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This study experimentally analyzed picosecond laser ablation of in vitro skin tissue, finding that increasing scanning speed reduces thermal damage, repeated scans increase ablation depth, and concentric scanning minimizes thermal accumulation.
Abstract
In view of the demand for ablation treatment by picosecond laser in the field of medical cosmetology, the degree of thermal damage between picosecond laser and skin tissue was analyzed by combining theoretical modeling with experimental research, An in vitro skin ablation experiment was carried out using a single-factor experimental method, and the effects of laser scanning speed, number of repeated scans, and scanning path on the range of the heat-affected zone, ablation depth and cumulative effect of thermal damage were analyzed. The results show that increasing the scanning speed can reduce the heat-affected zone; the number of repeated scans is positively correlated with the ablation depth; and the concentric circle scanning path can reduce the accumulation of thermal damage compared with linear scanning. A multi-objective optimization model was constructed based on the above law to provide a theoretical basis for the optimization of clinical picosecond laser treatment parameters.
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Technique of picosecond laser ablation in vitro skin tissue | Authorea try { document.documentElement.classList.add('js'); } catch (e) { } var _gaq = _gaq || []; _gaq.push(['_setAccount', 'G-8VDV14Y67G']); _gaq.push(['_trackPageview']); (function() { var ga = document.createElement('script'); ga.type = 'text/javascript'; ga.async = true; ga.src = ('https:' == document.location.protocol ? 'https://ssl' : 'http://www') + '.google-analytics.com/ga.js'; var s = document.getElementsByTagName('script')[0]; s.parentNode.insertBefore(ga, s); })(); Skip to main content Preprints Collections Wiley Open Research IET Open Research Ecological Society of Japan All Collections About About Authorea FAQs Contact Us Quick Search anywhere Search for preprint articles, keywords, etc. Search Search ADVANCED SEARCH SCROLL Journal of Biophotonics This is a preprint and has not been peer reviewed. Data may be preliminary. 11 April 2025 V1 Latest version Share on Technique of picosecond laser ablation in vitro skin tissue Authors : Zhan Jinming 0009-0008-4522-3781 , Wu Xuefeng [email protected] , Yang Lijun , Ding Ye , and Liu Weiting Authors Info & Affiliations https://doi.org/10.22541/au.174438096.69509483/v1 267 views 167 downloads Contents Abstract Supplementary Material Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract In view of the demand for ablation treatment by picosecond laser in the field of medical cosmetology, the degree of thermal damage between picosecond laser and skin tissue was analyzed by combining theoretical modeling with experimental research, An in vitro skin ablation experiment was carried out using a single-factor experimental method, and the effects of laser scanning speed, number of repeated scans, and scanning path on the range of the heat-affected zone, ablation depth and cumulative effect of thermal damage were analyzed. The results show that increasing the scanning speed can reduce the heat-affected zone; the number of repeated scans is positively correlated with the ablation depth; and the concentric circle scanning path can reduce the accumulation of thermal damage compared with linear scanning. A multi-objective optimization model was constructed based on the above law to provide a theoretical basis for the optimization of clinical picosecond laser treatment parameters. Supplementary Material File (technique of picosecond laser ablation in vitro skin tissue.docx) Download 3.78 MB Information & Authors Information Version history V1 Version 1 11 April 2025 Copyright This work is licensed under a Non Exclusive No Reuse License. Collection Journal of Biophotonics Keywords picosecond laser process optimization scanning path skin tissue ablation thermal damage Authors Affiliations Zhan Jinming 0009-0008-4522-3781 Harbin University of Science and Technology View all articles by this author Wu Xuefeng [email protected] Harbin University of Science and Technology View all articles by this author Yang Lijun Harbin Institute of Technology View all articles by this author Ding Ye Harbin Institute of Technology View all articles by this author Liu Weiting Harbin University of Science and Technology View all articles by this author Metrics & Citations Metrics Article Usage 267 views 167 downloads .FvxKWukQNSOunydq8rnd { width: 100px; } Citations Download citation Zhan Jinming, Wu Xuefeng, Yang Lijun, et al. Technique of picosecond laser ablation in vitro skin tissue. Authorea . 11 April 2025. 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