Endometriosis and Infertility

Daniel Griffin
In: The Boston IVF Handbook of Infertility · 2017 · pp. 142–148 · doi:10.4324/9781351241496-13 · W2904441959
book-chapter OA: closed CC0 ⤵ 5 in-corpus citations
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⚙ AI-generated summary by claude@2026-07, 2026-07-11 ⓘ

This review describes endometriosis, its prevalence in infertile women, common symptoms, and recommends ovulation induction with clomiphene citrate and intrauterine insemination as the initial treatment for minimal/mild cases.

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Abstract

Endometriosis is defined as the presence of endometrial glands and stroma outside of the uterine cavity. One of the challenges practitioners face is how best to treat patients with endometriosis who have difficulties conceiving a pregnancy. Endometriosis is prevalent in women who have infertility. A patient history and physical examination can be useful in determining the probability of finding endometriosis. Common symptoms of endometriosis include dysmenorrhea, dyspareunia, pelvic pain, and infertility. In general, patients with minimal/mild endometriosis should be treated in a similar way to those with unexplained infertility. The combination of ovulation induction with intrauterine insemination (IUI) treatment is the best initial treatment. The usual starting medication is clomiphene citrate (CC) in combination with an IUI. In patients with endometriosis or unexplained infertility, treatment with CC and IUI up to four cycles should be offered initially.

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Condition tags

endometriosisdysmenorrheadyspareuniainfertility

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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