Change of CA125 in nonmalingnant diseases

Objective: To study the change of CA125 in the nonmalignant diseases. Methods : The serum level of CA125 was assayed by using electrochemiluminescence immunoassay. Results: The serum level of CA125 was significanflyy elevated in benign diseases of patients of department of genecology compared with the control group, but was significantly decreased compared with patients with ovarian cancer( P 0. 01 ). The positive rate of adenomyosis was the highest ( 100% ). The positive rate of extrauterine pregnancy was the lowest(0% ). The serum level of CA125 was significantly el-evated in patients with benig diseases of lung compared with the control group( P 0. 01 ). The CA125 level in patients with pneumonia was significantly decreased compared with that of lung cancer and tuberculosis, incluaing pulmonary tuber-culosis and tuberculous pleurisy. Conclusion:The level of CA125 in the no.malignant diseases was increased.