Diagnostic accuracy of hysterosalpingography and laparoscopy in tubal patency

In: International Journal of Reproduction, Contraception, Obstetrics and Gynecology · 2022 · vol. 11(2) , pp. 543 · doi:10.18203/2320-1770.ijrcog20220062 · W4205485042
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This study found hysterosalpingography (HSG) has 91.3% sensitivity, 88.9% specificity, and 89.7% diagnostic accuracy for tubal patency compared to laparoscopy.

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This prospective study evaluated the diagnostic accuracy of hysterosalpingography (HSG) compared to laparoscopy for assessing tubal patency in infertile women. The research included patients aged 20 to 30 years with regular menses and normal semen analysis, while explicitly excluding individuals with a history of endometriosis. Results indicated that HSG demonstrated high sensitivity and specificity, suggesting it is a satisfactory, cost-effective alternative to the invasive gold standard of laparoscopy for identifying tubal factors of infertility. Relevance to endometriosis: The paper excludes patients with endometriosis from its study population rather than studying the condition itself.

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Abstract

Background: There is no doubt that health care providers face a great deal of challenge to deal with the infertility issue, a serious and tragic gynecological problem encountered in developing countries. Laparoscopy is considered as the gold standard for assessment of tubal factors of infertility, although because of its invasive nature, cost and the need for anaesthesia and hospitalization, HSG seems to be a basic routine procedure for tubal factors. Hence, the present study was designed to compare the accuracy of HSG with SSG for evaluation of tubal factor infertility. Laparoscopy is considered as the gold standard for assessment of tubal factors of infertility, although because of its invasive nature, cost and the need for anaesthesia and hospitalization, HSG seems to be a basic routine procedure for tubal factors. Currently with the availability of the ultrasonography machines with very good resolution, SSG can be simultaneously practiced with ultrasonography during day 7-9 of the menstrual cycle to assess tubal patency. Hence, the present study was designed to compare the accuracy of HSG with laparoscopyfor evaluation of tubal factor infertility.Methods: The present prospective study on the diagnostic accuracy of hysterosalpingography (HSG) in the evaluation of infertility due to tubal patency has been conducted at Lala-Ded Hospital, Srinagar from September 2015 to February 2016. All the patients with infertility having regular menses, normal male partner with semen analysis and aging 20-30 years old have been included in the study. However, females who underwent HSG previously, case of unovulation despite clomiphene citrate, acute PID, salpingectomy, endometriosis, past history of oophorectomy and women beyond 35 years of age have been excluded in this study.Results: The average age of patients was observed as (26.7±4.81) years with majority of patients belonging to (25-29) year age group. We performed sensitivity analysis of HSG procedure by taking laparoscopic findings as gold standard; evidently, we found the sensitivity and specificity of HSG as 91.3% and 88.9% respectively. Interestingly, the diagnostic accuracy of HSG was observed as 89.7%.Conclusions: We found that HSG has satisfactory predictive value in identifying the factor of infertility. Laparoscopy is still a gold standard but if the purpose is attained with minimally invasive and cost-effective procedure having a good accuracy rate then over diagnosis should be avoided.
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Background

There is no doubt that health care providers face a great deal of challenge to deal with the infertility issue, a serious and tragic gynecological problem encountered in developing countries. Laparoscopy is considered as the gold standard for assessment of tubal factors of infertility, although because of its invasive nature, cost and the need for anaesthesia and hospitalization, HSG seems to be a basic routine procedure for tubal factors. Hence, the present study was designed to compare the accuracy of HSG with SSG for evaluation of tubal factor infertility. Laparoscopy is considered as the gold standard for assessment of tubal factors of infertility, although because of its invasive nature, cost and the need for anaesthesia and hospitalization, HSG seems to be a basic routine procedure for tubal factors. Currently with the availability of the ultrasonography machines with very good resolution, SSG can be simultaneously practiced with ultrasonography during day 7-9 of the menstrual cycle to assess tubal patency. Hence, the present study was designed to compare the accuracy of HSG with laparoscopyfor evaluation of tubal factor infertility.

Methods

The present prospective study on the diagnostic accuracy of hysterosalpingography (HSG) in the evaluation of infertility due to tubal patency has been conducted at Lala-Ded Hospital, Srinagar from September 2015 to February 2016. All the patients with infertility having regular menses, normal male partner with semen analysis and aging 20-30 years old have been included in the study. However, females who underwent HSG previously, case of unovulation despite clomiphene citrate, acute PID, salpingectomy, endometriosis, past history of oophorectomy and women beyond 35 years of age have been excluded in this study.

Results

The average age of patients was observed as (26.7±4.81) years with majority of patients belonging to (25-29) year age group. We performed sensitivity analysis of HSG procedure by taking laparoscopic findings as gold standard; evidently, we found the sensitivity and specificity of HSG as 91.3% and 88.9% respectively. Interestingly, the diagnostic accuracy of HSG was observed as 89.7%.

Conclusions

We found that HSG has satisfactory predictive value in identifying the factor of infertility. Laparoscopy is still a gold standard but if the purpose is attained with minimally invasive and cost-effective procedure having a good accuracy rate then over diagnosis should be avoided. Metrics

References

Adamson PC, Krupp K, Freeman AH, Klausner JD, Reingold AL, Madhivanan P. Prevalence & correlates of primary infertility among young women in Mysore, India. Indian J Med Res. 2011;134:440-6. Sami N, Ali TS, Wasim S, Saleem S. Risk factors for secondary infertility among women in Karachi, Pakistan. PLoS One. 2012;7(4):e35828. Lindsay TJ, Vitrikas KR. Evaluation and treatment of infertility. Am Fam Phys. 2015;91:308-14. Otta SP, Reddy RG, Sangvikar S, Tripathy R. Ayurvedic management of female infertility due to tubal blockage. J Complement Integr Med. 2021. Robabeh M, Roozbeh T. Comparison of hysterosalpingography and laparoscopy in infertile Iranian women with tubal factor. Ginekol Pol. 2012;83(11):841-3. Sakar MN, Gul T, Atay AE, Celik Y. Comparison of hysterosalpingography and laparoscopy in the evaluation of infertile women. Saudi Med J. 2008;29(9):1315-8. Farideh G, Rastegar F. Comparison of hysterosalpingography and laparoscopy in evaluation of female infertility. Med Res Arch. 2017;5(6):1-12. Fayez JA, Mutie G, Schneider PJ. The diagnostic value of hysterosalpingography and laparoscopy in infertility investigation. Int J Ferti. 1988;33(2):98-101. Jain P, Bansal D, Deodhar P. Reemerging role of HSG Vs laparoscopy for infertility work– up at rural hospital set up. J Res Med Den Sci. 2015;3(4):287-9. Tvarijonaviciene E, Nadisauskiene RJ. The value of hysterosalpingography in the diagnosis of tubal pathology among infertile patients. Medicina (Kaunas). 2008;44(6):439-48. Vasiljevic M, Ganovic R, Jovanovic R, Markovic A. Diagnostic value of hysterosalpingography and laparoscopy in infertile women. Srp Arh Celok Lek. 1996;124(5-6):135-8.

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