Outcomes from the surgical management of pilonidal sinus disease: a retrospective cohort study and literature review

Outcomes from the surgical management of pilonidal sinus disease: a retrospective cohort study and literature review | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article Outcomes from the surgical management of pilonidal sinus disease: a retrospective cohort study and literature review Peter Rogers, Vignesh Palanisamy, Justin Dourado, Zachary Delgado, and 3 more This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-7549654/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract Background: Pilonidal Sinus Disease is a challenging ailment that often requires surgical intervention for effective management. While the Karydakis is a well-tested approach to pilonidal sinus disease, the minimal tissue excision method has early evidence as a promising alternative in the treatment of pilonidal sinus disease. Our study aims to compare the minimal tissue excision method to the Karydakis procedure focusing on parameters such as final healing, initial healing, recurrence, time to healing, the number of subsequent operations, and time to recurrence. Methods: A total of 152 patients were included in this retrospective analysis, with 45 patients undergoing the minimal tissue excision procedure and 107 patients undergoing the Karydakis procedure for Pilonidal Sinus Disease. Data regarding the specified parameters were collected and statistically analyzed to assess the differences between the two surgical approaches. Results: Our analysis revealed no statistically significant differences between the minimal tissue excision and Karydakis techniques in terms of final healing (p = 0.779), initial healing (p = 0.436), recurrence post-healing (p = 0.242), the number of subsequent operations (p = 0.287), and time to recurrence (p = 1). However, a significant difference was observed in the time to healing, with the Karydakis method demonstrating a shorter median healing time (14.50 days) compared to the minimal tissue excision approach (68.00 days, p < 0.001). Conclusions: This comparative analysis suggests that both the minimal tissue excision and Karydakis surgical techniques yield comparable outcomes in the treatment of Pilonidal Sinus Disease concerning final healing, initial healing, recurrence, the number of subsequent operations, and time to recurrence. However, the Karydakis method stands out as it significantly shortens the time to healing, potentially offering a quicker recovery for patients. Full Text Additional Declarations No competing interests reported. Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-7549654","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":533450069,"identity":"c99b03f6-503f-4e74-9d31-17fe029b21cb","order_by":0,"name":"Peter 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While the Karydakis is a well-tested approach to pilonidal sinus disease, the minimal tissue excision method has early evidence as a promising alternative in the treatment of pilonidal sinus disease. Our study aims to compare the minimal tissue excision method to the Karydakis procedure focusing on parameters such as final healing, initial healing, recurrence, time to healing, the number of subsequent operations, and time to recurrence.\u0026nbsp;\u003c/p\u003e\n\u003cp\u003eMethods: A total of 152 patients were included in this retrospective analysis, with 45 patients undergoing the minimal tissue excision procedure and 107 patients undergoing the Karydakis procedure for Pilonidal Sinus Disease. Data regarding the specified parameters were collected and statistically analyzed to assess the differences between the two surgical approaches.\u0026nbsp;\u003c/p\u003e\n\u003cp\u003eResults: Our analysis revealed no statistically significant differences between the minimal tissue excision and Karydakis techniques in terms of final healing (p = 0.779), initial healing (p = 0.436), recurrence post-healing (p = 0.242), the number of subsequent operations (p = 0.287), and time to recurrence (p = 1). However, a significant difference was observed in the time to healing, with the Karydakis method demonstrating a shorter median healing time (14.50 days) compared to the minimal tissue excision approach (68.00 days, p \u0026lt; 0.001).\u0026nbsp;\u003c/p\u003e\n\u003cp\u003eConclusions: This comparative analysis suggests that both the minimal tissue excision and Karydakis surgical techniques yield comparable outcomes in the treatment of Pilonidal Sinus Disease concerning final healing, initial healing, recurrence, the number of subsequent operations, and time to recurrence. However, the Karydakis method stands out as it significantly shortens the time to healing, potentially offering a quicker recovery for patients.\u003c/p\u003e","manuscriptTitle":"Outcomes from the surgical management of pilonidal sinus disease: a retrospective cohort study and literature review","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2025-10-24 05:48:09","doi":"10.21203/rs.3.rs-7549654/v1","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"2e53e72e-22dd-426b-a0ef-3c8887c1a5b9","owner":[],"postedDate":"October 24th, 2025","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"posted","subjectAreas":[],"tags":[],"updatedAt":"2025-11-27T17:08:21+00:00","versionOfRecord":[],"versionCreatedAt":"2025-10-24 05:48:09","video":"","vorDoi":"","vorDoiUrl":"","workflowStages":[]},"version":"v1","identity":"rs-7549654","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-7549654","identity":"rs-7549654","version":["v1"]},"buildId":"8U1c8b4HqxoKbykW_rLl7","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}