Surgical Treatment of Madelung Deformity in Pediatric Patients: A Case Series

preprint OA: closed
Full text JSON View at publisher

Abstract

Abstract Background: Madelung deformity is a rare congenital wrist condition characterized by premature growth arrest of the distal radial physis, leading to wrist deformity and functional limitations. This study aimed to assess short-term functional and radiological outcomes in patients with Madelung deformity treated surgically at two Moroccan hospitals. Methods: This retrospective study included five skeletally immature patients (seven wrists) who underwent surgical treatment for Madelung deformity between January 2014 and July 2024. Patients underwent distal radial dome osteotomy, often combined with ulnar shortening osteotomy and Vickers ligament release. Outcomes were assessed using the Patient-Rated Wrist Evaluation, Visual Analog Scale for pain and satisfaction, range of motion measurements, and radiographic parameters. Results: The mean follow-up was 38.5 months. Postoperatively, improvements were observed in most range of motion parameters, particularly extension. The mean PRWE score improved, and patients reported high satisfaction with aesthetic outcomes. Radiographic parameters showed substantial corrections in ulnar tilt, lunate fossa angle, lunate subsidence, and palmar carpal displacement. Two wrists required reoperation due to complications or insufficient correction. Siblings with Léri-Weill syndrome demonstrated contrasting outcomes based on the timing of intervention and initial deformity severity. Conclusion: Combined radial and ulnar osteotomies improved pain, function, and radiographic parameters in adolescents with symptomatic Madelung deformity in the short to medium term. Early diagnosis and intervention may lead to better outcomes. Larger, prospective studies with longer follow-up are needed to establish optimal treatment algorithms and long-term outcomes. Level of Evidence Therapeutic Level IV. This was a retrospective case series.
Full text 13,820 characters · extracted from preprint-html · click to expand
Surgical Treatment of Madelung Deformity in Pediatric Patients: A Case Series | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article Surgical Treatment of Madelung Deformity in Pediatric Patients: A Case Series Soufiane Essamoud, Mohamed Lahlou, Achraf Benmazhar, Rania Bennani, and 3 more This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-7077906/v1 This work is licensed under a CC BY 4.0 License Status: Published Journal Publication published 18 Nov, 2025 Read the published version in Cureus → Version 1 posted You are reading this latest preprint version Abstract Background: Madelung deformity is a rare congenital wrist condition characterized by premature growth arrest of the distal radial physis, leading to wrist deformity and functional limitations. This study aimed to assess short-term functional and radiological outcomes in patients with Madelung deformity treated surgically at two Moroccan hospitals. Methods: This retrospective study included five skeletally immature patients (seven wrists) who underwent surgical treatment for Madelung deformity between January 2014 and July 2024. Patients underwent distal radial dome osteotomy, often combined with ulnar shortening osteotomy and Vickers ligament release. Outcomes were assessed using the Patient-Rated Wrist Evaluation, Visual Analog Scale for pain and satisfaction, range of motion measurements, and radiographic parameters. Results: The mean follow-up was 38.5 months. Postoperatively, improvements were observed in most range of motion parameters, particularly extension. The mean PRWE score improved, and patients reported high satisfaction with aesthetic outcomes. Radiographic parameters showed substantial corrections in ulnar tilt, lunate fossa angle, lunate subsidence, and palmar carpal displacement. Two wrists required reoperation due to complications or insufficient correction. Siblings with Léri-Weill syndrome demonstrated contrasting outcomes based on the timing of intervention and initial deformity severity. Conclusion: Combined radial and ulnar osteotomies improved pain, function, and radiographic parameters in adolescents with symptomatic Madelung deformity in the short to medium term. Early diagnosis and intervention may lead to better outcomes. Larger, prospective studies with longer follow-up are needed to establish optimal treatment algorithms and long-term outcomes. Level of Evidence Therapeutic Level IV. This was a retrospective case series. Madelung deformity congenital wrist condition osteotomy Léri-Weill syndrome Full Text Additional Declarations No competing interests reported. Cite Share Download PDF Status: Published Journal Publication published 18 Nov, 2025 Read the published version in Cureus → Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-7077906","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":485193062,"identity":"4d0be05e-275e-4df5-8faf-eb517b877ec0","order_by":0,"name":"Soufiane Essamoud","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAABEUlEQVRIiWNgGAWjYBADxgYg8SEBSPCDuAkFxGlhnAHSIgnSnGBArBYQy+AAmMStlJ//+MNPNyoOy85v7zFseFBzR874/OrEDw8MGOT5xQ5g1SI5I8dYOufMYeMNZ84YNiQce2ZsduPtZgmgwwxnzk7AqsXgBg+DdG7b4cQNEjnmDxLYDiduu3F2A0hLgsFt7Frszx9//BukZf6MHKAt/w7Xb55xdvMPfFqAUmZgWxpuALUkth1OMODv3YbXFokbOWbWOWfSgX45VtiQ2HfYcMYN3m0WCQYSOP3C33/88e2cCmtgiDVvbPzx7bA8f//ZzTd/VNjI80tj14LNYrBKCWKVgy0+QIrqUTAKRsEoGAEAAHfka1CgsujsAAAAAElFTkSuQmCC","orcid":"","institution":"Mohammed VI University of Sciences and Health","correspondingAuthor":true,"prefix":"","firstName":"Soufiane","middleName":"","lastName":"Essamoud","suffix":""},{"id":485193064,"identity":"74bae627-1d74-41f2-9810-38fe8e89a2a6","order_by":1,"name":"Mohamed Lahlou","email":"","orcid":"","institution":"Mohammed VI University of Sciences and Health","correspondingAuthor":false,"prefix":"","firstName":"Mohamed","middleName":"","lastName":"Lahlou","suffix":""},{"id":485193066,"identity":"1ee3b4a0-0739-4ac2-b57b-d3bd070b8965","order_by":2,"name":"Achraf Benmazhar","email":"","orcid":"","institution":"Mohammed VI University of Sciences and Health","correspondingAuthor":false,"prefix":"","firstName":"Achraf","middleName":"","lastName":"Benmazhar","suffix":""},{"id":485193068,"identity":"58a46b70-ad48-407d-8bdc-dd0f8d6dc76f","order_by":3,"name":"Rania Bennani","email":"","orcid":"","institution":"Mohammed VI University of Sciences and Health","correspondingAuthor":false,"prefix":"","firstName":"Rania","middleName":"","lastName":"Bennani","suffix":""},{"id":485193070,"identity":"d769e6a7-335a-4202-8596-7c4e6ebb3598","order_by":4,"name":"Mohamed Abdelwahed Kotb","email":"","orcid":"","institution":"Cairo University Hospitals","correspondingAuthor":false,"prefix":"","firstName":"Mohamed","middleName":"Abdelwahed","lastName":"Kotb","suffix":""},{"id":485193071,"identity":"10e856b8-1581-4ff7-861c-12d05f8a38b5","order_by":5,"name":"Hicham Zerhouni","email":"","orcid":"","institution":"Mohammed VI University of Sciences and Health","correspondingAuthor":false,"prefix":"","firstName":"Hicham","middleName":"","lastName":"Zerhouni","suffix":""},{"id":485193072,"identity":"25e3b000-4f2a-4657-b1db-417b16b81817","order_by":6,"name":"Abdelmounim Cherqaoui","email":"","orcid":"","institution":"Abderrahim Harouchi Mother and Child University Hospital","correspondingAuthor":false,"prefix":"","firstName":"Abdelmounim","middleName":"","lastName":"Cherqaoui","suffix":""}],"badges":[],"createdAt":"2025-07-08 20:23:18","currentVersionCode":1,"declarations":{"humanSubjects":false,"vertebrateSubjects":false,"conflictsOfInterestStatement":false,"humanSubjectEthicalGuidelines":false,"humanSubjectConsent":false,"humanSubjectClinicalTrial":false,"humanSubjectCaseReport":false,"vertebrateSubjectEthicalGuidelines":false},"doi":"10.21203/rs.3.rs-7077906/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-7077906/v1","draftVersion":[],"editorialEvents":[{"content":"https://doi.org/10.7759/cureus.97208","type":"published","date":"2025-11-19T00:00:00+00:00"}],"editorialNote":"","failedWorkflow":false,"files":[{"id":98952688,"identity":"0a11bfa6-c70b-4b08-b290-9701e49c7026","added_by":"auto","created_at":"2025-12-24 14:23:31","extension":"pdf","order_by":1,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":967903,"visible":true,"origin":"","legend":"","description":"","filename":"ManuscriptMadelungBMCv1.1.pdf","url":"https://assets-eu.researchsquare.com/files/rs-7077906/v1_covered_0030df22-72a6-4148-919f-58f52abd3e3e.pdf"}],"financialInterests":"No competing interests reported.","formattedTitle":"\u003cp\u003eSurgical Treatment of Madelung Deformity in Pediatric Patients: A Case Series\u003c/p\u003e","fulltext":[],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":false,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":true,"hideJournal":false,"highlight":"","institution":"","isAcceptedByJournal":true,"isAuthorSuppliedPdf":true,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":true,"isPdf":true,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"Madelung deformity, congenital wrist condition, osteotomy, Léri-Weill syndrome","lastPublishedDoi":"10.21203/rs.3.rs-7077906/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-7077906/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003ch2\u003eBackground:\u003c/h2\u003e\u003cp\u003eMadelung deformity is a rare congenital wrist condition characterized by premature growth arrest of the distal radial physis, leading to wrist deformity and functional limitations. This study aimed to assess short-term functional and radiological outcomes in patients with Madelung deformity treated surgically at two Moroccan hospitals.\u003c/p\u003e\u003ch2\u003eMethods:\u003c/h2\u003e\u003cp\u003eThis retrospective study included five skeletally immature patients (seven wrists) who underwent surgical treatment for Madelung deformity between January 2014 and July 2024. Patients underwent distal radial dome osteotomy, often combined with ulnar shortening osteotomy and Vickers ligament release. Outcomes were assessed using the Patient-Rated Wrist Evaluation, Visual Analog Scale for pain and satisfaction, range of motion measurements, and radiographic parameters.\u003c/p\u003e\u003ch2\u003eResults:\u003c/h2\u003e\u003cp\u003eThe mean follow-up was 38.5 months. Postoperatively, improvements were observed in most range of motion parameters, particularly extension. The mean PRWE score improved, and patients reported high satisfaction with aesthetic outcomes. Radiographic parameters showed substantial corrections in ulnar tilt, lunate fossa angle, lunate subsidence, and palmar carpal displacement. Two wrists required reoperation due to complications or insufficient correction. Siblings with L\u0026eacute;ri-Weill syndrome demonstrated contrasting outcomes based on the timing of intervention and initial deformity severity.\u003c/p\u003e\u003ch2\u003eConclusion:\u003c/h2\u003e\u003cp\u003eCombined radial and ulnar osteotomies improved pain, function, and radiographic parameters in adolescents with symptomatic Madelung deformity in the short to medium term. Early diagnosis and intervention may lead to better outcomes. Larger, prospective studies with longer follow-up are needed to establish optimal treatment algorithms and long-term outcomes.\u003c/p\u003e\u003ch2\u003eLevel of Evidence\u003c/h2\u003e\u003cp\u003eTherapeutic Level IV. This was a retrospective case series.\u003c/p\u003e","manuscriptTitle":"Surgical Treatment of Madelung Deformity in Pediatric Patients: A Case Series","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2025-07-15 09:57:12","doi":"10.21203/rs.3.rs-7077906/v1","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"7ba6d61b-bbf1-4f55-bee9-76c73cbe8ed6","owner":[],"postedDate":"July 15th, 2025","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"published-in-journal","subjectAreas":[],"tags":[],"updatedAt":"2025-12-24T14:23:07+00:00","versionOfRecord":{"articleIdentity":"rs-7077906","link":"https://doi.org/10.7759/cureus.97208","journal":{"identity":"cureus","isVorOnly":true,"title":"Cureus"},"publishedOn":"2025-11-19 00:00:00","publishedOnDateReadable":"November 19th, 2025"},"versionCreatedAt":"2025-07-15 09:57:12","video":"","vorDoi":"10.7759/cureus.97208","vorDoiUrl":"https://doi.org/10.7759/cureus.97208","workflowStages":[]},"version":"v1","identity":"rs-7077906","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-7077906","identity":"rs-7077906","version":["v1"]},"buildId":"8U1c8b4HqxoKbykW_rLl7","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

Ask this paper AI returns verbatim quotes from the full text · source: preprint-html

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Citation neighborhood (no data yet)

We don't have any in-corpus citations linked to this paper yet. This is a recent paper (2025) — citers typically take a year or two to land, and the OpenAlex reference graph may still be filling in.

Source provenance

europepmc
last seen: 2026-05-20T01:45:00.602351+00:00