Fetal Sacrococcygeal Immature Teratoma: A Case Report and A Literature Review

Fetal Sacrococcygeal Immature Teratoma: A Case Report and A Literature Review | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Case Report Fetal Sacrococcygeal Immature Teratoma: A Case Report and A Literature Review Bao-qin Bai, Chun-hui Peng, yun zheng, juqin huang, Wei-hua Guo This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-6232097/v1 This work is licensed under a CC BY 4.0 License Status: Published Journal Publication published 17 Oct, 2025 Read the published version in BMC Pediatrics → Version 1 posted 9 You are reading this latest preprint version Abstract Background Fetal immature sacrococcygeal teratoma(SCT) is relatively rare. It is usually detected through prenatal color ultrasound examination during the middle or late stages of pregnancy. Diagnosis relies on histopathological examination. Surgical treatment includes tumor resection combined with partial resection of the sacrococcygeal bone. The prognosis of SCT after surgery is usually good. Neonatal deaths due to SCT are relatively rare. Currently, there are only a few related reports, and the cause of death is not completely clear. Further research is needed to explore this issue. Case presentation A 35-year-old pregnant woman at 33+1 weeks of gestation presented to the emergency department of our hospital with complaints of irregular abdominal pain and vaginal bleeding. An emergency cesarean section was performed via the lower uterine segment due to preterm labor, fetal distress, polyhydramnios, intensified abdominal pain, and vaginal bleeding. A female fetus was successfully delivered, and a large mass measuring 13x11x8 cm was identified in the sacrococcygeal region. The mass was found to be ruptured with active bleeding. A biopsy was performed at the rupture site for pathological examination, which confirmed the diagnosis of an immature SCT. Despite medical intervention, the newborn succumbed to irreversible heart failure and respiratory dysfunction on the 5th postpartum day. Conclusions We emphasizes the significance of prenatal abdominal color Doppler ultrasound examination in screening for SCT in newborns, and conducts an in-depth analysis of the related factors that may lead to the death of newborns due to SCT. Our report aims to enhance the understanding of clinical physicians regarding this disease, thereby optimizing the diagnosis and treatment strategies and further reducing the mortality rate. SCT Newborn Immature Cause of death Full Text Additional Declarations No competing interests reported. Supplementary Files Originaldata.xlsx Cite Share Download PDF Status: Published Journal Publication published 17 Oct, 2025 Read the published version in BMC Pediatrics → Version 1 posted Editorial decision: Revision requested 29 Apr, 2025 Reviews received at journal 16 Apr, 2025 Reviewers agreed at journal 03 Apr, 2025 Reviews received at journal 01 Apr, 2025 Reviewers agreed at journal 01 Apr, 2025 Reviewers invited by journal 01 Apr, 2025 Editor assigned by journal 27 Mar, 2025 Submission checks completed at journal 27 Mar, 2025 First submitted to journal 27 Mar, 2025 You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. 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Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-6232097","acceptedTermsAndConditions":true,"allowDirectSubmit":false,"archivedVersions":[],"articleType":"Case Report","associatedPublications":[],"authors":[{"id":444018736,"identity":"51473639-e6bc-4126-b67b-ab1236988069","order_by":0,"name":"Bao-qin 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It is usually detected through prenatal color ultrasound examination during the middle or late stages of pregnancy. Diagnosis relies on histopathological examination. Surgical treatment includes tumor resection combined with partial resection of the sacrococcygeal bone. The prognosis of SCT after surgery is usually good. Neonatal deaths due to SCT are relatively rare. Currently, there are only a few related reports, and the cause of death is not completely clear. Further research is needed to explore this issue.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eCase presentation\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eA 35-year-old pregnant woman at 33+1 weeks of gestation presented to the emergency department of our hospital with complaints of irregular abdominal pain and vaginal bleeding. An emergency cesarean section was performed via the lower uterine segment due to preterm labor, fetal distress, polyhydramnios, intensified abdominal pain, and vaginal bleeding. 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Our report aims to enhance the understanding of clinical physicians regarding this disease, thereby optimizing the diagnosis and treatment strategies and further reducing the mortality rate.\u003c/p\u003e","manuscriptTitle":"Fetal Sacrococcygeal Immature Teratoma: A Case Report and A Literature Review","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2025-04-21 17:22:14","doi":"10.21203/rs.3.rs-6232097/v1","editorialEvents":[{"type":"communityComments","content":0},{"type":"decision","content":"Revision requested","date":"2025-04-29T05:01:54+00:00","index":"","fulltext":""},{"type":"editorInvitedReview","content":"","date":"2025-04-16T19:28:58+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"15169922835383065062836417082664456933","date":"2025-04-03T15:29:27+00:00","index":"hide","fulltext":""},{"type":"editorInvitedReview","content":"","date":"2025-04-01T15:02:04+00:00","index":"hide","fulltext":""},{"type":"reviewerAgreed","content":"18462906576526063894233111628939783457","date":"2025-04-01T14:36:32+00:00","index":"hide","fulltext":""},{"type":"reviewersInvited","content":"","date":"2025-04-01T07:52:06+00:00","index":"","fulltext":""},{"type":"editorAssigned","content":"","date":"2025-03-27T06:44:21+00:00","index":"","fulltext":""},{"type":"checksComplete","content":"","date":"2025-03-27T06:17:58+00:00","index":"","fulltext":""},{"type":"submitted","content":"BMC Pediatrics","date":"2025-03-27T06:16:52+00:00","index":"","fulltext":""}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"bmc-pediatrics","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":false,"externalIdentity":"bped","sideBox":"Learn more about [BMC Pediatrics](http://bmcpediatr.biomedcentral.com/)","snPcode":"","submissionUrl":"https://www.editorialmanager.com/bped/default.aspx","title":"BMC Pediatrics","twitterHandle":"BMC_series","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"em","reportingPortfolio":"BMC Series","inReviewEnabled":true,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"a1b2a4a3-8c5f-4b12-8a01-ed7b52747e8b","owner":[],"postedDate":"April 21st, 2025","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"published-in-journal","subjectAreas":[],"tags":[],"updatedAt":"2025-10-20T16:09:54+00:00","versionOfRecord":{"articleIdentity":"rs-6232097","link":"https://doi.org/10.1186/s12887-025-06031-7","journal":{"identity":"bmc-pediatrics","isVorOnly":false,"title":"BMC Pediatrics"},"publishedOn":"2025-10-17 15:58:17","publishedOnDateReadable":"October 17th, 2025"},"versionCreatedAt":"2025-04-21 17:22:14","video":"","vorDoi":"10.1186/s12887-025-06031-7","vorDoiUrl":"https://doi.org/10.1186/s12887-025-06031-7","workflowStages":[]},"version":"v1","identity":"rs-6232097","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-6232097","identity":"rs-6232097","version":["v1"]},"buildId":"XKTyCvWXoU3ODBz1xrDgd","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}