Assay characteristics of the immunoradiometric method for CA-125

D E Pittaway, Pittaway DE
Fertility and sterility · 1989 · doi:10.1016/s0015-0282(16)60504-6 · PMID:2912782
other OA: closed public-domain-us
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⚙ AI-generated summary by gemini-2.5-flash-lite, 2026-07-05 ⓘ

This study describes a modification to the immunoradiometric assay for CA-125 that corrects nonlinear standard curve issues and prevents overestimation of values below 20 U/ml.

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Abstract

A nonlinear standard curve for the immunoradiometric method for determining CA-125 may result in an overestimation of values below 20 U/ml. Since the modification of the assay as described in the report eliminates the problem, we propose the use of this simple modification when using CA-125 determinations for evaluating women with endometriosis.

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Condition tags

endometriosis

MeSH descriptors

Antigens, Tumor-Associated, Carbohydrate Adult Antigens, Tumor-Associated, Carbohydrate Female Humans Radioimmunoassay Radioimmunoassay Reagent Kits, Diagnostic

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Source provenance

europepmc
last seen: 2026-10-01T06:15:55.914501+00:00
pubmed
last seen: 2026-05-13T22:09:15.954262+00:00
unpaywall
last seen: 2026-08-14T06:25:32.811723+00:00
License: public-domain-us · commercial use OK · attribution required
Courtesy of the U.S. National Library of Medicine