Research on the apoptosis and proliferation features in ectopic endometrial cells of uterus and ovary

Objective:To investigate the property of apoptosis and proliferation of the ectopic endometrial cells in adenonyosis and ovarian ectopic cyst as well as their possible pathogenesis.Methods:To detect the expression of the apoptotic protein Bcl-2,bax and the cell proliferating labeling antigen ki-67 in eutopic and ectopic endometrial cells of adenomyosis and ovarian ectopic cyst with the immunohistochemical s-p method.Results:Protein Bcl-2,bax and ki-67 cyclically changed both in the eutopic and the ectopic endometrial cells of adenomyosis and ovarian cyst; while protein Bcl-2,bax and ki-67 of ovarian ectopic cyst were continuously enhanced,which was significantly different from that of eutopic endometrium(P0.05).Conclusion:The apoptosis and proliferation of the ectopic endometrial cells in adenomyosis are cyclically adjusted by ovary,while those in ovarian ectopic cyst are contrary to them,either of which has its own origin.