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Addiction and the Brain | Authorea try { document.documentElement.classList.add('js'); } catch (e) { } var _gaq = _gaq || []; _gaq.push(['_setAccount', 'G-8VDV14Y67G']); _gaq.push(['_trackPageview']); (function() { var ga = document.createElement('script'); ga.type = 'text/javascript'; ga.async = true; ga.src = ('https:' == document.location.protocol ? 'https://ssl' : 'http://www') + '.google-analytics.com/ga.js'; var s = document.getElementsByTagName('script')[0]; s.parentNode.insertBefore(ga, s); })(); Skip to main content Preprints Collections Wiley Open Research IET Open Research Ecological Society of Japan All Collections About About Authorea FAQs Contact Us Quick Search anywhere Search for preprint articles, keywords, etc. Search Search ADVANCED SEARCH SCROLL This is a preprint and has not been peer reviewed. Data may be preliminary. 15 September 2025 V1 Latest version Share on Addiction and the Brain Author : Joe Ordia MD, FACS. 0000-0001-9799-8679 [email protected] Authors Info & Affiliations https://doi.org/10.22541/au.175795698.82600734/v1 154 views 94 downloads Contents Abstract Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract The staggering number of deaths from drug addiction, especially fentanyl is a matter of great concern for families, healthcare providers, regulatory agencies, and government leaders. Addiction is defined as a chronic brain disorder characterized by the compulsive urge to use a substance or engage in a behavior, even when it results in harmful consequences. The most severe manifestation of substance use disorder is substance addiction. Examples include alcohol, nicotine usually from cigarette smoking, and drugs such as opioids like morphine, heroine, and fentanyl. Behavioral addiction can involve gambling, and excessive social media use. A collective, comprehensive, and coordinated multi-strategy approach is required to effectively address the challenge. Information & Authors Information Version history V1 Version 1 15 September 2025 Copyright This work is licensed under a Non Exclusive No Reuse License. Keywords behavioral addiction craving depression dopamine drug addiction naloxone peer pressure social isolation substance use disorder Authors Affiliations Joe Ordia MD, FACS. 0000-0001-9799-8679 [email protected] View all articles by this author Metrics & Citations Metrics Article Usage 154 views 94 downloads .FvxKWukQNSOunydq8rnd { width: 100px; } Citations Download citation Joe Ordia MD, FACS.. Addiction and the Brain. Authorea . 15 September 2025. DOI: https://doi.org/10.22541/au.175795698.82600734/v1 If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your manager software from the list below and click Download. For more information or tips please see 'Downloading to a citation manager' in the Help menu . Format Please select one from the list RIS (ProCite, Reference Manager) EndNote BibTex Medlars RefWorks Direct import Tips for downloading citations document.getElementById('citMgrHelpLink').addEventListener('click', function() { popupHelp(this.href); return false; }); $(".js__slcInclude").on("change", function(e){ if ($(this).val() == 'refworks') $('#direct').prop("checked", false); $('#direct').prop("disabled", ($(this).val() == 'refworks')); }); View Options View options PDF View PDF Figures Tables Media Share Share Share article link Copy Link Copied! Copying failed. 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