Incidence of Epilepsy and Evaluation of Associated Disorders in Elderly People of Amirkola, North of Iran

Introduction: The aim of this study was to determine the incidence of epilepsy in the elderly and investigating the disorders associated with its occurrence. Methods and Materials: This cross-sectional study using a census sampling method, is a part of a comprehensive and cohort research of "Amirkola Health and Ageing Project". Cognitive impairment using Mini Mental State Examination (M.M.S.E). and psychiatric diseases based on relevant tests such as Geriatric Depression Scale G.D.S. Physical activity was measured based on the standard physical activity questionnaire for elderly Physical Activity Scale for Elderly(PASE). All data were analyzed using chi-square test and logistic regression in SPSS v23 software. Results: Of 1482 participants 35 subjects were epileptic. the incidence was 2.36 in 1,000 of the elderly. Significant association between Parkinson’s Disease(p=0.001), falls (p=0.001, depression(p=0.001), hyperphosphoremia(p= 0.039) and hypokalaemia (p= 0.031) concluded with epilepsy. Past history of stroke and serum (triglyceride,LDL) level in epileptic were more than the no epileptics. Conclusion: significant association between Parkinson's Disease, frequency of fall, depression and correlation of history of stroke, increased serum triglyceride level and higher serum level of LDL with epilepsy concluded.