Endometrial Biopsy

Stephanie Long
In: Primary Care: Clinics in Office Practice · 2021 · vol. 48(4) , pp. 555–567 · doi:10.1016/j.pop.2021.07.003 · PMID:34752269 · W3214591018
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This paper describes the procedure and diagnostic utility of endometrial biopsies for evaluating uterine abnormalities and infertility in women.

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Abstract

Abnormal uterine bleeding is a frequent medical concern for premenopausal and postmenopausal patients. Endometrial biopsy is a safe, cost-effective option offered in the office setting. Although endometrial biopsy may result in insufficient tissue or false-negative results, data suggest that endometrial biopsy is 90% sensitive for endometrial cancer and 82% sensitive for atypical hyperplasia, with specificity of 100% for postmenopausal patients and similar results in premenopausal patients. Topical cervical analgesia and oral nonsteroidal anti-inflammatory drugs decrease a patient's discomfort during endometrial biopsy. Aftercare instructions and how patients want to receive results should be reviewed in advance of performing the endometrial biopsy.

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License: CC0 · commercial use OK