Controlled Ovarian Stimulation for Intra-uterine Insemination

When intra-uterine insemination (IUI) is chosen for the treatment of mild male factor infertility or idiopathic (unexplained) infertility, there are a number of options for ovarian stimulation for these women who are usually ovulating spontaneously. There is now general agreement that for pure mild male factor infertility (sperm concentration 5–15 million/ml and/or progressive motility 20–32 %), whether the ovaries are stimulated or not before IUI makes very little difference to the results. For unexplained infertility, stimulated cycles in combination with IUI are more effective than unstimulated cycles as regards pregnancy rates. The combination of IUI with stimulated cycles, although improving pregnancy rates, is often accompanied by unacceptable multiple pregnancy rates. With ovarian stimulation with gonadotrophins, I aim to achieve a maximum of two ovulatory follicles and this with strict criteria for administering hCG seems to give optimal results with minimal twinning rates. Access this chapter Tax calculation will be finalised at checkout Purchases are for personal use only Similar content being viewed by others

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- Ovarian Stimulation - Intra-uterine Insemination - Ovulation - Dominant ovulatory follicle - FSH - Ovulation induction - Multifollicular - Ovarian response - Multiple pregnancies - Ovarian hyperstimulation syndrome - IVF - Oocytes - Fertilization - Embryo replacement - Oestradiol - GnRH agonist - Antagonist - ICSI - Intra-uterine insemination IUI - Letrozole - Gonadotrophin - Idiopathic infertility - hMG - Monofollicular - Multiple pregnancy rate - Ovulatory follicles - Premature luteinization - Unexplained infertility