Comment on “Risk of systemic lupus erythematosus in patients with endometriosis: a nationwide population‑based cohort study”

Maria I Zervou, Michail Matalliotakis, George N. Goulielmos
Archives of gynecology and obstetrics · 2021 · vol. 305(2) , pp. 543–544 · doi:10.1007/s00404-021-06037-3 · PMID:33755807 · W3137182966
letter OA: closed CC0 ⤵ 3 in-corpus citations
Full text JSON View on OpenAlex View on PubMed View at publisher
⚙ AI-generated summary by claude@2026-06+body, 2026-06-12 ⓘ

This commentary discusses the risk of systemic lupus erythematosus in patients with endometriosis, referencing prior research on their association and related immunobiology.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

⚙ AI-generated deep summary by claude@2026-06, 2026-06-12 · read from full text ⓘ

This paper is a brief commentary on a previously published nationwide population-based cohort study that examined the risk of developing systemic lupus erythematosus in patients with endometriosis. The comment addresses the findings in the context of endometriosis–autoimmunity research and highlights relevant background from earlier studies comparing clinical manifestations and serological autoimmune phenomena. A key limitation noted in such commentary formats is that it does not provide new primary data beyond interpretation of the original cohort study’s design and results. This paper is centrally about endometriosis — it is a comment specifically on “Risk of systemic lupus erythematosus in patients with endometriosis,” discussing how the cohort evidence fits into broader endometriosis–immune connections.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Full text 2,590 characters · extracted from oa-doi-fallback · click to expand
References Lin YH, Yang YC, Chen SF, Hsu CY, Shen YC (2020) Risk of systemic lupus erythematosus in patients with endometriosis: a nationwide population-based cohort study. Arch Gynecol Obstet 302:1197–1203 Pasoto SG, Abrao MS, Viana VST, Bueno C, Leon EP, Bonfa E (2005) Endometriosis and systemic lupus erythematosus: a comparative evaluation of clinical manifestations and serological autoimmune phenomena. Am J Reprod Immunol 53:85–93 Lebovic DI, Mueller MD, Taylor RN (2001) Immunobiology of endometriosis. Fertil Steril 75:1–10 Bianco B, Andre GM, Vilarino FL, Peluso C, Mafra FA, Christo-folini DM, Barbosa CP (2012) The possible role of genetic variants in autoimmune-related genes in the development of endometriosis. Hum Immunol 73(3):306–315 Matalliotaki C, Matalliotakis M, Zervou MI, Trivli A, Matalliotakis I, Mavromatidis G, Spandidos DA, Albertsen HM, Chettier R, Ward K, Goulielmos GN (2018) Co-existence of endometriosis with thirteen non gynecological co-morbidities: mutation analysis by whole exome sequencing. Mol Med Rep 18:5053–5057 Peluso C, Christofolini DM, Goldman CS, Mafra FA, Cavalcanti V, Barbosa CP, Bianco B (2013) TYK2 rs34536443 polymorphism is associated with a decreased susceptibility to endometriosis-related infertility. Hum Immunol 74:93–97 Deng X, Su Y, Wu H, Wu R, Zhang P, Dai Y, Chan T-M, Zhao M, Lu Q (2015) The role of microRNAs in autoimmune diseases with skin involvement. Scand J Immunol 81:153–165 Zubrzycka A, Zubrzycki M, Perdas E, Zubrzycka M (2020) Genetic, epigenetic, and steroidogenic modulation mechanisms in endometriosis. J Clin Med 9(5):1309. https://doi.org/10.3390/jcm9051309 Author information Authors and Affiliations Contributions MIZ: conceptualization, writing of the original draft, and data collection. MM: writing of the original draft and data collection. GNG: data collection, manuscript reviewing, and editing. Corresponding author Ethics declarations Conflict of interest The authors have declared no conflicts of interest. Additional information Publisher's Note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Rights and permissions About this article Cite this article Zervou, M.I., Matalliotakis, M. & Goulielmos, G.N. Comment on “Risk of systemic lupus erythematosus in patients with endometriosis: a nationwide population‑based cohort study”. Arch Gynecol Obstet 305, 543–544 (2022). https://doi.org/10.1007/s00404-021-06037-3 Received: Accepted: Published: Version of record: Issue date: DOI: https://doi.org/10.1007/s00404-021-06037-3

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

⚙ Ask this paper AI returns verbatim quotes from the full text · source: oa-doi-fallback ⓘ

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Condition tags

endometriosis

MeSH descriptors

Endometriosis Endometriosis Endometriosis Lupus Erythematosus, Systemic Lupus Erythematosus, Systemic Cohort Studies Female Humans Incidence Research

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

References (8)

Cited by (3)

Source provenance

europepmc
last seen: 2026-06-17T06:13:18.893374+00:00
openalex
last seen: 2026-06-10T17:14:06.276822+00:00
pubmed
last seen: 2026-05-13T22:24:49.034193+00:00
License: CC0 · commercial use OK