Detection of Nipah virus in human milk: a novel finding

Detection of Nipah virus in human milk: a novel finding | Authorea try { document.documentElement.classList.add('js'); } catch (e) { } var _gaq = _gaq || []; _gaq.push(['_setAccount', 'G-8VDV14Y67G']); _gaq.push(['_trackPageview']); (function() { var ga = document.createElement('script'); ga.type = 'text/javascript'; ga.async = true; ga.src = ('https:' == document.location.protocol ? 'https://ssl' : 'http://www') + '.google-analytics.com/ga.js'; var s = document.getElementsByTagName('script')[0]; s.parentNode.insertBefore(ga, s); })(); Skip to main content Preprints Collections Wiley Open Research IET Open Research Ecological Society of Japan All Collections About About Authorea FAQs Contact Us Quick Search anywhere Search for preprint articles, keywords, etc. Search Search ADVANCED SEARCH SCROLL Journal of Medical Virology This is a preprint and has not been peer reviewed. Data may be preliminary. 6 March 2025 V1 Latest version Share on Detection of Nipah virus in human milk: a novel finding Authors : Dewan Imtiaz Rahman 0009-0006-2337-6766 , Immamul Muntasir 0009-0004-3492-8680 , Md. Zulqarnine Ibne Noman 0000-0002-3720-3974 , Md. Jahidur Rahman , Md.Foyjul Islam 0000-0001-6601-5772 , Fateha Akhter Ema , Rashedul Alam Emon 0000-0001-9625-6307 , … Show All … , Monjurul Islam , Ahmad Raihan Sharif , Wasik Rahman Aquib , Ayesha Siddika , Md. Mahfuzur Rahman , Nisharggo Niloy , Arifa Nazneen , Mohammad Rashedul Hassan , Md. Omar Qayum , Mohammad Enayet Hossain 0000-0001-5511-1857 , Kamal Ibne Amin Chowdhury 0000-0001-7125-7071 , Ariful Islam , Mahbubur Rahman 0000-0001-8577-8281 , Sultana Sharmin , John Klena , Mohammed Ziaur Rahman 0000-0002-4103-4835 , Sayera Banu , Jonathan H. Epstein , Joel Montgomery , Tahmina Shirin 0000-0002-5061-3783 , and Syed Satter 0000-0002-2959-4522 [email protected] Show Fewer Authors Info & Affiliations https://doi.org/10.22541/au.174123366.63781482/v1 Published Journal of Medical Virology Version of record Peer review timeline 629 views 244 downloads Contents Abstract Supplementary Material Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract Background. Nipah virus (NiV) causes severe diseases in humans with a high case fatality rate. The primary risk factors for NiV infection in Bangladesh are drinking raw date palm sap (DPS) contaminated with Pteropus fruit bat secretions/excretions or close contact with or exposure to the body fluid of an individual with NiV infection. Methods. During the 2023 NiV outbreak investigation in Bangladesh, the breast milk of a NiV-infected nursing mother was tested by real-time reverse transcriptase polymerase chain reaction (RT-PCR) for detection of NiV-RNA. The newborn was also tested as a suspected NiV-infected subject. Results. NiV, specifically NiV RNA, was detected in the breast milk sample. Through the investigation, it was determined that the mother consumed raw DPS nine days before the delivery. The newborn was also confirmed as NiV positive and had exposure to maternal bodily fluid during delivery, while breastfeeding, and was in prolonged maternal contact during caregiving. Conclusion. By revealing breast milk as a potential source for NiV transmissions, our findings advocate for incorporating breast milk testing into NiV diagnostic protocols for symptomatic mothers. This advancement will broaden our understanding of mother-to-child NiV transmission and pave the way for more effective containment strategies. Supplementary Material File (detection of nipah virus in human milk a novel finding_manuscript_ v1.docx) Download 806.33 KB Information & Authors Information Version history V1 Version 1 06 March 2025 Peer review timeline Published Journal of Medical Virology Version of Record 30 Jun 2025 Published Copyright This work is licensed under a Non Exclusive No Reuse License. Collection Journal of Medical Virology Keywords epidemiology nipah virus pandemics paramyxovirus vertical transmission virus classification Authors Affiliations Dewan Imtiaz Rahman 0009-0006-2337-6766 International Centre for Diarrhoeal Disease Research Bangladesh View all articles by this author Immamul Muntasir 0009-0004-3492-8680 Institute of Epidemiology Disease Control and Research View all articles by this author Md. Zulqarnine Ibne Noman 0000-0002-3720-3974 International Centre for Diarrhoeal Disease Research Bangladesh View all articles by this author Md. Jahidur Rahman Institute of Epidemiology Disease Control and Research View all articles by this author Md.Foyjul Islam 0000-0001-6601-5772 Institute of Epidemiology Disease Control and Research View all articles by this author Fateha Akhter Ema International Centre for Diarrhoeal Disease Research Bangladesh View all articles by this author Rashedul Alam Emon 0000-0001-9625-6307 International Centre for Diarrhoeal Disease Research Bangladesh View all articles by this author Monjurul Islam Institute of Epidemiology Disease Control and Research View all articles by this author Ahmad Raihan Sharif Institute of Epidemiology Disease Control and Research View all articles by this author Wasik Rahman Aquib International Centre for Diarrhoeal Disease Research Bangladesh View all articles by this author Ayesha Siddika International Centre for Diarrhoeal Disease Research Bangladesh View all articles by this author Md. Mahfuzur Rahman International Centre for Diarrhoeal Disease Research Bangladesh View all articles by this author Nisharggo Niloy International Centre for Diarrhoeal Disease Research Bangladesh View all articles by this author Arifa Nazneen International Centre for Diarrhoeal Disease Research Bangladesh View all articles by this author Mohammad Rashedul Hassan Institute of Epidemiology Disease Control and Research View all articles by this author Md. Omar Qayum Institute of Epidemiology Disease Control and Research View all articles by this author Mohammad Enayet Hossain 0000-0001-5511-1857 International Centre for Diarrhoeal Disease Research Bangladesh View all articles by this author Kamal Ibne Amin Chowdhury 0000-0001-7125-7071 International Centre for Diarrhoeal Disease Research Bangladesh View all articles by this author Ariful Islam Charles Sturt University - Wagga Wagga Campus View all articles by this author Mahbubur Rahman 0000-0001-8577-8281 Institute of Epidemiology Disease Control and Research View all articles by this author Sultana Sharmin Institute of Epidemiology Disease Control and Research View all articles by this author John Klena Centers for Disease Control and Prevention Division of High Consequence Pathogens and Pathology View all articles by this author Mohammed Ziaur Rahman 0000-0002-4103-4835 International Centre for Diarrhoeal Disease Research Bangladesh View all articles by this author Sayera Banu International Centre for Diarrhoeal Disease Research Bangladesh View all articles by this author Jonathan H. Epstein One Health Science View all articles by this author Joel Montgomery Centers for Disease Control and Prevention Division of High Consequence Pathogens and Pathology View all articles by this author Tahmina Shirin 0000-0002-5061-3783 Institute of Epidemiology Disease Control and Research View all articles by this author Syed Satter 0000-0002-2959-4522 [email protected] International Centre for Diarrhoeal Disease Research Bangladesh View all articles by this author Metrics & Citations Metrics Article Usage 629 views 244 downloads .FvxKWukQNSOunydq8rnd { width: 100px; } Citations Download citation Dewan Imtiaz Rahman, Immamul Muntasir, Md. Zulqarnine Ibne Noman, et al. Detection of Nipah virus in human milk: a novel finding. Authorea . 06 March 2025. DOI: https://doi.org/10.22541/au.174123366.63781482/v1 If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. 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