Evaluation of Obstetric Outcomes in Women with Endometriosis

Ufuk Atlıhan, Ferruh Acet, Onur Yavuz, Burak Ersak, Can Ata, Tevfik Berk Bıldacı, Selçuk Erkılınç, Hüseyin Aytuğ AVŞAR
In: Türk Üreme Tıbbı ve Cerrahisi Dergisi · 2025 · vol. 9(1) , pp. 1–9 · doi:10.24074/tjrms.2024-105527 · W4409346709
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⚙ AI-generated summary by claude@2026-06, 2026-06-13 ⓘ

This study found that women with endometriosis had higher rates of ART use, gestational hypertension, cesarean delivery, blood loss, and NICU admission, along with earlier gestational age at birth.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-13 · read from full text ⓘ

This retrospective study evaluated obstetric and neonatal outcomes in 1015 women who had pregnancy follow-up and delivered in a single hospital from 2018–2023, comparing groups based on whether they had a diagnosis of endometriosis. Across the endometriosis group, the authors found higher rates of assisted reproductive technology use, gestational age was lower, and gestational hypertension, cesarean delivery, higher estimated blood loss, and higher NICU admission rates were all significantly more frequent. The study’s main caveat is that outcomes are observational and the authors conclude that perinatal risks are multifactorial, calling for prospective, large population-based studies or meta-analyses to clarify risks. This paper is centrally about endometriosis — it evaluates how endometriosis diagnosis is associated with obstetric and neonatal outcomes.

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Abstract

Objective: It is generally accepted that the endometrium of women with endometriosis is abnormal, although there is ongoing debate as to whether these abnormalities impair decidualization and placentation during pregnancy.The aim of this study is to evaluate the obstetric and neonatal outcomes in patients diagnosed with endometriosis.Material and Methods: 1015 patients who underwent pregnancy follow-up in our obstetrics clinic and gave birth in our hospital between 2018 and 2023 were retrospectively examined.The patients evaluated in the study were evaluated in two separate groups according to the presence of endometriosis.The presence of preterm delivery, gestational diabetes (GDM), gestational hypertension (GHT), preeclampsia, premature rupture of membranes (PROM), fetal growth restriction (FGR), Neonatal Intensive Care Unit (NICU) were evaluated in all patients.Results: ART presence was found to be significantly higher in the endometriosis group (p=0.038).Gestational week was found to be significantly lower in the endometriosis group (p=0.018).The GHT presence was found to be significantly higher in the endometriosis group (p=0.034).The Cesarean presence was found to be significantly higher in the endometriosis group (p=0.037).Estimated blood loss volume was significantly higher in the endometriosis group (p=0.042).The NICU rate was significantly higher in the endometriosis group (p=0.044).Conclusion: Perinatal and neonatal outcomes resulting from endometriosis depend on multifactorial factors.Prospective and large population-based studies or meta-analyses are needed to clarify possible risks.
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Abstract

Objective It is generally accepted that the endometrium of women with endometriosis is abnormal, although there is ongoing debate as to whether these abnormalities impair decidualization and placentation during pregnancy. The aim of this study is to evaluate the obstetric and neonatal outcomes in patients diagnosed with endometriosis.

Material and methods

1015 patients who underwent pregnancy follow-up in our obstetrics clinic and gave birth in our hospital between 2018 and 2023 were retrospectively examined. The patients evaluated in the study were evaluated in two separate groups according to the presence of endometriosis. The presence of preterm delivery, gestational diabetes (GDM), gestational hypertension (GHT), preeclampsia, premature rupture of membranes (PROM), fetal growth restriction (FGR), Neonatal Intensive Care Unit (NICU) were evaluated in all patients.

Results

ART presence was found to be significantly higher in the endometriosis group (p=0.038). Gestational week was found to be significantly lower in the endometriosis group (p=0.018).The GHT presence was found to be significantly higher in the endometriosis group (p=0.034). The Cesarean presence was found to be significantly higher in the endometriosis group (p=0.037). Estimated blood loss volume was significantly higher in the endometriosis group (p=0.042). The NICU rate was significantly higher in the endometriosis group (p=0.044).

Conclusion

Perinatal and neonatal outcomes resulting from endometriosis depend on multifactorial factors. Prospective and large population-based studies or meta-analyses are needed to clarify possible risks.

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endometriosis

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