Instrumented gait analysis of stroke patients after FES-cycling therapy. | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Short report Instrumented gait analysis of stroke patients after FES-cycling therapy. PATRICIO BARRIA, ROLANDO AGUILAR, DAYA SERRANO DELGADO, ANDRE MORIS, and 2 more This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-47638/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract Background : Functional electrical stimulation (FES) is a modality of motor rehabilitation that consists of the programmed application of bursts of electrical current to the a ected neuromuscular region that aims to improve muscle strength, increase the range of motion, facilitate movement control and decrease spasticity. The present study aimed to measure the changes in gait biomechanics of people with Stroke after a FES-cycling rehabilitation program for the lower extremities. Methods : 39 subjects with chronic stroke received 24 sessions of multi-channel FES synchronized with a cycle-ergometer for the lower extremities. The gait of all subjects was evaluated before and after the intervention by an instrumented gait analysis. Results : Signifcant changes were found in the spatio-temporal parameters of gait, mainly in the speed and stride length when considering the general sample. Additionally, in people under 60 years of age, there are signi cant changes in joint kinematics after FES. Conclusions : The rehabilitation using a multi-channel FES-cycling system for lower extremities improve gait biomechanics in people with Stroke. Trial registration : This study was registered as Instrumental Gait Analysis on People With Stroke After Rehabilitation With a Synchronized FES and Cycle-Ergometer System on July 16, 2020 in Clinical Trials with the identier No NCT04473391 (available at https://clinicaltrials.gov/ct2/show/NCT04473391). Physical Medicine & Rehab Biotechnology and Bioengineering Stroke gait rehabilitation functional electrical stimulation cycling Figures Figure 1 Figure 2 Figure 3 Figure 4 Full Text Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-47638","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Short report","associatedPublications":[],"authors":[{"id":990071,"identity":"b8f44733-1dc1-472d-9103-0c3c96685d18","order_by":0,"name":"PATRICIO BARRIA","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAABB0lEQVRIiWNgGAWjYDACCRBhwCDHwMDDwMxgYMFDtBZjqBYJHsJ6JCBUYgNYC5BLUIu5dPOzzxUFdunb23sPfi4okJCxZz+d+PAHg02+vAN2LZZzjhnPPGOQnDvnzLlk6Rkgh/HkbjbmYUiz3HgAuxaDGwnGjA0GzLkzJHIMpHnAfsndJs3AcNjAsAGXlvTPQC316RLyb4x/g7Xwv90m+QOvlhyQLYcTJCR4zCC2SORuk+ABapHH4X3LOWeKgVqOG87gyTGzBvvlxlugXwzSDAxwhlj7ZsaGP9XyEuxnjG8X/LGxZ+/P3fjwR4WNgTwuh+EwCihucIA0LUCAy5ZRMApGwSgYcQAAV1VNhU/614oAAAAASUVORK5CYII=","orcid":"https://orcid.org/0000-0003-4088-9820","institution":"Corporación de Rehabilitacion Club de Leones Cruz del Sur","correspondingAuthor":true,"submittingAuthor":false,"prefix":"","firstName":"PATRICIO","middleName":"","lastName":"BARRIA","suffix":""},{"id":990072,"identity":"68e0586b-4937-4fbc-820d-c5f953bdeb01","order_by":1,"name":"ROLANDO AGUILAR","email":"","orcid":"","institution":"Universidad de Magallanes","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"ROLANDO","middleName":"","lastName":"AGUILAR","suffix":""},{"id":990073,"identity":"75536a41-e40b-46db-8e10-802d91cd3213","order_by":2,"name":"DAYA SERRANO DELGADO","email":"","orcid":"","institution":"Escuela Colombiana de Ingenieria Julio Garavito","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"DAYA","middleName":"SERRANO","lastName":"DELGADO","suffix":""},{"id":990074,"identity":"2589b3ce-9cb3-411d-9f98-92fbc1ec7f9e","order_by":3,"name":"ANDRE MORIS","email":"","orcid":"","institution":"Corporación de Rehabilitación Club de Leones Cruz del Sur","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"ANDRE","middleName":"","lastName":"MORIS","suffix":""},{"id":990075,"identity":"381a2541-1207-4894-97af-b6cdbb1549bc","order_by":4,"name":"ASTERIO ANDRADE","email":"","orcid":"","institution":"Corporacion de Rehabilitación Club de Leones Cruz del Sur","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"ASTERIO","middleName":"","lastName":"ANDRADE","suffix":""},{"id":990076,"identity":"ccf7634e-3552-490d-a856-4c1fa7e79f26","order_by":5,"name":"JOSE M AZORIN","email":"","orcid":"","institution":"Universidad Miguel Hernandez de Elche","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"JOSE","middleName":"M","lastName":"AZORIN","suffix":""}],"badges":[],"createdAt":"2020-07-22 12:23:30","currentVersionCode":1,"declarations":"","doi":"10.21203/rs.3.rs-47638/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-47638/v1","draftVersion":[],"editorialEvents":[],"editorialNote":"","failedWorkflow":false,"files":[{"id":1701037,"identity":"cd3f376f-79ef-4ba7-91e3-66609e0c516b","added_by":"auto","created_at":"2020-07-28 01:21:53","extension":"png","order_by":1,"title":"Figure 1","display":"","copyAsset":false,"role":"figure","size":358127,"visible":true,"origin":"","legend":"Patient setup for FES-cycling therapy. The \fgure presents (A) 6-channel electrical stimulator; (B) Adhesive electrodes on lower limb muscle; (C) Inertial measurement unit (IMU) positioned on the rotation axis of the cycle-ergometer, and (D) Motorized cycle-ergometer for lower limbs","description":"","filename":"fessetup.png","url":"https://assets-eu.researchsquare.com/files/rs-47638/v1/fessetup.png"},{"id":1701038,"identity":"0816beb3-36b2-40be-893e-edea71f984a3","added_by":"auto","created_at":"2020-07-28 01:21:53","extension":"png","order_by":2,"title":"Figure 2","display":"","copyAsset":false,"role":"figure","size":379699,"visible":true,"origin":"","legend":"Reflective markers positioning of the Plug-in-Gait model. The white circles on the lower\nlimbs and pelvis of the subjects correspond to the spherical reflective markers of the\noptoelectronic camera system.","description":"","filename":"viconmarkers.png","url":"https://assets-eu.researchsquare.com/files/rs-47638/v1/viconmarkers.png"},{"id":1701039,"identity":"a3187a98-3d67-4695-96b1-1cca470b60d1","added_by":"auto","created_at":"2020-07-28 01:21:53","extension":"png","order_by":3,"title":"Figure 3","display":"","copyAsset":false,"role":"figure","size":39747,"visible":true,"origin":"","legend":"FES-cycling therapy effects on biomechanical variables in the total sample. The \ffigure\npresents the graphs of the averaged values of GDI in the paretic limb (P), GDI in non-paretic limb (N-P), Walking speed, and Stride Length at Baseline and Post-FES \n conditions.","description":"","filename":"sampleresults.png","url":"https://assets-eu.researchsquare.com/files/rs-47638/v1/sampleresults.png"},{"id":1701040,"identity":"2be3afa6-f112-4b99-8598-d7d9a91ab6f7","added_by":"auto","created_at":"2020-07-28 01:21:53","extension":"png","order_by":4,"title":"Figure 4","display":"","copyAsset":false,"role":"figure","size":39699,"visible":true,"origin":"","legend":"FES-cycling therapy effects on biomechanical variables in the group under 60 years of\nage. The \ffigure presents the graphs of the averaged values of GDI in the paretic limb (P), GDI in non-paretic limb (N-P), Walking speed, and Stride Length at Baseline and Post-FES conditions.","description":"","filename":"subgroupresults.png","url":"https://assets-eu.researchsquare.com/files/rs-47638/v1/subgroupresults.png"},{"id":13518234,"identity":"26f58e92-314d-4ca0-8726-f46b73f54a3f","added_by":"auto","created_at":"2021-09-17 00:19:07","extension":"pdf","order_by":1,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":423179,"visible":true,"origin":"","legend":"","description":"","filename":"Manuscript.pdf","url":"https://assets-eu.researchsquare.com/files/rs-47638/v1_covered.pdf"},{"id":1701042,"identity":"0e61e209-bf7e-4c73-84d9-330a74fd309f","added_by":"auto","created_at":"2020-07-28 01:21:54","extension":"pdf","order_by":1,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":288855,"visible":true,"origin":"","legend":"","description":"","filename":"Manuscript.pdf","url":"https://assets-eu.researchsquare.com/files/rs-47638/v1_stamped.pdf"},{"id":1701041,"identity":"58e4ef77-f9f4-490e-8be8-cd2800b3af3b","added_by":"auto","created_at":"2020-07-28 01:21:53","extension":"pdf","order_by":1,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":244832,"visible":true,"origin":"","legend":"","description":"","filename":"Manuscript.pdf","url":"https://assets-eu.researchsquare.com/files/rs-47638/v1/Manuscript.pdf"}],"financialInterests":"","formattedTitle":"Instrumented gait analysis of stroke patients after FES-cycling therapy.","fulltext":[{"header":"Full Text","content":"\u003cp\u003eThis preprint is available for \u003ca href='/article/rs-47638/latest.pdf' target='_blank'\u003edownload as a PDF\u003c/a\u003e.\u003c/p\u003e"}],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":false,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":true,"highlight":"","institution":"","isAcceptedByJournal":false,"isAuthorSuppliedPdf":true,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":false,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"
[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"Stroke, gait, rehabilitation, functional electrical stimulation, cycling","lastPublishedDoi":"10.21203/rs.3.rs-47638/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-47638/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003e\u003cstrong\u003eBackground\u003c/strong\u003e: Functional electrical stimulation (FES) is a modality of motor rehabilitation that consists of the programmed application of bursts of electrical\u0026nbsp;current to the a ected neuromuscular region that aims to improve muscle strength, increase the range of motion, facilitate movement control and decrease spasticity. The present study aimed to measure the changes in gait biomechanics of people with Stroke after a FES-cycling rehabilitation program for the lower extremities. \u003c/p\u003e\u003cp\u003e\u003cstrong\u003eMethods\u003c/strong\u003e: 39 subjects with chronic stroke received 24 sessions of multi-channel FES synchronized with a cycle-ergometer for the lower extremities. The gait of all subjects was evaluated before and after the intervention by an instrumented gait analysis. \u003c/p\u003e\u003cp\u003e\u003cstrong\u003eResults\u003c/strong\u003e: Signifcant changes were found in the spatio-temporal parameters of gait, mainly in the speed and stride length when considering the general sample. Additionally, in people under 60 years of age, there are signi cant changes in joint kinematics after FES. \u003c/p\u003e\u003cp\u003e\u003cstrong\u003eConclusions\u003c/strong\u003e: The rehabilitation using a multi-channel FES-cycling system for lower extremities improve gait biomechanics in people with Stroke. \u003c/p\u003e\u003cp\u003e\u003cstrong\u003eTrial registration\u003c/strong\u003e: This study was registered as Instrumental Gait Analysis on People With Stroke After Rehabilitation With a Synchronized FES and Cycle-Ergometer System on July 16, 2020 in Clinical Trials with the identier No NCT04473391 (available at https://clinicaltrials.gov/ct2/show/NCT04473391). \u003c/p\u003e","manuscriptTitle":"Instrumented gait analysis of stroke patients after FES-cycling therapy.","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2020-07-28 01:21:52","doi":"10.21203/rs.3.rs-47638/v1","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"
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