Microscopic Uterine Lymphangioleiomyomatosis Perivascular Epithelioid Cell Neoplasm

Clay MR; Michael R. Clay; Pamela Gibson; Gibson P; Pamela Church Gibson; Lowell J; Jennifer L. Lowell; Jennifer Lowell; Kumarasen Cooper; Cooper K

doi:10.1097/pgp.0b013e3181efe08d

Microscopic Uterine Lymphangioleiomyomatosis Perivascular Epithelioid Cell Neoplasm

Clay MR, Michael R. Clay, Pamela Gibson, Gibson P, Pamela Church Gibson, Lowell J, Jennifer L. Lowell, Jennifer Lowell, Kumarasen Cooper, Cooper K

International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists · 2010 · vol. 30(1) , pp. 71–75 · doi:10.1097/pgp.0b013e3181efe08d · PMID:21131829 · W2329102939

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Researchers describe a unique microscopic uterine PEComa, potentially an early example of LAM, and compare its features to other intravascular uterine neoplasms.

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Abstract

Lymphangioleiomyomatosis (LAM) is part of a family of lesions collectively known as perivascular epithelioid cell neoplasms (PEComas). Though these lesions are comprised of histologically and immunohistochemically distinctive perivascular epithelioid cells, their diagnosis is controversial and some investigators question their existence entirely. We present a unique case of perhaps the earliest microscopic example of a LAM PEComa in the uterine myometrium, and contrast its features to that of intravascular adenomyosis, intravascular endometrial stromal sarcoma, and intravascular leiomyoma.

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Condition tags

adenomyosis

MeSH descriptors

Lymphangioleiomyomatosis Myometrium Uterine Neoplasms Epithelioid Cells Epithelioid Cells Female Humans Lymphangioleiomyomatosis Middle Aged Myometrium Uterine Neoplasms

Citation neighborhood (sparse)

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Cites (1)

Vascular Involvement in Adenomyosis: Report of a Large Series of a Common Phenomenon With Observations on the Pathogenesis of Adenomyosis 2010

References (9)

Vascular Involvement in Adenomyosis: Report of a Large Series of a Common Phenomenon With Observations on the Pathogenesis of Adenomyosis via openalex
W1975275335 via openalex
W1987661952 via openalex
W2030236984 via openalex
W2051836645 via openalex
W2067955512 via openalex
W2076689243 via openalex
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[1] Vascular Involvement in Adenomyosis: Report of a Large Series of a Common Phenomenon With Observations on the Pathogenesis of Adenomyosis 2010