Design and Analysis of CompactSubstrate-Integrated Waveguide (SIW)Cavity Resonator Based MicrofluidicBiosensor for X-Band Applications

Design and Analysis of CompactSubstrate-Integrated Waveguide (SIW)Cavity Resonator Based MicrofluidicBiosensor for X-Band Applications | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article Design and Analysis of CompactSubstrate-Integrated Waveguide (SIW)Cavity Resonator Based MicrofluidicBiosensor for X-Band Applications Saranya S, Sharmila B, Jeyakumar P, Muthuchidambaranathan P This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-1830533/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract Biosensors are compact miniaturized devices to measure the biologicalsamples based on the molecular structure and convert the sameto electronic signals. The substrate Integrated Waveguide (SIW) cavitybased resonators loaded with a circular cavity can be used as a biosensorin a non invasive manner to detect the biological tissues in the sample with better efficiency and miniaturized structure.The biosensingsamples may vary from proteins to enzymes which has gained ahuge response in the industries likes medical, agriculture, food processingindustry and many more over the decades. The substrate materialof antenna is designed with Rogers RT/Duroid 5870 which has thedielectric constant of 2.33. The Rectangular patch antenna is thenloaded with the SIW vias for an enhanced performance of S parameterfrom -17.21 dB to -44.88dB operating at the X band (8 to 12GHz) frequencies. The microwell made from the Polydimethylsiloxane(PDMS) material is inserted into the patch infrom of circularslot to achieve the biosensing application. The microwell based SIWcavity is then simulated for different diameters of PDMS to improvethe S11 parameter and Voltage standing wave ratio. The fabricatedantenna is tested to work in the TE110 mode at a resonant frequencyof 12.12GHZ with a improved return loss characteristics of -42.45 dB Biosensors microwell substrate integrated waveguide (SIW) Polydimethylsiloxane (PDMS) Full Text Additional Declarations No competing interests reported. Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. 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Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-1830533","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":119111147,"identity":"03ba1a2f-aa05-4aa5-b4fc-7b84b8cee709","order_by":0,"name":"Saranya S","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAA3UlEQVRIiWNgGAWjYFAD9gYYi7EBtyoUwHOAZC0SCUQqlG8/+/BzYZsdg/zM588+fKhhkOdvYG57gE+LwZl0Y+mZbckMBrdzjGfOOMZgOOMAY7sBXi0MaQzSvG3MDAbSOczMvA0MjBsYGNsk8Dqs/xnzb962eqDDjj9m/tvAYE9QC8ONNDagLYeBDAZjZmBYJRLUYnDjGZs1z7njPAZncowZe45JJM84TNBhacy3ecqq5eTbjz9m+FFjY9vf3v4Mv8NAgJGNgQfKBCpmJqgeBP4QpWoUjIJRMApGKgAAgrg+joJv/2kAAAAASUVORK5CYII=","orcid":"","institution":"Sri Ramakrishna Engineering College","correspondingAuthor":true,"submittingAuthor":false,"prefix":"","firstName":"Saranya","middleName":"","lastName":"S","suffix":""},{"id":119111148,"identity":"8a3ee482-328f-44be-b3f8-f56cb1809c3c","order_by":1,"name":"Sharmila B","email":"","orcid":"","institution":"Sri Ramakrishna Engineering College","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Sharmila","middleName":"","lastName":"B","suffix":""},{"id":119111149,"identity":"6c3b3c4e-1789-4859-9ab7-7fd003498a5d","order_by":2,"name":"Jeyakumar P","email":"","orcid":"","institution":"M.Kumarasamy College of Engineering","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Jeyakumar","middleName":"","lastName":"P","suffix":""},{"id":119111150,"identity":"6c4438d3-a148-4861-ab87-321ea80b4a3b","order_by":3,"name":"Muthuchidambaranathan P","email":"","orcid":"","institution":"National Institute of Technology Tiruchirappalli","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Muthuchidambaranathan","middleName":"","lastName":"P","suffix":""}],"badges":[],"createdAt":"2022-07-06 08:44:11","currentVersionCode":1,"declarations":"","doi":"10.21203/rs.3.rs-1830533/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-1830533/v1","draftVersion":[],"editorialEvents":[],"editorialNote":"","failedWorkflow":false,"files":[{"id":23908981,"identity":"13f03ef2-5a9b-4451-96f2-85d7b18154b2","added_by":"auto","created_at":"2022-07-15 15:47:48","extension":"pdf","order_by":1,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":1002967,"visible":true,"origin":"","legend":"","description":"","filename":"SIWFinallatexformat.pdf","url":"https://assets-eu.researchsquare.com/files/rs-1830533/v1_covered.pdf"}],"financialInterests":"No competing interests reported.","formattedTitle":"Design and Analysis of CompactSubstrate-Integrated Waveguide (SIW)Cavity Resonator Based MicrofluidicBiosensor for X-Band Applications","fulltext":[{"header":"Full Text","content":"This preprint is available for \u003ca href='/article/rs-1830533/latest.pdf' target='_blank'\u003edownload as a PDF\u003c/a\u003e."}],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":false,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":true,"highlight":"","institution":"","isAcceptedByJournal":false,"isAuthorSuppliedPdf":true,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":false,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"Biosensors, microwell, substrate integrated waveguide (SIW), Polydimethylsiloxane (PDMS)","lastPublishedDoi":"10.21203/rs.3.rs-1830533/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-1830533/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"Biosensors are compact miniaturized devices to measure the biologicalsamples based on the molecular structure and convert the sameto electronic signals. The substrate Integrated Waveguide (SIW) cavitybased resonators loaded with a circular cavity can be used as a biosensorin a non invasive manner to detect the biological tissues in the sample with better efficiency and miniaturized structure.The biosensingsamples may vary from proteins to enzymes which has gained ahuge response in the industries likes medical, agriculture, food processingindustry and many more over the decades. The substrate materialof antenna is designed with Rogers RT/Duroid 5870 which has thedielectric constant of 2.33. The Rectangular patch antenna is thenloaded with the SIW vias for an enhanced performance of S parameterfrom -17.21 dB to -44.88dB operating at the X band (8 to 12GHz) frequencies. The microwell made from the Polydimethylsiloxane(PDMS) material is inserted into the patch infrom of circularslot to achieve the biosensing application. 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