Esketamine in the treatment of chronic endometriosis-induced pain: a case report
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An 8-hour esketamine infusion provided 8 weeks of pain relief for a patient with chronic endometriosis-induced pain resistant to conventional therapy.
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Abstract
Introduction: The pathophysiology of endometriosis-induced pain is complex and current pain management is often inadequate. As a consequence, the quality of life of endometriosis patients is reduced due to persistent and often recurrent severe pain, affecting emotional well-being. Case description: In this case report, we present a 28-year-old patient with deep endometriosis and severe pain resistant to conventional therapy, who experienced, after an 8-h infusion with esketamine, no pain symptoms for 8 weeks. Discussion: Current treatment options to suppress chronic pain symptoms in patients with (deep) endometriosis are often inadequate. Esketamine targets key components of the condition (inflammation, pain, depression), but the use of this drug in the treatment of chronic pain due to endometriosis has not been reported yet. Future trials are necessary to assess the effect of esketamine in the treatment of chronic pain due to endometriosis. Conclusion: This case report highlights the potential of esketamine infusion therapy in the treatment of endometriosis patients with persistent pain despite conventional therapy.
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Cites (2)
- Risk of Developing Comorbidities Among Women with Endometriosis: A Retrospective Matched Cohort Study 2018
- Chronic opioid use and complication risks in women with endometriosis: A cohort study in <scp>US</scp> administrative claims 2021
Cited by (4)
- Esketamine infusion therapy: A promising alternative in the treatment of chronic endometriosis-associated pain 2024
- Multiple drugs 2024
- Esketamine infusion as treatment for chronic endometriosis-associated pain? Study protocol for a randomized controlled trial (EASYlight-study) 2024
- Exploring Patient Adherence to Post-Surgical Follow-Up in Pelvic Endometriosis 2023
References (8)
- Chronic opioid use and complication risks in women with endometriosis: A cohort study in <scp>US</scp> administrative claims via openalex
- Risk of Developing Comorbidities Among Women with Endometriosis: A Retrospective Matched Cohort Study via openalex
- W2811304329 via openalex
- W3092324413 via openalex
- W4214754424 via openalex
- W1953082779 via openalex
- W4234160457 via openalex
- W2045893995 via openalex
Cited by (4)
- Esketamine infusion therapy: A promising alternative in the treatment of chronic endometriosis-associated pain 2024
- Multiple drugs 2024
- Esketamine infusion as treatment for chronic endometriosis-associated pain? Study protocol for a randomized controlled trial (EASYlight-study) 2024
- Exploring Patient Adherence to Post-Surgical Follow-Up in Pelvic Endometriosis 2023
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- last seen: 2026-06-10T17:14:06.276822+00:00
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