Effect of nerve intervention combined with intravenous thrombolysis on the vascular recanalization rate in patients with acute ischemic stroke

Abstract Objective To investigate the effect of nerve intervention combined with intravenous thrombolysis on the rate of vascular revascularization in patients with acute ischemic stroke. Methods The clinical data of 118 patients with acute ischemic stroke admitted to our hospital from January 2020 to March 2021 were retrospectively analyzed, and the enrolled patients were divided into a control group and an observation group. The control group received intravenous thrombolysis, and the observation group received neurological intervention based on intravenous thrombolysis. The clinical efficacy and vascular recanalization were compared between two groups after six months of treatment. Results After six months of treatment, the total effective rate (94.92%, 56/59) and complete recurrence rate (62.71%, 37/59) in the observation group were significantly higher than in the control group. Before treatment, there were no significant differences between the two groups' peak systolic flow velocity and neurological loss (P > 0.05). After six months of treatment, the vertebral artery systolic peak flow velocity, basilar artery systolic peak flow velocity, and the total incidence of adverse reactions in the observation group were significantly lower than those in the control group (P < 0.05). Conclusion The therapeutic effect of nerve intervention on patients with acute ischemic stroke is superior to that of intravenous thrombolysis alone and can effectively improve the rate of vascular revascularization, promote cerebral blood circulation, and reduce the adverse reactions induced by intravenous thrombolysis. It is safe and worthy of clinical application in the future.