The Efficacy and Safety of Minimally Invasive Surgery Combined GnRH-a in the Treatment of Endometriosis

Objective To explore the efficacy and safety studies of minimally invasive surgery combined GnRH-a in the treatment of endometriosis. Methods 80 cases that came to our hospital from February 2010 to February 2012 with endometriosis were collected. All the patients were randomly divided into control group and experimental group. 40 cases of the control group received laparoscopic surgery and conventional anti-inflammatory drug and oral contraceptives. 40 cases patients of the experimental group received minimally invasive surgery and on the basis of conventional anti-inflammatory drug,GnRH-a add-back treatment was used.Then the clinical efficacy and relapse rate of the two groups were compared. Results The efficiency of the experimental group( 85%) was higer than the control group( 45%),and the difference of the two group was statistically significant( P 0. 05). The recurrence rate of the experimental group( 7. 5%) was lower than the control group( 32. 5%),and the difference of the two group was statistically significant( P 0. 05). The pregnancy of the experimental group( 40. 9%) was higher than the control group( 34. 8%),and the difference of the two group was not statistically significant( P 0. 05). The adverse drug reactions of the experimental group was10%,and the difference of the two group was not statistically significant( P 0. 05). Conclusion Minimally invasive surgery combined GnRH-a in the treatment of endometriosis is safe and efficient.