Determinants of Mother to Child Transmission of HIV In Public Hospitals of West Shewa Zone, Oromiya Region: mixed method study.

Determinants of Mother to Child Transmission of HIV In Public Hospitals of West Shewa Zone, Oromiya Region: mixed method study. | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Determinants of Mother to Child Transmission of HIV In Public Hospitals of West Shewa Zone, Oromiya Region: mixed method study. Fufa Hunduma Banja, Ewnat Gebrehanna This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-16716/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract Background: Mother-to-child transmission of HIV (MTCT) is when Human Immune deficiency Virus (HIV) of positive mother passes the virus to her baby. Without intervention transmission rate of HIV ranges from 15% to 45%, which can be reduced to below 5% with effective intervention. In Ethiopia, final mother-to-child transmission rate was 15% in 2016 which is much higher than target of the country to reduce transmission to lower than 5% by 2020. Aim of the study is to identify determinants of transmission of HIV from mother to child in West Shoa zone of Oromiya Region which has total population more than 2.1 million. Methods: Mixed methods: unmatched case-control study among children tested HIV positive and negatives at the end of PMTC follow up; N=96(24 cases, 72 controls) and one-on-one questioner for mothers of positive infant conducted during June to August 2019; focusing on PCR done during the last two years (June 2017 to July 2019), in public hospitals. Variables of interest were collected using structured and semi-structured questioner and data abstraction forms from mothers of exposed infants, medical records of mothers and children. Result: Majority among cases(70.8%) were not included in to option B+ program. Home delivery increases 6 times chance of HIV, AOR = 6.0; CI (1.5–29.2), none inclusion in to option B+ increase 18 chance of HIV transmission, AOR = 18.0; CI (5.0–68.1). Partner noninvolvement to HIV care increases chance of transmission by 7.3 times, AOR=7.3; CI(1.1–37.4). Mother-to- mother support program decrease chance of transmission by 86.5% with AOR = 0.13; CI (0.11–0.39). Poor ANC knowledge and practices among rural residents and unstable marriage in urban residents contributed to unaware MTCT of HIV. Conclusion: ART clinics should focus on and strengthen mother-to-mother support program, should create space for partner involvement to HIV care and provide training for Health Extension Workers(HEW). Health education and awareness creation should be implemented by HEW to improve ANC practice, reduce home delivery and increase voluntary counseling and testing among residents. Health Economics & Outcomes Research Health Policy Infectious Diseases PMTCT West Shewa HIV transmission Figures Figure 1 Figure 2 Figure 3 Full Text Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. 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Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-16716","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Research","associatedPublications":[],"authors":[{"id":397283,"identity":"a873f4df-0d78-4500-831e-3a6898d5ba70","order_by":1,"name":"Fufa Hunduma 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","lastPublishedDoi":"10.21203/rs.3.rs-16716/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-16716/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003e\u003cstrong\u003eBackground: \u003c/strong\u003eMother-to-child transmission of HIV (MTCT) is when Human Immune deficiency Virus (HIV) of positive mother passes the virus to her baby. Without intervention transmission rate of HIV ranges from 15% to 45%, which can be reduced to below 5% with effective intervention. In Ethiopia, final mother-to-child transmission rate was 15% in 2016 which is much higher than target of the country to reduce transmission to lower than 5% by 2020. Aim of the study is to identify determinants of transmission of\u0026nbsp;HIV from mother to child in West Shoa zone of Oromiya Region which has total population more than 2.1 million.\u003c/p\u003e\u003cp\u003e\u003cstrong\u003eMethods:\u003c/strong\u003e Mixed methods: unmatched case-control study among children tested HIV positive and negatives at the end of PMTC follow up; N=96(24 cases, 72 controls) and one-on-one questioner for mothers of positive infant conducted during June to August 2019; focusing on PCR done during the last two years (June 2017 to July 2019), in public hospitals. Variables of interest were collected using structured and semi-structured questioner and data abstraction forms from mothers of exposed infants, medical records of mothers and children.\u003c/p\u003e\u003cp\u003e\u003cstrong\u003eResult: \u003c/strong\u003eMajority among cases(70.8%) were not included in to option B+ program. Home delivery increases 6 times chance of HIV, AOR = 6.0; CI (1.5–29.2), none inclusion in to option B+ increase 18 chance of\u0026nbsp;HIV transmission, AOR = 18.0; CI (5.0–68.1). Partner noninvolvement to HIV care increases chance of transmission by 7.3 times, AOR=7.3; CI(1.1–37.4). Mother-to- mother support program decrease chance of transmission by 86.5% with AOR = 0.13; CI (0.11–0.39). Poor ANC knowledge and practices among rural residents and unstable marriage in urban residents contributed to unaware MTCT of HIV.\u003c/p\u003e\u003cp\u003e\u003cstrong\u003eConclusion:\u003c/strong\u003e ART clinics should focus on and strengthen mother-to-mother support program, should create space for partner involvement to HIV care and provide training for Health Extension Workers(HEW). Health education and awareness creation should be implemented by HEW to improve ANC practice, reduce home delivery and increase voluntary counseling and testing among residents.\u003c/p\u003e","manuscriptTitle":"Determinants of Mother to Child Transmission of HIV In Public Hospitals of West Shewa Zone, Oromiya Region: mixed method study.","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2020-03-11 14:50:50","doi":"10.21203/rs.3.rs-16716/v1","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"f0c7d4cf-fb46-450e-bd42-e91c93ac8bee","owner":[],"postedDate":"March 11th, 2020","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"posted","subjectAreas":[{"id":68492,"name":"Health Economics \u0026 Outcomes Research"},{"id":68493,"name":"Health Policy"},{"id":68494,"name":"Infectious Diseases"}],"tags":[],"updatedAt":"2020-09-08T13:03:47+00:00","versionOfRecord":[],"versionCreatedAt":"2020-03-11 14:50:50","video":"","vorDoi":"","vorDoiUrl":"","workflowStages":[]},"version":"v1","identity":"rs-16716","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-16716","identity":"rs-16716","version":["v1"]},"buildId":"WrCJVZZCHTDjtuVLN7oU0","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}