[Vascular endothelial growth factor is up-regulated by leukemia inhibitory factor and interleukin-6 in human endometriotic stromal cells].

Yining Huang, Y Huang, Huang Y, C Zeng, Zeng C, Chuanli Zeng, Peng Wu, Wu PL, P L Wu, Y Zhou, Zhou Y, Yanan Zhou, Chuanhui Peng, C Peng, Peng C, Xue Q, Q Xue, Qing Xue, Y F Zhou, Yanfang Zhou, Zhou YF
Zhonghua fu chan ke za zhi · 2019 · vol. 54(5) , pp. 324–329 · doi:10.3760/cma.j.issn.0529-567x.2019.05.007 · PMID:31154714 · W2991651455
article OA: closed CC0 ⤵ 2 in-corpus citations
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-06-09 ⓘ

Leukemia inhibitory factor (LIF) and interleukin-6 (IL-6) were found to up-regulate vascular endothelial growth factor (VEGF) in human endometriotic stromal cells (ESCs), potentially promoting endometriosis.

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Abstract

Overexpression of LIF and IL-6 may synergistically contribute to upregulation of VEGF in ESC and promote development of endometriosis.

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Condition tags

endometriosis

MeSH descriptors

Endometriosis Interleukin-6 Leukemia Inhibitory Factor Stromal Cells Up-Regulation Vascular Endothelial Growth Factor A Cells, Cultured Endometriosis Endometriosis Endometrium Female Humans Interleukin-6 Polymerase Chain Reaction Stromal Cells Stromal Cells Up-Regulation Vascular Endothelial Growth Factors

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organisms 2
human human

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License: CC0 · commercial use OK