Recent progress of Bioinspired Hydrogel-based delivery system for endometrial repair

Rong Dong, Saihua Ma, Xiaoli Zhao, Baojuan Wang, Mridul Roy, Yao Lü, Tian Xia, Yanting Liu
In: Frontiers in Bioengineering and Biotechnology · 2022 · vol. 10 , pp. 1013217 · doi:10.3389/fbioe.2022.1013217 · PMID:36159661 · W4295027482
review OA: gold CC0 ⤵ 1 in-corpus citation
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This review summarizes recent advancements in bioinspired hydrogel-based delivery systems for endometrial repair, highlighting their use as post-operative barriers and therapeutic delivery platforms.

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Abstract

Endometrial injury is the main fact leading to infertility. Current treatments of endometrial injury present many problems, such as unable to achieve desired effects due to low retention and the inherent potential risk of injury. Besides, it is important to the development of bioinspired material that can mimic the natural tissue and possess native tissue topography. Hydrogel is a kind of bioinspired superhydrophilic materials with unique characteristics, such as excellent biocompatibility, biodegradability, porosity, swelling, and cross-linkage. These unique physiochemical properties of bioinspired hydrogels enable their promising application as novel delivery platform and alternative therapies for endometrial injury. In this mini review, we summarize the recent advances in bioinispred hydrogel-based delivery system for endometrial repair, including as a post-operative physical barrier and therapeutic delivery system. In addition, present status, limitations, and future perspectives are also discussed.

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Condition tags

infertility

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Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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