History of Adenomyosis
Adenomyosis was first described in 1860 by Carl Rokitansky, with von Recklinghausen coining the term adenomyoma uteri in 1882, and later distinguishing it from endometriosis.
One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works
This historical chapter traces how adenomyosis was first described and then conceptually separated from related entities like endometriosis. It recounts early 19th-century reports, including Rokitansky’s case (1860) with uterine mucosa nests, later recognition by Cullen of characteristic symptoms (lengthened menstrual periods and pain), and Sampson’s 1925 work distinguishing uterine “mucosal invasion” from extrauterine spread by introducing endometriosis; Frankl (1925) is credited with describing intramyometrial endometrial invagination as adenomyosis uteri. A key limitation noted is that some early “adenomyoma” descriptions would today be reclassified as endometriosis, complicating historical interpretation. Relevance to endometriosis: the chapter explicitly discusses Sampson’s separation of adenomyosis-like uterine invasion from peritoneal extrauterine endometriosis and cautions that early adenomyosis accounts may actually represent endometriosis, though its main focus is the history of adenomyosis.
Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works
Full text
5,753 characters
· extracted from
oa-doi-fallback
· 2 sections
· click to expand
Abstract
References
Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.
My notes (saved in your browser only)
Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works
Condition tags
Citation neighborhood
Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.
References (16)
- Adenomyosis uteri via openalex
- Discussion via openalex
- Inguinal endometriosis (often reported as endometrial tissue in the groin, adenomyoma in the groin, and adenomyoma of the round ligament via openalex
- Peritoneal endometriosis due to the menstrual dissemination of endometrial tissue into the peritoneal cavity via openalex
- The elusive adenomyosis of the uterus via openalex
- The elusive adenomyosis of the uterus—revisited via openalex
- W2025021247 via openalex
- W2035640485 via openalex
- W2110540431 via openalex
- W2141909819 via openalex
- W6750658089 via openalex
- W65513910 via openalex
- W168251674 via openalex
- W1545891414 via openalex
- W2010387940 via openalex
- W2019382328 via openalex
Source provenance
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- unpaywall
- last seen: 2026-09-15T06:33:26.365676+00:00