An unusual presentation of Wegener disease of the cervix: presenting as cervical cancer

Oladipo A, Abi Oladipo, Sahathevan Sathiyathasan, Sathiyathasan S, Syamala Thomas, Thomas S, Jeyanthan K, Kannapar Jeyanthan, Hakeem-Habeeb Y, Yewnade Hakeem-Habeeb
Journal of lower genital tract disease · 2011 · vol. 15(4) , pp. 328–30 · doi:10.1097/lgt.0b013e31821380bd · PMID:21959576
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⚙ AI-generated summary by qwen3.7-flash, 2026-09-07 ⓘ

This case report describes the first instance of Wegener granulomatosis involving the uterine cervix without prior systemic involvement, presenting clinically as cervical cancer.

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⚙ AI-generated deep summary by qwen3.7-flash, 2026-08-23 · read from full text ⓘ

This case report describes a rare instance of Wegener granulomatosis manifesting in the uterine cervix, mimicking cervical cancer. The authors present the first documented case where the disease involved the cervix without any prior diagnosis or treatment affecting other organs such as the respiratory tract or kidneys. A review of existing literature highlights that cervical involvement is exceptionally uncommon, with only four previous cases reported before this one. This paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

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Abstract

OBJECTIVE: : Wegener granulomatosis is a rare autoimmune disease of unknown cause. It commonly affects the respiratory tracts, lungs, and kidneys.Involvement of the uterine cervix is rare, with only 4 previously published cases in the literature. MATERIALS AND METHODS: : This is a case report. RESULT: : We describe the unusual presentation of Wegener granulomatosis involving the uterine cervix, presenting as cervical cancer. CONCLUSIONS: : A review of previously published cases of Wegener granulomatosis involving the uterine cervix is presented.We report the first case of Wegener granulomatosis involving the cervix without antecedent diagnosis or treatment of Wegener granuloma in any other organ.
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Objective

Wegener granulomatosis is a rare autoimmune disease of unknown cause. It commonly affects the respiratory tracts, lungs, and kidneys. Involvement of the uterine cervix is rare, with only 4 previously published cases in the literature.

Materials and methods

This is a case report.

Result

We describe the unusual presentation of Wegener granulomatosis involving the uterine cervix, presenting as cervical cancer.

Conclusions

A review of previously published cases of Wegener granulomatosis involving the uterine cervix is presented. We report the first case of Wegener granulomatosis involving the cervix without antecedent diagnosis or treatment of Wegener granuloma in any other organ. We present an unusual case of Wegener granuloma, which, to the best of our knowledge, is the first documented case involving the cervix without antecedent granulomatosis diagnosed in any other organ. Copyright ©2011The American Society for Colposcopy and Cervical Pathology

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MeSH descriptors

Cervix Uteri Granulomatosis with Polyangiitis Uterine Cervical Neoplasms Aged Cervix Uteri Diagnosis, Differential Female Granulomatosis with Polyangiitis Granulomatosis with Polyangiitis Histocytochemistry Humans Immunohistochemistry Magnetic Resonance Imaging Microscopy Pelvis Pelvis Radiography, Abdominal Uterine Cervical Neoplasms Uterine Cervical Neoplasms Vasculitis

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pubmed
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