis are recent discoveries. References 1. Hugh S Taylor, Alexander M Kotlyar, Valerie A Flores; https:// pubmed.ncbi.nlm.nih.gov/33640070/; DOI: 10.1016/S0140-6736(21)00389-5 2. C a t h e r i n e A l l a i r e , M o h a m e d A B e d a i w y, P a u l J Yo n g ; h t t p s : / / pubmed.ncbi.nlm.nih.gov/36918177/; DOI: 10.1503/cmaj.220637 3. Gabriela Cano-Herrera, Sylvia Salmun Nehmad, Jimena Ruiz de Chávez Gascón, Amairani Méndez Vionet, Ximena A van Tienhoven, María Fernanda Osorio Martínez, Mauricio Muleiro Alvarez, Mariana Ximena Vasco Rivero, María Fernanda López Torres, María Jimena Barroso Valverde, Isabel Noemi Torres, Alexa Cruz Olascoaga, Maria Fernanda Bautista Gonzalez, José Antonio Sarkis Nehme, Ignacio Vélez Rodrígun, Eder Gabriel Rivera Rosas, Dante Carbajal Ocampo, Ramiro Cabrera Carranco; https://pubmed.ncbi.nlm.nih.gov/39062050/; DOI: 10.3390/ biomedicines12071476 4. Jim Manos; https://pubmed.ncbi.nlm.nih.gov/35393656/; DOI: 10.1111/apm.13225 5. Hanne Van Gestel, Celine Bafort, Christel Meuleman, Carla Tomassetti, Arne Vanhie; https://pubmed.ncbi.nlm.nih.gov/38943813/; DOI: 10.1016/j.rbmo.2024.103848 6. M a r i a A r i a d n a O c h o a B e r n a l , A s g e r a l l y T F a z l e a b a s ; h t t p s : / / pubmed.ncbi.nlm.nih.gov/38892003/; DOI: 10.3390/ijms25115815 7. Philippe R Koninckx, Rodrigo Fernandes, Anastasia Ussia, Larissa Schindler, Arnaud Wattiez, Shaima Al-Suwaidi, Bedayah Amro, Basma Al-Maamari, Zeinab Hakim, Muna Tahlak; https://pubmed.ncbi.nlm.nih.gov/34899597/; DOI: 10.3389/ fendo.2021.745548 8. Teresa Mira Gruber, Sylvia Mechsner; https://pubmed.ncbi.nlm.nih.gov/34205040/; DOI: 10.3390/cells10061381 9. K Matsuura, H Ohtake, H Katabuchi, H Okamura; https://pubmed.ncbi.nlm.nih.gov/ 10087424/; DOI: 10.1159/000052855 10. J e l i z a v e t a L a m c e v a , R o m a n s U l j a n o v s , I l z e S t r u m f a ; h t t p s : / / pubmed.ncbi.nlm.nih.gov/36901685/; DOI: 10.3390/ijms24054254 11. Teresa Mira Gruber, Sylvia Mechsner; https://pubmed.ncbi.nlm.nih.gov/34205040/; DOI: 10.3390/cells10061381 12. Sanjay K Agarwal, Charles Chapron, Linda C Giudice, Marc R Laufer, Nicholas Leyland, Stacey A Missmer, Sukhbir S Singh, Hugh S Taylor; https:// pubmed.ncbi.nlm.nih.gov/30625295/; DOI: 10.1016/j.ajog.2018.12.039 13. Edgardo Rolla; https://pubmed.ncbi.nlm.nih.gov/31069056/; DOI: 10.12688/ f1000research.14817.1 14. Hafiz Muhammad Arsalan, Hina Mumtaz, Antonio Simone Lagana; https:// pubmed.ncbi.nlm.nih.gov/40185537/; DOI: 10.1016/bs.acc.2025.01.004 15. Elma Pašalić, Murtaza M Tambuwala, Altijana Hromić-Jahjefendić; https:// pubmed.ncbi.nlm.nih.gov/37844487/; DOI: 10.1016/j.prp.2023.154847 16. Mauricio S Abrao, Marina Paula Andres, Charles E Miller, Julian A Gingold, Mariona Rius, Joao Siufi Neto, Francisco Carmona; https://pubmed.ncbi.nlm.nih.gov/ 34583009/; DOI: 10.1016/j.jmig.2021.09.709 17. Jörg Keckstein, Gernot Hudelist; https://pubmed.ncbi.nlm.nih.gov/33558167/; DOI: 10.1016/j.bpobgyn.2020.11.004 18. Giulia Bonavina, Hugh S Taylor; https://pubmed.ncbi.nlm.nih.gov/36387918/; DOI: 10.3389/fendo.2022.1020827 19. Patricia Ribeiro de Carvalho França, Anna Carolina Pereira Lontra, Patricia Dias Fernandes; https://pubmed.ncbi.nlm.nih.gov/35807280/; DOI: 10.3390/ molecules27134034 20. Matthew Latham Macer, Hugh S Taylor; https://pubmed.ncbi.nlm.nih.gov/23182559/; DOI: 10.1016/j.ogc.2012.10.002 21. Rui Qin, Gengren Tian, Junbao Liu, Lu Cao; https://pubmed.ncbi.nlm.nih.gov/ 36506023/; DOI: 10.3389/fcimb.2022.1069557 22. Anjeza Xholli, Francesca Cremonini, Isabella Perugi, Ambrogio Pietro Londero, Angelo Cagnacci; https://pubmed.ncbi.nlm.nih.gov/38139822/; DOI: 10.3390/ ph16121696 23. Shiwan Hu, Qiyou Ding, Wei Zhang, Mengjiao Kang, Jing Ma, Linhua Zhao; https:// pubmed.ncbi.nlm.nih.gov/37559394/; DOI: 10.1080/19490976.2023.2236749 24. Isabella Weber, Anna Sienko, Aleksandra Urban, Carolyn Szwed, Krzysztof Czajkowski, Pawel Basta, Jacek Sienko; https://pubmed.ncbi.nlm.nih.gov/37772919/; DOI: 10.5603/gpl.97581 25. Meng-Yao Wang, Li-Xuan Sang, Si-Yu Sun; https://pubmed.ncbi.nlm.nih.gov/ 38617735/; DOI: 10.3748/wjg.v30.i12.1655 26. Chandni Talwar, Vertika Singh, Ramakrishna Kommagani; https:// pubmed.ncbi.nlm.nih.gov/35878972/; DOI: 10.1093/biolre/ioac147 27. Gianluca Quaranta, Maurizio Sanguinetti, Luca Masucci; https:// pubmed.ncbi.nlm.nih.gov/31827467/; DOI: 10.3389/fimmu.2019.02653 28. Mary E Salliss, Leslie V Farland, Nichole D Mahnert, Melissa M Herbst-Kralovetz; https://pubmed.ncbi.nlm.nih.gov/34718567/; DOI: 10.1093/humupd/dmab035 29. Tamy Colonetti, Maria Carolina Saggioratto, Antonio José Grande, Laura Colonetti, João Carlos Denoni Junior, Luciane Bisognin Ceretta, Leonardo Roever, Fábio Rosa Silva, Maria Inês da Rosa; https://pubmed.ncbi.nlm.nih.gov/38601772/; DOI: 10.1155/2023/2675966 30. Philippe R Koninckx, Anastasia Ussia, Leila Adamyan, Arnaud Wattiez, Victor Gomel, Dan C Martin; https://pubmed.ncbi.nlm.nih.gov/30527836/; DOI: 10.1016/ j.fertnstert.2018.10.013 Downloads Published How to Cite Issue Section License Copyright (c) 2025 Anna Hanslik, Magdalena Mendak, Agata Białek, Monika Klimczak, Aleksandra Woskowska, Magdalena Domisiewicz This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License. Stats Number of views and downloads: 508 Number of citations: 0

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