Dienogest increases the progesterone receptor isoform B/A ratio in patients with ovarian endometriosis

This dissertation studied how dienogest treatment affects progesterone receptor expression in patients with ovarian endometriosis, focusing specifically on the progesterone receptor isoform B/A ratio. Using patient samples collected before and after dienogest exposure, the study found that dienogest increased the progesterone receptor B/A ratio. A key limitation is that the work is based on the enrolled patient cohort and focuses on progesterone receptor isoform ratio changes rather than directly demonstrating broader functional outcomes. This paper is centrally about endometriosis — it investigates how dienogest alters progesterone receptor isoform B/A ratio in ovarian endometriosis patients.

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