Rare diagnosis: the second documented report of primary diffuse large B-cell lymphoma of the fallopian tube
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Abstract
Primary non-Hodgkin's lymphoma is a highly prevalent haematologic malignancy but contrarily, primary lymphoma of the female genital tract (PLFGT) is extremely rare. The most common histological subtype of PLFGT is diffuse large B-cell lymphoma (DLBCL), which most commonly arises from the ovary, cervix, uterus or vagina. It is rarer still for DLBCL to arise from the fallopian tube, and therefore, we present the second case ever reported. A woman in her 30s presented with abdominal pain and a pelvic mass on CT. The mass was laparoscopically excised, which allowed the histological diagnosis to be made, and the patient was subsequently treated with chemotherapy. This report aims to contribute to existing knowledge of this rare condition because, although unusual, PLFGT is a potential diagnosis to consider when managing pelvic masses.
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Abstract
Primary non-Hodgkin’s lymphoma is a highly prevalent haematologic malignancy but contrarily, primary lymphoma of the female genital tract (PLFGT) is extremely rare. The most common histological subtype of PLFGT is diffuse large B-cell lymphoma (DLBCL), which most commonly arises from the ovary, cervix, uterus or vagina. It is rarer still for DLBCL to arise from the fallopian tube, and therefore, we present the second case ever reported. A woman in her 30s presented with abdominal pain and a pelvic mass on CT. The mass was laparoscopically excised, which allowed the histological diagnosis to be made, and the patient was subsequently treated with chemotherapy. This report aims to contribute to existing knowledge of this rare condition because, although unusual, PLFGT is a potential diagnosis to consider when managing pelvic masses.
- Gynecological cancer
- Obstetrics and gynaecology
- Cancer - see Oncology
- Haematology (incl blood transfusion)
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Footnotes
Contributors The following author was responsible for drafting the text, sourcing and editing clinical images, investigating results, drawing original diagrams and algorithms, and critically revising important intellectual content: EJL. The following author gave final approval of the manuscript: SW. Guarantor: SW.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.
Competing interests None declared.
Provenance and peer review Not commissioned; externally peer reviewed.
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