The levonorgestrel-releasing intrauterine system in modern gynaecology

C Jay McGavigan, Philip Owen
British journal of hospital medicine (London, England : 2005) · 2005 · doi:10.12968/hmed.2005.66.10.19896 · PMID:16255257
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⚙ AI-generated summary by claude@2026-06, 2026-06-13 ⓘ

The levonorgestrel-releasing intrauterine system, initially for contraception, is now used for gynecological conditions, with counseling mitigating side effects like breakthrough bleeding to improve compliance.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-13 · read from full text ⓘ

This article reviews the role of the levonorgestrel-releasing intrauterine system in modern gynecology, noting that although it was originally developed for contraception, it is now used for a range of gynaecological conditions. It highlights that compliance may be limited by bothersome side effects, especially breakthrough bleeding, which can lead to discontinuation. The main limitation is that the piece is a narrative review rather than an original study, and it does not provide specific comparative effectiveness data. Relevance to endometriosis: the paper is included in the corpus because it is about a gynaecologic therapy (the levonorgestrel-releasing intrauterine system) that is commonly discussed in relation to endometriosis management, though the provided text does not explicitly mention endometriosis.

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Abstract

The levonorgestrel-releasing intrauterine system was initially developed for contraception but is now widely used for a variety of gynaecological conditions. Compliance can sometimes be hampered by troublesome side effects (principally breakthrough bleeding) but appropriate counselling can reduce unnecessary discontinuation.
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British Journal of Hospital Medicine (BJHM) is published by IMR Press from Volume 87 Issue 1 (2026). Previous articles were published by another publisher under the hybrid model (CC-BY-NC license or on a subscription basis), and they are hosted by IMR Press on imrpress.com as a courtesy and upon agreement. The levonorgestrel-releasing intrauterine system in modern gynaecology C Jay McGavigan 1, Philip Owen 1 Affiliation Article Info 1 Department of Gynaecology, Glasgow Royal Infirmary, Glasgow G4 0SF Abstract The levonorgestrel-releasing intrauterine system was initially developed for contraception but is now widely used for a variety of gynaecological conditions. Compliance can sometimes be hampered by troublesome side effects (principally breakthrough bleeding) but appropriate counselling can reduce unnecessary discontinuation.

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Condition tags

endometriosis

MeSH descriptors

Contraceptive Agents, Female Intrauterine Devices, Medicated Levonorgestrel Contraceptive Agents, Female Contraceptive Agents, Female Endometriosis Endometriosis Female Hormone Replacement Therapy Hormone Replacement Therapy Humans Leiomyoma Leiomyoma Levonorgestrel Levonorgestrel Premenstrual Syndrome Premenstrual Syndrome Uterine Hemorrhage Uterine Hemorrhage Uterine Neoplasms

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Source provenance

europepmc
last seen: 2026-06-13T06:22:48.782012+00:00
pubmed
last seen: 2026-05-13T22:15:29.922408+00:00
unpaywall
last seen: 2026-05-14T19:30:52.867331+00:00
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